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European Journal of Drug Metabolism and Pharmacokinetics

Ausgabe 1/2014

Inhalt (9 Artikel)

Original Paper

Darexaban (YM150), an oral direct factor Xa inhibitor, has no effect on the pharmacokinetics of digoxin

Takeshi Kadokura, Dorien Groenendaal, Marten Heeringa, Roelof Mol, Frank Verheggen, Alberto Garcia-Hernandez, Hartmut Onkels

Original Paper

Pharmacokinetic interaction of enrofloxacin/trimethoprim combination following single-dose intraperitoneal and oral administration in rats

Myung-Jin Choi, Sileshi Belew Yohannes, Seung-Jin Lee, Dereje Damte, Jong-Choon Kim, Joo-Won Suh, Seung-Chun Park

Original Paper

Effect of natural borneol on the pharmacokinetics and distribution of nimodipine in mice

Chun Wu, Qiongfeng Liao, Meicun Yao, Xinjun Xu, Yuting Zhou, Xueying Hou, Zhiyong Xie

Original Paper

Integration of preclinical and clinical knowledge to predict intravenous PK in human: Bilastine case study

Valvanera Vozmediano, Ignacio Ortega, John C. Lukas, Ana Gonzalo, Monica Rodriguez, Maria Luisa Lucero

Original Paper

The effect of mirabegron, a potent and selective β3-adrenoceptor agonist, on the pharmacokinetics of CYP2D6 substrates desipramine and metoprolol

Walter Krauwinkel, James Dickinson, Marloes Schaddelee, John Meijer, Reiner Tretter, Jeroen van de Wetering, Gregory Strabach, Marcel van Gelderen

Original Paper

Effect of chronic hypoxic hypoxia on oxidation and glucuronidation of carvedilol in rats

Shizuka Yamaura, Miki Fukao, Kazuya Ishida, Masato Taguchi, Yukiya Hashimoto

Original Paper

A clinical pharmacokinetic study comparing two azelastine hydrochloride nasal formulations in a single-dose design

Daniel Du, Darren Targett, Erhard Stolberg, Alessandra Canali