Introduction
Materials and methods
Protocol data extraction and outcomes evaluated
Electronic database search
Inclusion and exclusion criteria
Statistical analysis
Results
Retrieving researches
Patients features and surgery
References/year | Study design | Subjective assessment | Treatment features | Surgical approach | Follow-up | Post-operative outcomes |
---|---|---|---|---|---|---|
Abu-Samra et al. 2011 | Prospective controlled single-blinded study | VAS | Septal spur and/or chonca bullosa in 42 subjects | Standard and/or endoscopic septoplasty and/or turbinateplasty | 1–48 months | VAS ↓ improved in 81% of surgical patients (p = 0.001) |
Altin et al. 2019 | Retrospective non-randomized controlled study | VAS | Septal spur in 51/99 surgical subjects vs 48/99 medical ones | Endoscopic septoplasty | 1–6 months | VAS ↓ improved of 79.8% in surgical patients vs ↓ 7% in medical ones (p = 0.01) |
Behin et al. 2004 | Retrospective uncontrolled study | VAS | Septal spur and/or chonca bbullosa in 21/50 subjects | Standard and/or endoscopic septoplasty and/or turbinateplasty | 1–62 months | VAS ↓ improved in 95.8% of patients till no headache in 42.9% (p < 0.001) |
Bektas et al. 2011 | Retrospective uncontrolled study | VAS | Septal spur and/or chonca bullosa in 36 subjects | Endoscopic septoplasty | 1–6 months | VAS ↓ improved in 100% of patients till no headache in 52.7% (p < 0.001) |
Bilal et al. 2013 | Prospective uncontrolled study | VAS | Septal spur and/or chonca bullosa in 65 subjects | Standard and/or endoscopic septoplasty and/or turbinateplasty | 1–12 months | VAS ↓ improved in 52% of patients till no headache in 12.3% (p < 0.001) |
Cantone et al. 2014 | Retrospective randomized controlled study | VAS/ MIDAS/ Lund-Mackay | Chonca bullosa 53/102 in subjects vs 49/102 medical ones | Endoscopic chonca plasty | 1–6 months | VAS ↓ improved in 81% of patients while MIDAS ↓ 100% GRADE 3–4 switched to lower classes till no headache in 44% (p < 0.05) |
Guyuron et al. 2011 | Retrospective randomized controlled study | VAS/MIDAS/ MOS SF-36/ MSQoL | Septal spur and/or chonca bullosa in 79 subjects | Standard and/or endoscopic septoplasty and/or turbinateplasty | 1–60 months | All Scores ↓ improved in 90% of patients till no headache in 28% (p < 0.001 in all cases) |
Huang et al. 2008 | Retrospective uncontrolled study | VAS | Septal spur and/or chonca bullosa in 66 subjects | Standard and/or endoscopic septoplasty and/or turbinateplasty | 1–127 months | VAS ↓ improved in 81.8% of patients (p < 0.001) |
Hye Wee et al. 2015 | Prospective uncontrolled study | VAS/Lund-Mackay | Septal spur and/or chonca bullosa in 41/356 subjects | Standard and/or endoscopic septoplasty and/or turbinateplasty | 1–16 months | VAS ↓ improved in 80% of patients till no headache in 58.5% (p < 0.05) |
Kunachak et al. 2002 | Prospective uncontrolled study | VAS | Septal spur and/or chonca bullosa in 55 subjects | Endoscopic middle turbinate lateralization | 1–84 months | VAS ↓ improved in all cases 100% till no headache in 87% (p < 0.001) |
La Mantia et al. 2017 | Retrospective randomized controlled study | VAS/MIDAS | Septal spur and/or chonca bullosa in 47/94 surgical subjects vs 47/94 medical ones | Standard and/or endoscopic septoplasty and/or turbinateplasty | 1–6 months | VAS ↓ and MIDAS ↓ improved in 68% of surgical patients vs in 36% of medical ones (p < 0.001 in both scores) |
Madani et al. 2013 | Prospective uncontrolled study | VAS | Septal spur and/or chonca bullosa in 30 in subjects | Endoscopic septoplasty | 1–6 months | VAS ↓ improved of 72% in surgical patiens (p = 0.013) |
Mariotti et al. 2009 | Prospective uncontrolled study | VAS/ Lund-Mackay | Septal spur and/or chonca bullosa in 33 subjects | Standard and/or endoscopic septoplasty and/or turbinateplasty | 1–24 months | VAS ↓ improved in 84.8% of patients (p < 0.01) |
Mohebbi et al. 2009 | Prospective non-randomized study | VAS | Septal spur and/or chonca bullosa in 36 subjects | Standard and/or endoscopic septoplasty and/or turbinateplasty | 1–48 months | VAS ↓ improved in 83% of patients till no headache in 11% (p = 0.05) |
Peric et al. 2016 | Retrospective uncontrolled study | VAS | Septal spur and/or chonca bullosa in 42 subjects | Standard and/or endoscopic septoplasty and/or turbinateplasty | 1–24 months | VAS ↓ improved in 88.1% of patients |
Welge-Luessen et al. 2003 | Prospective uncontrolled study | VAS | Septal spur and/or chonca bullosa in 20 subjects | Standard and/or endoscopic septoplasty and/or turbinateplasty | 1–120 months | VAS ↓ improved in 75% of patients till no headache in 30% (p = 0.018) |
Yarmohammadi et al. 2014 | Prospective randomized controlled study | VAS | Septal spur and/or chonca bullosa in 22/44 surgical subjects and 22/44 medical ones | Standard and/or endoscopic septoplasty and/or turbinateplasty | 1–6 months | VAS ↓ better improvements in surgical group than medical (scores 0 vs 5.5 respectively; p < 0.001) |
Yazici et al. 2010 | Retrospective randomized controlled study | VAS | Septal spur and/or chonca bullosa in 38/53 surgical subjects vs 15/53 medical ones | Standard and/or endoscopic septoplasty and/or turbinateplasty | 1–6 months | VAS ↓ improved of 61% in surgical patients vs 4.5% in medical ones |
VAS outcomes comparison in surgical patients
Short–medium vs long-term outcomes
Surgical vs medical treatment
MIDAS outcomes
References | Patients | Pre-operative MIDAS | Postoperative MIDAS | ||||
---|---|---|---|---|---|---|---|
Grade 3–4 | Grade 1–2 | Grade 3–4 | Grade 1–2 | Grade 0 | p value | ||
Cantone et al. 2014 | 53 | 38 (72%) | 15 (28%) | 0 | 30 (56%) | 23 (44%) | < 0.00001 |
La Mantia et al. 2017 | 47 | 36 (76.60%) | 11 (23.4%) | 4 (8.5%) | 43 (91.5%) | – | < 0.00001 |
Segana et al. 2016 | 20 | 14 (70%) | 6 (30%) | 2 (10%) | 18 (15%) | – | = 0.0001 |
Total | 120 | 88 (73%) | 32 (27%) | 6 (5%) | 91 (76%) | – | < 0.00001 |