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Acta Diabetologica

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01.02.2013 | Case Report

G6PD deficiency-induced hemolysis in a Chinese diabetic patient: a case report with clinical and molecular analysis

verfasst von: Xue-Jiang Gu, Shuo-Ping Chen, Sheng-Jie Ge, Le-Qun Zheng, Da-Wang Wang, Fei-Xia Shen

Erschienen in: Acta Diabetologica | Ausgabe 1/2013

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Abstract

A 59-year-old Chinese male patient was admitted at diagnosis of type1 diabetes with ketoacidosis. During the normalization of blood glucose with insulin, the patient developed acute hemolysis. The factors predisposing to hemolysis were not found, except the significantly diminished activity of glucose-6-phosphate dehydrogenase (G6PD). DNA analysis did not show any coding or intronic mutation in the G6PD gene. This is the first reported case of a Chinese patient in diabetic ketoacidosis with hemolysis induced by G6PD deficiency in the absence of mutations in the G6PD gene.

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Titel: G6PD deficiency-induced hemolysis in a Chinese diabetic patient: a case report with clinical and molecular analysis
verfasst von: Xue-Jiang Gu
Shuo-Ping Chen
Sheng-Jie Ge
Le-Qun Zheng
Da-Wang Wang
Fei-Xia Shen
Publikationsdatum: 01.02.2013
Verlag: Springer Milan
Erschienen in: Acta Diabetologica / Ausgabe 1/2013
Print ISSN: 0940-5429
Elektronische ISSN: 1432-5233
DOI: https://doi.org/10.1007/s00592-010-0236-y

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