Erschienen in:
01.08.2017 | Gynecologic Cancers (NS Reed, Section Editor)
Early Cervical Cancer: Current Dilemmas of Staging and Surgery
verfasst von:
Tiffany Zigras, Genevieve Lennox, Karla Willows, Allan Covens
Erschienen in:
Current Oncology Reports
|
Ausgabe 8/2017
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Abstract
Purpose of Review
Advances in cervical cancer screening and treatment have resulted in high cure rates in developed countries for early-stage disease. Current research focuses on minimizing morbidity and maximizing quality of life.
Recent Findings
Imaging has been disappointing in identifying small volume metastases. Sentinel lymph node biopsy represents a significant advantage with high sensitivity, low false negative rates, reduced morbidity, and equivalent survival in recent studies compared to pelvic lymphadenectomy. Non-radical surgical options are currently being investigated for early cervical cancer in a number of large prospective studies in patients at low risk for metastases.
Summary
Evidence suggests that sentinel lymph node biopsy and non-radical surgery are safe approaches for the staging and management of early cervical cancer in appropriately selected patients with the potential to significantly reduce treatment-related morbidity.