Introduction
Material and methods
Subjects
Anthropometric measures
Dual-energy x-ray absorptiometry
Measurement of aerobic fitness
Blood pressure
Echocardiography
Blood samples
Statistical analyses
Results
Variable | Boys (n = 92) | Girls (n = 78) | P value |
---|---|---|---|
Baseline | |||
Age (year) | 10.0 ± 0.6 | 9.8 ± 0.6 | 0.03 |
Height (cm) | 141 ± 7 | 141 ± 7 | 0.69 |
Body mass (kg) | 35.2 ± 7.4 | 34.6 ± 6.6 | 0.57 |
BMI (kg/m2) | 17.5 ± 2.6 | 17.4 ± 2.7 | 0.90 |
Total body fat (kg) | 6.2 ± 4.6 | 8.0 ± 4.6 | 0.01 |
Percent body fat (%) | 16.1 ± 8.3 | 22.0 ± 8.5 | < 0.001 |
Abdominal fat (kg) | 2.3 ± 2.0 | 3.2 ± 2.2 | 0.01 |
Fat distribution (abdominal fat/total body fat) | 0.36 ± 0.04 | 0.37 ± 0.05 | 0.09 |
Fitness (ml/min/kg) | 42 ± 7 | 36 ± 6 | < 0.001 |
Maximum heart rate (beats/min) | 189 ± 14 | 184 ± 16 | 0.03 |
Respiratory exchange ratio | 1.0 ± 0.1 | 1.0 ± 0.1 | 0.64 |
Systolic blood pressure (mmHg) | 104 ± 8 | 104 ± 9 | 0.75 |
Diastolic blood pressure (mmHg) | 60 ± 5 | 60 ± 6 | 0.48 |
Pulse pressure (mmHg) | 44 ± 8 | 43 ± 7 | 0.29 |
Left ventricular mass (g/m) | 53.9 ± 12.0 | 48.3 ± 11.3 | 0.002 |
Left atrial diameter (mm/m) | 19.9 ± 2.4 | 19.5 ± 2.0 | 0.22 |
Galectin-3 (AU) | 4.34 ± 0.31 | 4.44 ± 0.55 | 0.12 |
Tanner stage score | 1.0 ± 0.0 | 1.0 ± 0.2 | 0.06 |
Follow-up | Boys (n = 84) | Girls (n = 68) | |
Age (year) | 11.9 ± 0.6 | 11.8 ± 0.6 | 0.16 |
Height (cm) | 152 ± 8 | 153 ± 8 | 0.31 |
Body mass (kg) | 43.2 ± 8.6 | 43.9 ± 9.1 | 0.62 |
BMI (kg/m2) | 18.5 ± 2.8 | 18.6 ± 3.2 | 0.97 |
Increase in total body fat (kg) | 2.1 ± 2.6 | 2.2 ± 2.4 | 0.95 |
Increase in abdominal fat (kg) | 1.0 ± 1.2 | 1.1 ± 1.5 | 0.48 |
Increase in percent body fat (%) | 1.4 ± 4.0 | 0.0 ± 3.8 | 0.03 |
Change in fat distribution | 0.02 ± 0.03 | 0.03 ± 0.15 | 0.32 |
Tanner stage score | 2.3 ± 0.9 | 2.7 ± 0.8 | 0.007 |
Variable | n = 170 |
---|---|
Baseline | |
Height | 0.11 (0.12) |
Body mass | *0.28 (< 0.001) |
BMI | *0.29 (< 0.001) |
Total body fat | *0.31 (< 0.001) |
Percent body fat | *0.30 (< 0.001) |
Abdominal fat | *0.30 (< 0.001) |
Body fat distribution | *0.20 (0.01) |
Fitness | − 0.11 (0.15) |
Systolic blood pressure | 0.03 (0.69) |
Diastolic blood pressure | *− 0.16 (0.03) |
Pulse pressure | *0.16 (0.04) |
Left ventricular mass | *0.31 (< 0.001) |
Left atrial diameter | *0.17 (0.03) |
Relative wall thickness | *0.18 (0.02) |
Follow-up | n = 152 |
Increase in TBF | *0.16 (0.04) |
Increase in AFM | 0.14 (0.09) |
Increase in percent body fat | 0.01 (0.88) |
Change in body fat distribution | − 0.01 (0.87) |