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Neurological Sciences

Erschienen in:

30.05.2019 | Quiz Cases

Ganglioneuroblastoma in children

verfasst von: Ioana Badiu Tișa, Gabriel Samașca, Cornel Aldea, Iulia Lupan, Dorin Farcau, Peter Makovicky

Erschienen in: Neurological Sciences | Ausgabe 9/2019

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Abstract

Introduction

Neuroblastoma ranks third among pediatric malignancies.

Case report

The case of a 3-year-old child is presented, who suddenly had frequent, unproductive, emetic cough; fever; and weight loss. Lung X-ray showed an opacity situated in the posterior superior mediastinum. Thoracic ultrasound revealed a slightly inhomogeneous, hypoechoic mass located in the posterior superior mediastinum. Computed tomography evidenced a tumor mass with homogeneous appearance in the costo-vertebral groove. Histological examination confirmed the diagnosis of ganglioneuroblastoma.

Conclusion

Although history and clinical examination provided few elements, diagnosis was made based on imaging and histopathological examination.

Ater JL (2015) Neuroblastoma. In: Nelson Textbook of Pediatrics 20^th. Elsevier, Philadelphia, pp 1709–1711

Cabana M, Lars M, Wagner MD (2018) Neuroblastoma. In: the 5-minute pediatric consult. 8-th edition. Wolters Kluwer Health, Philadelphia, pp 639–641

Henderson TO, Bhatia S, Pinto N et al (2011) Racial and ethnic disparities in risk and survival in children with neuroblastoma: a Children’s Oncology Group study. J Clin Oncol 29:76–82CrossRefPubMed

Shimada H, Ambros IM, Dehner LP, Hata JI, Joshi VV, Roald B, Stram DO, Gerbing RB, Lukens JN, Matthay KK, Castleberry RP (1999) The International Neuroblastoma Pathology Classification (the Shimada system). Cancer 86:364–372CrossRefPubMed

Morgenstern DA, London WB, Stephens D, Volchenboum SL, Hero B, di Cataldo A, Nakagawara A, Shimada H, Ambros PF, Matthay KK, Cohn SL, Pearson ADJ, Irwin MS (2014) Metastatic neuroblastoma confined to distant lymph nodes (stage 4N) predicts outcome in patients with stage 4 disease: a study from the International Neuroblastoma Risk Group Database. J Clin Oncol 32:1228–1235CrossRefPubMedPubMedCentral

Brisse HJ, McCarville MB, Granata C et al (2011) Guidelines for imaging and staging of neuroblastic tumors: consensus report from the International Neuroblastoma Risk Group Project. Radiology 261:243–257CrossRefPubMed

Hel W-G, Yan Y, Tang W et al (2017) Clinical and biological features of neuroblastic tumors: a comparison of neuroblastoma and ganglioneuroblastoma. Oncotarget 23:37730–33739

Vo KT, Matthay KK, Neuhaus J, London WB, Hero B, Ambros PF, Nakagawara A, Miniati D, Wheeler K, Pearson ADJ, Cohn SL, DuBois SG (2014) Clinical, biologic and prognostic differences on the basis of primary tumor site in neuroblastoma: a report from the international neuroblastoma risk group project. J Clin Oncol 32:3169–3176CrossRefPubMedPubMedCentral

Kaatsch P (2010) Epidemiology of childhood cancer. Cancer Treat Rev 36:277–285CrossRefPubMed

10.

Jamer T, Pytrus T, Zaleska-Dorobisz U et al (2018) Ganglioneuroblastoma in a child with chronic abdominal pain - a case report. Dev Period Med 22:364–370PubMed

11.

Manjaly JG, Alexander VR, Pepper CM et al (2015) Primary cervical ganglioneuroblastoma. Int J Pediatr Otorhinolaryngol 79:1007–1012CrossRefPubMed

12.

Steenberge SP, Prayson RA (2014) Pediatric cerebral ganglioneuroblastoma. J Clin Neurosci 21:2023–2025CrossRefPubMed

13.

Nabavizadeh SA, Feygin T, Harding BN, Bilaniuk LT, Zimmerman RA, Vossough A (2014) Imaging findings of patients with metastatic neuroblastoma to the brain. Acad Radiol 21:329–337CrossRefPubMed

14.

Fernandez-Pineda I, Sandoval JA, Davidoff AM (2015) Hepatic metastatic disease in pediatric and adolescent solid tumors. World J Hepatol 7:1807–1817CrossRefPubMedPubMedCentral

15.

Gauchan E, Sharma P, Ghartimagar D, Ghosh A (2017) Ganglioneuroblastoma in a newborn with multiple metastases: a case report. J Med Case Rep 11:239CrossRefPubMedPubMedCentral

16.

Federico SM, Brady SL, Pappo A, Wu J, Mao S, McPherson VJ, Young A, Furman WL, Kaufman R, Kaste S (2015) The role of chest computed tomography (CT) as a surveillance tool in children with high-risk neuroblastoma. Pediatr Blood Cancer 62:976–981CrossRefPubMedPubMedCentral

17.

Takeda Y, Sano H, Kawano A, Mochizuki K, Takahashi N, Kobayashi S, Ohara Y, Tasaki K, Hosoya M, Kikuta A (2018) Usefulness of fluorodeoxyglucose positron emission tomography / computed tomography for detection of a neuroblastic nodule in a ganglioneuroblastoma: a case report. J Med Case Rep 12:119CrossRefPubMedPubMedCentral

18.

Defferrari R, Mazzocco K, Ambros IM, Ambros PF, Bedwell C, Beiske K, Bénard J, Berbegall AP, Bown N, Combaret V, Couturier J, Erminio G, Gambini C, Garaventa A, Gross N, Haupt R, Kohler J, Jeison M, Lunec J, Marques B, Martinsson T, Noguera R, Parodi S, Schleiermacher G, Tweddle DA, Valent A, van Roy N, Vicha A, Villamon E, Tonini GP (2015) Influence of segmental chromosome abnormalities on survival in children over the age of 12 months with unresectable localised peripheral neuroblastic tumours without MYCN amplification. Br J Cancer 112:290–295CrossRefPubMed

19.

Schleiermacher G, Michon J, Ribeiro A, Pierron G, Mosseri V, Rubie H, Munzer C, Bénard J, Auger N, Combaret V, Janoueix-Lerosey I, Pearson A, Tweddle DA, Bown N, Gerrard M, Wheeler K, Noguera R, Villamon E, Cañete A, Castel V, Marques B, de Lacerda A, Tonini GP, Mazzocco K, Defferrari R, de Bernardi B, di Cataldo A, van Roy N, Brichard B, Ladenstein R, Ambros I, Ambros P, Beiske K, Delattre O, Couturier J (2011) Segmental chromosomal alterations lead to a higher risk of relapse in infants with MYCN-non-amplified localised unresectable/disseminated neuroblastoma. Br J Cancer 105:1940–1948CrossRefPubMedPubMedCentral

20.

Okamatsu C, London WB, Naranjo A, Hogarty MD, Gastier-Foster JM, Look AT, LaQuaglia M, Maris JM, Cohn SL, Matthay KK, Seeger RC, Saji T, Shimada H (2009) Clinicopathological characteristics of ganglioneuroma and ganglioneuroblastoma: a report from the CCG and COG. Pediatr Blood Cancer 53:563–569CrossRefPubMedPubMedCentral

21.

Strother DR, London WB, Schmidt ML, Brodeur GM, Shimada H, Thorner P, Collins MH, Tagge E, Adkins S, Reynolds CP, Murray K, Lavey RS, Matthay KK, Castleberry R, Maris JM, Cohn SL (2012) Outcome after surgery alone or with restricted use of chemotherapy for patients with low-risk neuroblastoma: results of Children’s Oncology Group study P9641. J Clin Oncol 30:1842–1848CrossRefPubMedPubMedCentral

22.

Nuchtern JG, London WB, Barnewolt CE, Naranjo A, McGrady PW, Geiger JD, Diller L, Schmidt ML, Maris JM, Cohn SL, Shamberger RC (2012) A prospective study of expectant observation as primary therapy for neuroblastoma in young infants: a Children’s Oncology Group study. Ann Surg 256:573–580CrossRefPubMedPubMedCentral

23.

Decarolis B, Simon T, Krug B, Leuschner I, Vokuhl C, Kaatsch P, von Schweinitz D, Klingebiel T, Mueller I, Schweigerer L, Berthold F, Hero B (2016) Treatment and outcome of Ganglioneuroma and Ganglioneuroblastoma intermixed. BMC Cancer 16:542CrossRefPubMedPubMedCentral

24.

Yang T, Huang Y, Xu T, Tan T, Yang J, Pan J, Hu C, Li J, Zou Y (2017) Surgical management and outcomes of ganglioneuroma and ganglioneuroblastoma-intermixed. Pediatr Surg Int 33:955–959CrossRefPubMed

Titel: Ganglioneuroblastoma in children
verfasst von: Ioana Badiu Tișa
Gabriel Samașca
Cornel Aldea
Iulia Lupan
Dorin Farcau
Peter Makovicky
Publikationsdatum: 30.05.2019
Verlag: Springer International Publishing
Erschienen in: Neurological Sciences / Ausgabe 9/2019
Print ISSN: 1590-1874
Elektronische ISSN: 1590-3478
DOI: https://doi.org/10.1007/s10072-019-03932-1

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