Ausgabe 4/2020
Inhalt (12 Artikel)
Protein Binding and Stability of Drug Candidates: The Achilles’ Heel in In Vitro Potency Assays
Ranjeet P. Dash, Jennifer A. Thomas, Clint Rosenfeld, Nuggehally R. Srinivas
Results from Drug–Drug Interaction Studies In Vitro and In Vivo Investigating the Effect of Finerenone on the Pharmacokinetics of Comedications
Roland Heinig, Michael Gerisch, Michaela Bairlein, Johannes Nagelschmitz, Stephanie Loewen
Pharmacokinetics of Polyethylene Glycol-Modified Canine Uricase Following Single and Multiple Intravenous Injections in Cynomolgus Monkeys
Haigang Li, JingJing Huo, Dan Sun, Liang Jiang, Chunlan Hu, Yanmin Bai, Xuefeng Ma, Haijuan Zhang, Xiaowei Shi, Zhilong Zhao, Jinchuan Zhou, Yongxin Lu, Chun Zhang
Population Pharmacokinetic Analysis of Tacrolimus in Adult Chinese Patients with Myasthenia Gravis: A Prospective Study
Jue Liu, Yun-Peng Guo, Zheng Jiao, Chong-Bo Zhao, Hui Wu, Zi-Ran Li, Xiao-Jun Cai, Jian-Ying Xi
An Open-Label, Randomized, Single-Dose, Crossover, Comparative Pharmacokinetics Study of YLB113 and the Etanercept Reference Product in Healthy Adult Male Subjects
Mustafa Shennak, Rana Al-Jaouni, Santhosh Kshirasagar, Ravi Sekhar Kasibhatta, Neelima Godse, Ahmad Al-Ghazawi, Praveen Vittala, Dhananjay Bakhle
Study on the Pharmacokinetics of Diazepam and Its Metabolites in Blood of Chinese People
Le-le Wang, Xin-xin Ren, Yi He, Guan-feng Cui, Zhi-wen Wei, Juan Jia, Jie Cao, Yao Liu, Bin Cong, Yong Niu, Ke-ming Yun
Development of a Physiologically-Based Pharmacokinetic Model of Δ9-Tetrahydrocannabinol in Mice, Rats, and Pigs
Janthima Methaneethorn, Kanyamas Naosang, Parichart Kaewworasut, Chomkanang Poomsaidorn, Manupat Lohitnavy
A Δ9-Tetrahydrocannabinol Physiologically-Based Pharmacokinetic Model Development in Humans
Janthima Methaneethorn, Chomkanang Poomsaidorn, Kanyamas Naosang, Parichart Kaewworasut, Manupat Lohitnavy
Mass Balance, Metabolism, and Excretion of Cenobamate, a New Antiepileptic Drug, After a Single Oral Administration in Healthy Male Subjects
Laurent Vernillet, Stephen A. Greene, Hong Wook Kim, Susan M. Melnick, Kelli Glenn
UFLC–MS/MS Determination and Population Pharmacokinetic Study of Tanshinol, Ginsenoside Rb1 and Rg1 in Rat Plasma After Oral Administration of Compound Danshen Dripping Pills
Tianqian Jin, Zuhui Liu, Yang Chu, Xiaohui Ma, Shuming Li, Xiangyang Wang, Genbei Wang, Shuiping Zhou, He Sun, Jin Yang
A Population Pharmacokinetics Model for Vancomycin Dosage Optimization Based on Serum Cystatin C
Jie-Jiu Lu, Ming Chen, Chun-Le Lv, Ren Zhang, Hua Lu, Dao-Hai Cheng, Shuang-Yi Tang, Tao-Tao Liu
Elution Profiles of Synthetic CaSO4 Hemihydrate Beads Loaded with Vancomycin and Tobramycin
Gerhard E. Maale, John J. Eager, Daniel K. Mohammadi, Flavio A. Calderon II