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Digestive Diseases and Sciences
Erschienen in: Digestive Diseases and Sciences 12/2014

01.12.2014 | Original Article

Evaluation of Cardiac Function by Two-Dimensional Speckle Tracking Echocardiography in Ulcerative Colitis Patients

verfasst von: Altug Cincin, Murat Sunbul, Tarık Kivrak, Halil Atas, Ibrahim Sari, Kursat Tigen, Tarik Kani, Hakan Akin, Nese Imeryuz, Yelda Basaran

Erschienen in: Digestive Diseases and Sciences | Ausgabe 12/2014

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Abstract

Purpose

Although ulcerative colitis (UC) shows obvious similarities with other autoimmune diseases, cardiac consequences have not adequately introduced. The aim of our study was to evaluate left ventricular (LV) function in UC patients by using novel echocardiographic parameters.

Results

Forty-five UC patients (mean age 37, 18 female) and 90 age- and sex-matched healthy volunteers (mean age 40, 38 female) included in the study. The mean disease activity score according to partial Mayo score was 2.16 ± 2.13. Mean global longitudinal strain (GLS) and global longitudinal strain rate (GLSR) measurements were significantly lower (−21.16 ± 2.71 vs. −23.36 ± 3.34; p < 0.001 and −1.33 ± 0.24 vs. −1.43 ± 0.24; p = 0.037, respectively), whereas global circumferential (−22.67 ± 3.66 vs. −23.37 ± 3.99; p = 0.140) and global radial strain (43.07 ± 8.58 vs. 44.12 ± 9.32; p = 0.545) measurements of the LV were similar in patients with UC compared with controls. The correlation coefficient (r) between GLS and partial Mayo score was −0.578 (p < 0.001).

Conclusion

Our study suggests that systolic cardiac deformation values are impaired in UC patients. Reduced GLS and GLSR might be an early indicator of cardiac involvement in this population.
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Metadaten
Titel
Evaluation of Cardiac Function by Two-Dimensional Speckle Tracking Echocardiography in Ulcerative Colitis Patients
verfasst von
Altug Cincin
Murat Sunbul
Tarık Kivrak
Halil Atas
Ibrahim Sari
Kursat Tigen
Tarik Kani
Hakan Akin
Nese Imeryuz
Yelda Basaran
Publikationsdatum
01.12.2014
Verlag
Springer US
Erschienen in
Digestive Diseases and Sciences / Ausgabe 12/2014
Print ISSN: 0163-2116
Elektronische ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-014-3274-4

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