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Erschienen in: Current Hepatology Reports 1/2024

18.01.2024

Endocrinology for the Hepatologist

verfasst von: Scott Isaacs, Arabella Isaacs

Erschienen in: Current Hepatology Reports | Ausgabe 1/2024

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Abstract

Purpose of review

The purpose of this review is to discuss endocrine diseases that affect the liver and how chronic liver disease affects endocrine function.

Recent findings

Over the past 2 decades, we have gained an expanding knowledge of the liver as an endocrine organ. There have been numerous discoveries in hepatic hormone and hepatokine synthesis, metabolism, and production of hormone binding proteins. Global awareness of metabolic dysfunction-associated steatotic liver disease (MASLD) is increasing as the most common cause of chronic liver disease, and its mutually detrimental relationship with type 2 diabetes (T2D), lipotoxicity, insulin resistance and the metabolic syndrome. Recent discoveries have elucidated mechanisms and a better understanding of cirrhosis-associated endocrinopathies.

Summary

The liver facilitates numerous endocrine functions and is a dynamic component of the endocrine system. This review will discuss endocrine disorders including diabetes, polycystic ovary syndrome (PCOS), thyroid disorders, adrenal insufficiency, growth hormone deficiency, osteosarcopenia, and male hypogonadism and the relationship to chronic liver disease.
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Metadaten
Titel
Endocrinology for the Hepatologist
verfasst von
Scott Isaacs
Arabella Isaacs
Publikationsdatum
18.01.2024
Verlag
Springer US
Erschienen in
Current Hepatology Reports / Ausgabe 1/2024
Elektronische ISSN: 2195-9595
DOI
https://doi.org/10.1007/s11901-024-00639-6

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