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01.11.2012 | Original Paper

Effect of transcatheter aortic valve implantation on the ascending aorta’s elasticity

verfasst von: Manolis Vavuranakis, Dimitrios A. Vrachatis, Harisios Boudoulas, Theodore G. Papaioannou, Carmen Moldovan, Maria G. Kariori, Konstantinos I. Kalogeras, Panagiota G. Pietri, Constantinos Tentolouris, Christodoulos Stefanadis

Erschienen in: Clinical Research in Cardiology | Ausgabe 11/2012

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Abstract

Background

The elastic properties of the ascending aorta were studied before and 1 week after transcatheter aortic valve implantation (TAVI). Previous studies have shown that the distensibility of the ascending aorta was decreased in the early post-operative period after aortic valve replacement. Aortic stiffness is a major moderator of arterio-ventricular coupling and an independent predictor of cardiovascular risk and mortality. We evaluated the effect of TAVI on the elastic properties of the ascending aorta in the early post-operative period.

Methods

Aortic distensibility (AD) and Aortic Stiffness Index (ASI) were evaluated using echocardiographic techniques and brachial artery pressure obtained by sphygmomanometry 2–3 days before and 7–8 days after TAVI.

Results

A total of 30 patients (14 males) were studied with a mean age of 79.9 ± 4.7 years and aortic valve area before TAVI of 0.61 ± 0.16 cm². Mean arterial pressure decreased significantly after TAVI (from 89.6 ± 8.9 mmHg to 83.3 ± 10.9 mmHg, p = 0.004). AD did not change significantly after TAVI (pre: 1.89 ± 1.11 cm²/(dynes × 10⁶), post: 2.05 ± 1.50 cm²/(dynes × 10⁶); p = 0.813). ASI also remained unchanged (pre: 11.4 ± 6.5, post: 15.6 ± 14.9; p = 0.349).

Conclusions

The elastic properties of the ascending aorta did not change significantly in the early post-procedural period after TAVI. This may in part be attributable to the less invasive procedure (compared to aortic valve replacement) which has no effect on vasa vasorum flow.

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Titel: Effect of transcatheter aortic valve implantation on the ascending aorta’s elasticity
verfasst von: Manolis Vavuranakis
Dimitrios A. Vrachatis
Harisios Boudoulas
Theodore G. Papaioannou
Carmen Moldovan
Maria G. Kariori
Konstantinos I. Kalogeras
Panagiota G. Pietri
Constantinos Tentolouris
Christodoulos Stefanadis
Publikationsdatum: 01.11.2012
Verlag: Springer-Verlag
Erschienen in: Clinical Research in Cardiology / Ausgabe 11/2012
Print ISSN: 1861-0684
Elektronische ISSN: 1861-0692
DOI: https://doi.org/10.1007/s00392-012-0473-x

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Effect of transcatheter aortic valve implantation on the ascending aorta’s elasticity