Erschienen in:
01.08.2008
Gastric Remnant Adenocarcinoma with Micropapillary Component
verfasst von:
Takeshi Kondo, Riko Kitazawa, Sohei Kitazawa
Erschienen in:
Digestive Diseases and Sciences
|
Ausgabe 8/2008
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Excerpt
An invasive micropapillary carcinoma (IMPC) is defined as a carcinoma composed of small clusters of tumor cells lying within clear spaces simulating vascular channels [
1]. It is a histological variant of invasive breast carcinoma with poor clinical prognosis [
2,
3]. This distinct histological pattern has been described in various organs, including the urinary bladder, lung, ovary, and major salivary glands [
4‐
8]. Although rarely observed as a pure histological component, IMPC is usually mixed with otherwise conventional carcinoma [
3] and is therefore often referred to as carcinoma with a micropapillary component. In cases of adenocarcinoma with a micropapillary component, an abrupt transition is usually seen between the invasive micropapillary component and conventional adenocarcinoma [
3]. IMPCs are all invariably associated with high aggressiveness, extensive lymphovascular invasion, extensive lymph node metastases, and poor prognosis [
1‐
3]. …