Ausgabe 3/2017
Inhalt (17 Artikel)
Enhancement of Curcumin Bioavailability Via the Prodrug Approach: Challenges and Prospects
Pahweenvaj Ratnatilaka Na Bhuket, Asma El-Magboub, Ian S. Haworth, Pornchai Rojsitthisak
Pharmacokinetics and Pharmacodynamics of Promising Arginase Inhibitors
Khaled S. Abdelkawy, Kelsey Lack, Fawzy Elbarbry
Pharmacokinetics of Roflumilast and Its Active Metabolite Roflumilast N-Oxide in Healthy Chinese Subjects After Single and Multiple Oral Doses
Qian Li, Yiya Wang, Lingye Liu, Pengcheng Ma, Li Ding
Optimizing the Clinical Use of Carvedilol in Liver Cirrhosis Using a Physiologically Based Pharmacokinetic Modeling Approach
Muhammad Fawad Rasool, Feras Khalil, Stephanie Läer
Effects of Grapefruit and Pomegranate Juices on the Pharmacokinetic Properties of Dapoxetine and Midazolam in Healthy Subjects
Khaled S. Abdlekawy, Ahmed M. Donia, Fawzy Elbarbry
Pharmacokinetics After Single Ascending Dose, Food Effect, and Safety of Sacubitril/Valsartan (LCZ696), an Angiotensin Receptor and Neprilysin Inhibitor, in Healthy Japanese Subjects
Mizuki Akahori, Surya Ayalasomayajula, Thomas Langenickel, Parasar Pal, Wei Zhou, Gangadhar Sunkara
Pharmacokinetic Interactions Between Mirabegron and Metformin, Warfarin, Digoxin or Combined Oral Contraceptives
Monique Groen-Wijnberg, Jan van Dijk, Walter Krauwinkel, Virginie Kerbusch, John Meijer, Reiner Tretter, Wenhui Zhang, Marcel van Gelderen
Supramolecular Complex of Ibuprofen with Larch Polysaccharide Arabinogalactan: Studies on Bioavailability and Pharmacokinetics
Mikhail V. Khvostov, Sergey A. Borisov, Tatjana G. Tolstikova, Alexander V. Dushkin, Biligma D. Tsyrenova, Yulia S. Chistyachenko, Nikolay E. Polyakov, Galina G. Dultseva, Andrey A. Onischuk, Sergey V. An’kov
The Effects of Rheum palmatum L. on the Pharmacokinetic of Major Diterpene Alkaloids of Aconitum carmichaelii Debx. in Rats
Yan Li, Yun-xia Li, Meng-jie Zhao, An Yuan, Xiao-hong Gong, Meng-jun Zhao, Cheng Peng
Oral Bioavailability and Mass Balance Studies of a Novel Anti-arrhythmic Agent Sulcardine Sulfate in Sprague–Dawley Rats and Beagle Dogs
You-li Lu, Shui-jun Li, Gang-yi Liu, Xiao-chuan Li, Ding Yang, Jing-ying Jia, Meng-qi Zhang, Hong-chao Zheng, Chen Yu, Fu Zhu, Yi-ping Wang
Influence of Renal Impairment on the Pharmacokinetics of Afatinib: An Open-Label, Single-Dose Study
Sabrina Wiebe, David Schnell, Raimund Külzer, Dietmar Gansser, Anne Weber, Gudrun Wallenstein, Atef Halabi, Anja Conrad, Sven Wind
Exploring the Feasibility of Biowaiver Extension of BCS Class III Drugs with Site-Specific Absorption Using Gastrointestinal Simulation Technology
Le Sun, Jin Sun, Zhonggui He
Influence of the Time of Intravenous Administration of Paracetamol on its Pharmacokinetics and Ocular Disposition in Rabbits
Agnieszka Karbownik, Agnieszka Bienert, Włodzimierz Płotek, Tomasz Grabowski, Magdalena Cerbin-Koczorowska, Anna Wolc, Edmund Grześkowiak
An Algorithm and R Program for Fitting and Simulation of Pharmacokinetic and Pharmacodynamic Data
Jijie Li, Kewei Yan, Lisha Hou, Xudong Du, Ping Zhu, Li Zheng, Cairong Zhu
Effects of High-cholesterol Diet on Pravastatin Disposition in the Perfused Rat Liver
Atsushi Kawase, Ayumi Handa, Masahiro Iwaki
Pharmacokinetic Effects of Cinnamic Acid, Amygdalin, Glycyrrhizic Acid and Liquiritin on Ephedra Alkaloids in Rats
Yinghong Tang, Mengkai Zheng, Yu-Lin Chen, Jianzhen Chen, Yu He
Strategies for Determining Correct Cytochrome P450 Contributions in Hepatic Clearance Predictions: In Vitro–In Vivo Extrapolation as Modelling Approach and Tramadol as Proof-of Concept Compound
Huybrecht T’jollyn, Jan Snoeys, Jan Van Bocxlaer, Lies De Bock, Pieter Annaert, Achiel Van Peer, Karel Allegaert, Geert Mannens, An Vermeulen, Koen Boussery