Familial Cancer

BRCA1 Norway: comparison of classification for BRCA1 germline variants detected in families with suspected hereditary breast and ovarian cancer between different laboratories

• Open Access
• Original Article

Henrikke N. Hovland, Rafal Al-Adhami, Sarah Louise Ariansen, Marijke Van Ghelue, Wenche Sjursen, Sigrid Lima, Marte Bolstad, Amund H. Berger, Hildegunn Høberg-Vetti, Per Knappskog, Bjørn Ivar Haukanes, Ingvild Aukrust, Elisabet Ognedal

Rare germline variants in the AXIN2 gene in families with colonic polyposis and colorectal cancer

• Original Article

James M. Chan, Mark Clendenning, Sharelle Joseland, Peter Georgeson, Khalid Mahmood, Romy Walker, Julia Como, Jihoon E. Joo, Susan Preston, Ryan A. Hutchinson, Bernard J. Pope, Andrew Metz, Catherine Beard, Rebecca Purvis, Julie Arnold, Varnika Vijay, Galina Konycheva, Nathan Atkinson, Susan Parry, Mark A. Jenkins, Finlay A. Macrae, Christophe Rosty, Ingrid M. Winship, Daniel D. Buchanan

Monoallelic MUTYH pathogenic variants ascertained via multi-gene hereditary cancer panels are not associated with colorectal, endometrial, or breast cancer

• Original Article

Amanda Bartenbaker Thompson, Erin G. Sutcliffe, Kevin Arvai, Maegan E. Roberts, Lisa R. Susswein, Megan L. Marshall, Rebecca Torene, Kristen J. Vogel Postula, Kathleen S. Hruska, Shaochun Bai

Detecting inversions in routine molecular diagnosis in MMR genes

• Original Article

Edwige Kasper, Sophie Coutant, Sandrine Manase, Stéphanie Vasseur, Pierre Macquère, Gaëlle Bougeard, Laurence Faivre, Olivier Ingster, Stéphanie Baert-Desurmont, Claude Houdayer

Colectomy and desmoid tumours in familial adenomatous polyposis: a systematic review and meta-analysis

• Open Access
• Review

Arthur S. Aelvoet, Daphne Struik, Barbara A. J. Bastiaansen, Willem A. Bemelman, Roel Hompes, Patrick M. M. Bossuyt, Evelien Dekker

Juvenile polyposis diagnosed with an integrated histological, immunohistochemical and molecular approach identifying new SMAD4 pathogenic variants

• Open Access
• Original Article

Andrea Mafficini, Lodewijk A. A. Brosens, Maria L. Piredda, Cristian Conti, Paola Mattiolo, Giulia Turri, Maria G. Mastrosimini, Sara Cingarlini, Stefano F. Crinò, Matteo Fassan, Paola Piccoli, Michele Simbolo, Alessia Nottegar, Rita T. Lawlor, Alfredo Guglielmi, Aldo Scarpa, Corrado Pedrazzani, Claudio Luchini

Intestinal and extraintestinal neoplasms in patients with NTHL1 tumor syndrome: a systematic review

• Review

S. H. Beck, A. M. Jelsig, H. M. Yassin, L. J. Lindberg, K. A. W. Wadt, J. G. Karstensen

Long-term chemoprevention in patients with adenomatous polyposis coli: an observational study

• Original Article

Teresa M. Neuhann, Katharina Haub, Verena Steinke-Lange, Monika Morak, Andreas Laner, Melanie Locher, Elke Holinski-Feder

Medullary thyroid cancer and pheochromocytoma in MEN2A: are there parent of origin effects on disease expression?

• Short Communication

Andreas Machens, Kerstin Lorenz, Frank Weber, Henning Dralle

Physicians’ experience, practice and education, on genetic testing and genetic counseling: a nationwide survey study in Greece

• Original Article

Elena Fountzilas, Paraskevi Apostolou, Angelo V. Vasiliadis, Dimitra Aivazi, Emmanouil Saloustros, Florentia Fostira

Collaborative Group of the Americas on Inherited Gastrointestinal Cancers (CGA-IGC) Annual Virtual Meeting, November 13–15, 2021

• Abstract

InSiGHT 2022 Abstract Publishing and Best Abstract Awards

• Abstracts