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Journal of Cardiovascular Translational Research
Erschienen in: Journal of Cardiovascular Translational Research 2/2013

01.04.2013

Endothelial Dysfunction and Cardiac Allograft Vasculopathy

verfasst von: Monica Colvin-Adams, Nonyelum Harcourt, Daniel Duprez

Erschienen in: Journal of Cardiovascular Translational Research | Ausgabe 2/2013

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Abstract

Cardiac allograft vasculopathy remains a major challenge to long-term survival after heart transplantation. Endothelial injury and dysfunction, as a result of multifactorial immunologic and nonimmunologic insults in the donor and the recipient, are prevalent early after transplant and may be precursors to overt cardiac allograft vasculopathy. Current strategies for managing cardiac allograft vasculopathy, however, rely on the identification and treatment of established disease. Improved understanding of mechanisms leading to endothelial dysfunction in heart transplant recipients may provide the foundation for the development of sensitive screening techniques and preventive therapies.
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Metadaten
Titel
Endothelial Dysfunction and Cardiac Allograft Vasculopathy
verfasst von
Monica Colvin-Adams
Nonyelum Harcourt
Daniel Duprez
Publikationsdatum
01.04.2013
Verlag
Springer US
Erschienen in
Journal of Cardiovascular Translational Research / Ausgabe 2/2013
Print ISSN: 1937-5387
Elektronische ISSN: 1937-5395
DOI
https://doi.org/10.1007/s12265-012-9414-3

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