nach oben

Head and Neck Pathology

Erschienen in:

01.06.2014 | Case Report

Extramedullary Plasmacytoma of the Trachea

verfasst von: Renu Sukumaran, Rekha A. Nair, Priya Mary Jacob, Sumod Mathew Koshy, Arun Peter Mathew

Erschienen in: Head and Neck Pathology | Ausgabe 2/2014

Einloggen, um Zugang zu erhalten

Abstract

Extramedullary plasmacytomas are plasma cell tumors that occur outside the bone marrow. They constitute around 4 % of all plasma cell neoplasms. The most common site of extramedullary plasmacytoma is the upper aerodigestive tract—nasal cavity, paranasal sinuses and oronasopharynx. We are presenting a case of extramedullary plasmacytoma of the trachea. Trachea is an extremely rare site of plasmacytoma. When extraosseous plasmacytoma occur in uncommon sites, the distinction from B cell lymphomas showing extensive plasmacytic differentiation can be difficult and diagnostically challenging.

Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW, editors. WHO classification of tumors of haematopoetic and lymphoid tissues. IARC: Lyon, France; 2008.

Bachar G, Goldstein D, Brown D, Tsang R, Lockwood G, Perez-Ordonez B, Irish J. Solitary extramedullary plasmacytoma of the head and neck-long term outcome analysis of 68 cases. Head Neck. 2008;30:1012–9.PubMedCrossRef

Reyhan M, Rercan F, Ergin M, Sukan A, Aydin M, Yapar F. Sonographic diagnosis of a tracheal extramedullary plasmacytoma. J Ultrasound Med. 2005;24:1031–4.PubMed

Papadopoulou A, Froudarakis M, Abatzoglou I, Koukourakis MI. Tracheal cancer treated with a short course of external and endoluminal radio-chemotherapy combined with cetuximab—a case report. J Contemp Brachyther. 2010;2:160–2.CrossRef

Rai SP, Kumar R, Bharadwaj R, Panda BN. Solitary tracheal plasmacytoma. Indian J Chest Dis Allied Sci. 2003;45:269–72.PubMed

Lomeo PE, McDonald JE, Finneman J. Shoreline. Extramedullary plasmacytoma of nasal sinus cavities. Am J Otolaryngol. 2007;28:50–1.PubMedCrossRef

Seegmiller AC, Xu Y, McKenna RW, Karandikar NJ. Immunophenotypic differentiation between neoplastic plasma cells in mature B cell lymphoma vs plasma cell myeloma. Am J Clin Pathol. 2007;127:176–81.PubMedCrossRef

Ely SA, Knowles DM. Expression of CD56/neural cell adhesion molecule correlates with the presence of lytic bone lesions in multiple myeloma and distinguishes myeloma from monoclonal gammopathy of undetermined significance and lymphomas with plasmacytoid differentiation. Am J Pathol. 2002;160:1293–9.PubMedCentralPubMedCrossRef

Van Camp B, Durie BG, Spier C, De Waele M, Van Riet I, Vela E, et al. Plasma cells in multiple myeloma express a natural killer cell-associated antigen:cD56 (NKH_1;Leu-19). Blood. 1990;76:377–82.PubMed

10.

Kremer M, Ott G, Nathrath M, Specht K, Stecker K, Alexiou C, et al. Primary extramedullary plasmacytoma and multiple myeloma: phenotypic differences revealed by immunohistochemical analysis. J Pathol. 2005;205:92–101.PubMedCrossRef

11.

Hussong JW, Perkins SL, Schnitzer B, Hargreaves H, Frizzera G. Extramedullary plasmacytoma : a form of marginal zone lymphoma ? Am J Clin Pathol. 1999;111:111–6.PubMed

12.

Bink K, Haralambieva E, Kremer M, Ott G, Beham-Schmid C, de Leval L, et al. Primary extramedullary plasmacytoma: similarities with and differences from multiple myeloma revealed by interphase cytogenetics. Heamatologica. 2008;93:623–6.CrossRef

13.

Dimopoulos MA, Hamilos G. Solitary bone plasmacytoma and extramedullary plasmacytoma. Curr Treat Options Oncol. 2002;3:255–9.PubMedCrossRef

14.

Alexiou C, Kau RJ, Dietzfelbinger H, Kremer M, Spiess JC, Schratzenstaller B, et al. Extramedullary plasmacytoma: tumor occurrence and therapeutic concepts. Cancer. 1999;85:2305–14.PubMedCrossRef

Titel: Extramedullary Plasmacytoma of the Trachea
verfasst von: Renu Sukumaran
Rekha A. Nair
Priya Mary Jacob
Sumod Mathew Koshy
Arun Peter Mathew
Publikationsdatum: 01.06.2014
Verlag: Springer US
Erschienen in: Head and Neck Pathology / Ausgabe 2/2014
Elektronische ISSN: 1936-0568
DOI: https://doi.org/10.1007/s12105-013-0491-7

Springer Medizin

Extramedullary Plasmacytoma of the Trachea

Abstract

Neu im Fachgebiet Pathologie

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren

Personalisierte Medizin in der Onkologie

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 2/2014

Transcriptionally-Active Human Papillomavirus is Consistently Retained in the Distant Metastases of Primary Oropharyngeal Carcinomas

Cherubism

Cheilitis Granulomatosa: A Review

Mammary Analogue Secretory Carcinoma of the Parotid Gland as a Secondary Malignancy in a Childhood Survivor of Atypical Teratoid Rhabdoid Tumor

Schwannoma-Like Pleomorphic Adenoma: A Case Report with Review of the Literature

Painful Unilateral Temporalis Muscle Enlargement: Reactive Masticatory Muscle Hypertrophy

Neu im Fachgebiet Pathologie

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren

Personalisierte Medizin in der Onkologie