Skip to main content
Erschienen in: Journal of Behavioral Medicine 5/2019

22.01.2019

Familial support following childhood sexual abuse is associated with longer telomere length in adult females

verfasst von: David W. Sosnowski, Wendy Kliewer, Timothy P. York, Ananda B. Amstadter, Colleen K. Jackson-Cook, Marcia A. Winter

Erschienen in: Journal of Behavioral Medicine | Ausgabe 5/2019

Einloggen, um Zugang zu erhalten

Abstract

Robust associations between adverse childhood experiences and shortened telomere length exist, but few studies have examined factors that may moderate this association, particularly with a resilience framework. The present study examined the association between exposure to childhood sexual abuse (and abuse severity) and mean telomere length, and whether social support and optimism moderated this association. The sample included 99 White monozygotic female twins, ranging in age from 35 to 70 (Mage = 52.74, SD = 8.55 years), who provided a blood sample for telomere assay, and data on their childhood sexual abuse history, trait optimism, and current social support. Linear mixed effects models were employed to test study hypotheses. There were no effects of exposure to abuse or abuse severity on mean telomere length, nor were there main or moderating effects of optimism, in analyses of the full sample. However, in analyses that only included women exposed to abuse, there was an abuse type × support interaction: among women who experienced abuse in forms other than intercourse, higher levels of social support were associated with longer mean telomere length. Findings from the current study clarify the role of childhood sexual abuse in telomere attrition, and identify one factor that may protect against the negative biological effects of childhood sexual abuse.
Literatur
Zurück zum Zitat Browne, A., Finkelhor, D., Baron, L., Briere, J., Ellison, J., Friedrich, W., et al. (1986). Impact of child sexual abuse: A review of the research. Psychological Bulletin, 99, 66–77.CrossRefPubMed Browne, A., Finkelhor, D., Baron, L., Briere, J., Ellison, J., Friedrich, W., et al. (1986). Impact of child sexual abuse: A review of the research. Psychological Bulletin, 99, 66–77.CrossRefPubMed
Zurück zum Zitat Cohen, S., & Wills, T. A. (1985). Stress, social support, and the buffering hypothesis. Psychological Bulletin, 98, 310–357.CrossRefPubMed Cohen, S., & Wills, T. A. (1985). Stress, social support, and the buffering hypothesis. Psychological Bulletin, 98, 310–357.CrossRefPubMed
Zurück zum Zitat Haycock, P. C., Heydon, E. E., Kaptoge, S., Butterworth, A. S., Thompson, A., & Willeit, P. (2014). Leucocyte telomere length and risk of cardiovascular disease: Systematic review and meta-analysis. British Medical Journal, 349, 1–11. https://doi.org/10.1136/bmj.g4227 CrossRef Haycock, P. C., Heydon, E. E., Kaptoge, S., Butterworth, A. S., Thompson, A., & Willeit, P. (2014). Leucocyte telomere length and risk of cardiovascular disease: Systematic review and meta-analysis. British Medical Journal, 349, 1–11. https://​doi.​org/​10.​1136/​bmj.​g4227 CrossRef
Zurück zum Zitat Kendler, K. S., & Prescott, C. A. (2006). Genes, environment, and psychopathology: Understanding the causes of psychiatric and substance use disorders. New York, NY: Guilford Press. Kendler, K. S., & Prescott, C. A. (2006). Genes, environment, and psychopathology: Understanding the causes of psychiatric and substance use disorders. New York, NY: Guilford Press.
Zurück zum Zitat Lazarus, R. S., & Folkman, S. (1984). Stress, appraisal, and coping. New York, NY: Springer. Lazarus, R. S., & Folkman, S. (1984). Stress, appraisal, and coping. New York, NY: Springer.
Zurück zum Zitat Scheier, M. F., & Carver, C. S. (1985). Optimism, coping, and health: Assessment and implications of generalized outcome expectancies. Health Psychology, 4, 219.CrossRefPubMed Scheier, M. F., & Carver, C. S. (1985). Optimism, coping, and health: Assessment and implications of generalized outcome expectancies. Health Psychology, 4, 219.CrossRefPubMed
Zurück zum Zitat Slagboom, P. E., Droog, S., & Boomsma, D. I. (1994). Genetic determination of telomere size in humans: A twin study of three age groups. American Journal of Human Genetics, 55, 876–882.PubMedPubMedCentral Slagboom, P. E., Droog, S., & Boomsma, D. I. (1994). Genetic determination of telomere size in humans: A twin study of three age groups. American Journal of Human Genetics, 55, 876–882.PubMedPubMedCentral
Zurück zum Zitat Spitzer, R. L., Williams, J. B., & Gibbon, M. (1987). Structured Clinical Interview for DSM-III-R. New York: New York State Psychiatric Institute Biometrics Research Department. Spitzer, R. L., Williams, J. B., & Gibbon, M. (1987). Structured Clinical Interview for DSM-III-R. New York: New York State Psychiatric Institute Biometrics Research Department.
Metadaten
Titel
Familial support following childhood sexual abuse is associated with longer telomere length in adult females
verfasst von
David W. Sosnowski
Wendy Kliewer
Timothy P. York
Ananda B. Amstadter
Colleen K. Jackson-Cook
Marcia A. Winter
Publikationsdatum
22.01.2019
Verlag
Springer US
Erschienen in
Journal of Behavioral Medicine / Ausgabe 5/2019
Print ISSN: 0160-7715
Elektronische ISSN: 1573-3521
DOI
https://doi.org/10.1007/s10865-019-00014-7

Weitere Artikel der Ausgabe 5/2019

Journal of Behavioral Medicine 5/2019 Zur Ausgabe

Demenzkranke durch Antipsychotika vielfach gefährdet

23.04.2024 Demenz Nachrichten

Wenn Demenzkranke aufgrund von Symptomen wie Agitation oder Aggressivität mit Antipsychotika behandelt werden, sind damit offenbar noch mehr Risiken verbunden als bislang angenommen.

Weniger postpartale Depressionen nach Esketamin-Einmalgabe

Bislang gibt es kein Medikament zur Prävention von Wochenbettdepressionen. Das Injektionsanästhetikum Esketamin könnte womöglich diese Lücke füllen.

„Psychotherapie ist auch bei sehr alten Menschen hochwirksam!“

22.04.2024 DGIM 2024 Kongressbericht

Die Kombination aus Medikamenten und Psychotherapie gilt als effektivster Ansatz bei Depressionen. Das ist bei betagten Menschen nicht anders, trotz Besonderheiten.

Auf diese Krankheiten bei Geflüchteten sollten Sie vorbereitet sein

22.04.2024 DGIM 2024 Nachrichten

Um Menschen nach der Flucht aus einem Krisengebiet bestmöglich medizinisch betreuen zu können, ist es gut zu wissen, welche Erkrankungen im jeweiligen Herkunftsland häufig sind. Dabei hilft eine Internetseite der CDC (Centers for Disease Control and Prevention).

Update Psychiatrie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.