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12.08.2021 | Original Article

Effect of behavioral counseling therapy with or without physical activity on inflammatory markers in adolescents with obesity: a randomized clinical trial

verfasst von: Adriana Carneiro Lambertucci, Mara Cristina Lofrano-Prado, Rafael Herling Lambertucci, João Paulo Botero, Ana Raimunda Dâmaso, Wagner Luiz do Prado

Erschienen in: Sport Sciences for Health | Ausgabe 2/2022

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Abstract

Background

The aim of the present study was to compare the effects 24 weeks of counseling-based therapy with or without recreational physical activity (RPA) on adipokines, biochemical parameters and anthropometric measurements in adolescents with obesity.

Methods

Seventy-four adolescents with obesity (40 girls) were randomly assigned into Counseling Group (CG) or Counseling + Recreational Physical Activity Group (C + RPAG). Both groups underwent behavioral counseling meetings weekly (1 h) for 12 weeks followed by monthly meetings for additional 12 weeks. C + RPAG adolescents performed RPA twice a week (1 h each) in the first 12 weeks. FGF21, PAI-1, leptin and adiponectin, glucose, insulin, blood lipids and anthropometric measurements were assessed at baseline and after 24 weeks.

Results

Time was important inducing reduction in BMI z-score (p = 0.03) and waist circumference (p = 0.01). The comparisons between groups showed no differences. Largest effect size was observed in C + RPAG for both measurements (BMI z-score, d = 0.60 and WC, d = 0.48). For biochemical parameters time was important with increase in glucose (p = 0.01, higher in CG, d = 0.57), cholesterol (p = 0.008, only in CG, d = 0.71), LDL-c (p = 0.05, higher in CG, d = 0.82), PAI-1 (p = 0.01, higher in C + RPAG, d = 0.54) and decrease in triacylglycerol (p = 0.05, higher in C + RPAG, d = 0.72).

Conclusion

Both therapies improved anthropometric parameters and, although there were no differences in the type of therapy applied in biochemical and adipokine parameters, better effects were observed in the group that had RPA.

Brazilian Registry of Clinical Trials (ReBEC) (July, 22 2020) identification number RBR-7tmpdb (http://www.ensaiosclinicos.gov.br/rg/RBR-7tmpdb/)

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Titel: Effect of behavioral counseling therapy with or without physical activity on inflammatory markers in adolescents with obesity: a randomized clinical trial
verfasst von: Adriana Carneiro Lambertucci
Mara Cristina Lofrano-Prado
Rafael Herling Lambertucci
João Paulo Botero
Ana Raimunda Dâmaso
Wagner Luiz do Prado
Publikationsdatum: 12.08.2021
Verlag: Springer Milan
Erschienen in: Sport Sciences for Health / Ausgabe 2/2022
Print ISSN: 1824-7490
Elektronische ISSN: 1825-1234
DOI: https://doi.org/10.1007/s11332-021-00819-7

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Effect of behavioral counseling therapy with or without physical activity on inflammatory markers in adolescents with obesity: a randomized clinical trial