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Archives of Virology

Erschienen in:

01.11.2012 | Original Article

Genome characterization of a novel porcine bocavirus

verfasst von: Wan-zhu Yang, Jie-mei Yu, Jin-song Li, Wei-xia Cheng, Can-ping Huang, Zhao-jun Duan

Erschienen in: Archives of Virology | Ausgabe 11/2012

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Abstract

Using a high-throughput DNA sequencing method, one DNA sequence (contig01006), suspected to belong to a novel porcine bocavirus (PBoV), was found with a high rate of detection (19.6 %) in fecal samples from healthy piglets. Moreover, a novel PBoV (tentatively named PBoV3C) with a nearly complete genome sequence (5235 bp) was identified. PBoV3C exhibits typical genome characteristics of bocaviruses and shows the highest genomic sequence identity (78 % to 81 %) to PBoV3A/B (PBoV3/4-UK) and PBoV3D/E (PBoV3/4-HK), respectively. Phylogenetic and recombination analysis indicated high diversity, prevalence and complexity among the PBoVs. The phospholipase A2 (PLA2) site of VP1 and the secondary structure of VP2 of PBoV3C were also analyzed. Additionally, we propose a uniform method of PBoV nomenclature based on the VP1 gene.

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Titel: Genome characterization of a novel porcine bocavirus
verfasst von: Wan-zhu Yang
Jie-mei Yu
Jin-song Li
Wei-xia Cheng
Can-ping Huang
Zhao-jun Duan
Publikationsdatum: 01.11.2012
Verlag: Springer Vienna
Erschienen in: Archives of Virology / Ausgabe 11/2012
Print ISSN: 0304-8608
Elektronische ISSN: 1432-8798
DOI: https://doi.org/10.1007/s00705-012-1407-7

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