nach oben

Archives of Virology

Erschienen in:

01.11.2014 | Original Article

Genomic and phylogenetic characterization of Shuni virus

verfasst von: Charmaine van Eeden, Frank Harders, Jeroen Kortekaas, Alex Bossers, Marietjie Venter

Erschienen in: Archives of Virology | Ausgabe 11/2014

Einloggen, um Zugang zu erhalten

Abstract

Shuni virus (SHUV), a member of the genus Orthobunyavirus, has in a recent study been associated with neurological disease in horses in South Africa. After its first isolation in 1966 from an asymptomatic bovine, very little attention was given to the genetic characterisation of SHUV. The association of SHUV with severe neurological disease in several horses in South Africa prompted us to determine the full genome sequence of a horse neurovirulent isolate to compare it to other members of the genus Orthobunyavirus, as well as the partially sequenced genome of the prototype SHUV strain. The availability of a full genome sequence will facilitate the development of a reverse genetics system to study SHUV molecular biology and pathogenesis.

Nur mit Berechtigung zugänglich

Moore DL et al (1975) Arthropod-borne viral infections in man in Nigeria: 1964-1970. Ann Trop Med Parasitol 69:49–64PubMed

Causey OR et al (1972) Isolations of Simbu-group viruses in Ibadan, Nigeria 1964-69, including the new types Sango, Shamonda, Sabo and Shuni. Ann Trop Med Parasitol 66(3):357–362PubMed

Goller KV et al (2012) Schmallenberg virus as possible ancestor of Shamonda virus. Emerg Infect Dis 18(10):1644–1646PubMedCrossRefPubMedCentral

van Eeden C et al (2012) Shuni virus as cause of neurologic disease in horses. Emerg Infect Dis 18(2):318–321PubMedCrossRefPubMedCentral

Elliott RM (1990) Molecular biology of the Bunyaviridae. J Gen Virol 71(Pt 3):501–522PubMedCrossRef

Fazakerley JK et al (1988) Organization of the middle RNA segment of snowshoe hare Bunyavirus. Virology 167(2):422–432PubMedCrossRef

Fuller F, Bhown AS, Bishop DH (1983) Bunyavirus nucleoprotein, N, and a non-structural protein, NSS, are coded by overlapping reading frames in the S RNA. J Gen Virol 64(Pt 8):1705–1714PubMedCrossRef

Saeed MF et al (2001) Phylogeny of the Simbu serogroup of the genus Bunyavirus. J Gen Virol 82:2173–2181PubMed

Yanase T et al (2003) Sequence analysis of the medium RNA segment of three Simbu serogroup viruses, Akabane, Aino, and Peaton viruses. Virus Res 93(1):63–69PubMedCrossRef

10.

Ogawa Y et al (2007) Sequence determination and functional analysis of the Akabane virus (family Bunyaviridae) L RNA segment. Arch Virol 152(5):971–979PubMedCrossRef

11.

Briese T et al (2006) Batai and Ngari viruses: M segment reassortment and association with severe febrile disease outbreaks in East Africa. J Virol 80(11):5627–5630PubMedCrossRefPubMedCentral

12.

Yanase T et al (2006) Genetic characterization of Batai virus indicates a genomic reassortment between orthobunyaviruses in nature. Arch Virol 151(11):2253–2260PubMedCrossRef

13.

Kobayashi T et al (2007) Genetic diversity and reassortments among Akabane virus field isolates. Virus Res 130(1–2):162–171PubMedCrossRef

14.

Saeed MF et al (2001) Jatobal virus is a reassortant containing the small RNA of Oropouche virus. Virus Res 77(1):25–30PubMedCrossRef

15.

Yanase T et al (2010) Genetic characterization of Aino and Peaton virus field isolates reveals a genetic reassortment between these viruses in nature. Virus Res 153(1):1–7PubMedCrossRef

16.

Langmead B, Salzberg SL (2012) Fast gapped-read alignment with Bowtie 2. Nat Methods 9(4):357–359PubMedCrossRefPubMedCentral

17.

Jones DT, Taylor WR, Thornton JM (1992) The rapid generation of mutation data matrices from protein sequences. Comput Appl Biosci 8(3):275–282PubMed

18.

Tamura K et al (2011) MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol Biol Evol 28:2731–2739PubMedCrossRefPubMedCentral

19.

Thompson JD, Higgins DG, Gibson TJ (1994) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22(22):4673–4680PubMedCrossRefPubMedCentral

20.

Nei M, Gojobori T (1986) Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions. Mol Biol Evol 3(5):418–426PubMed

21.

Eifan SA, Elliott RM (2009) Mutational analysis of the Bunyamwera orthobunyavirus nucleocapsid protein gene. J Virol 83(21):11307–11317PubMedCrossRefPubMedCentral

22.

Bridgen A et al (2001) Bunyamwera bunyavirus nonstructural protein NSs is a nonessential gene product that contributes to viral pathogenesis. Proc Natl Acad Sci USA 98(2):664–669PubMedCrossRefPubMedCentral

23.

Muller R et al (1995) Characterization of clone 13, a naturally attenuated avirulent isolate of Rift Valley fever virus, which is altered in the small segment. Am J Trop Med Hyg 53(4):405–411PubMed

24.

Varela M et al (2013) Schmallenberg virus pathogenesis, tropism and interaction with the innate immune system of the host. PLoS Pathog 9(1):e1003133PubMedCrossRefPubMedCentral

25.

Briese T, Kapoor V, Lipkin WI (2007) Natural M-segment reassortment in Potosi and Main Drain viruses: implications for the evolution of orthobunyaviruses. Arch Virol 152(12):2237–2247PubMedCrossRef

26.

Briese T, Rambaut A, Lipkin WI (2004) Analysis of the medium (M) segment sequence of Guaroa virus and its comparison to other orthobunyaviruses. J Gen Virol 85(Pt 10):3071–3077PubMedCrossRef

27.

Pollitt E et al (2006) Characterization of Maguari orthobunyavirus mutants suggests the nonstructural protein NSm is not essential for growth in tissue culture. Virology 348(1):224–232PubMedCrossRef

28.

Savji N et al (2011) Genomic and phylogenetic characterization of Leanyer virus, a novel orthobunyavirus isolated in northern Australia. J Gen Virol 92(Pt 7):1676–1687PubMedCrossRefPubMedCentral

29.

Pekosz A et al (1995) Protection from La Crosse virus encephalitis with recombinant glycoproteins: role of neutralizing anti-G1 antibodies. J Virol 69(6):3475–3481PubMedPubMedCentral

30.

Reguera J, Weber F, Cusack S (2010) Bunyaviridae RNA polymerases (L-protein) have an N-terminal, influenza-like endonuclease domain, essential for viral cap-dependent transcription. PLoS Pathog 6(9):e1001101PubMedCrossRefPubMedCentral

31.

Elliott RM, Schmaljohn CS, Collett MS (1991) Bunyaviridae genome structure and gene expression. Curr Top Microbiol Immunol 169:91–141PubMed

32.

Fauquet CM, Fargette D (2005) International Committee on Taxonomy of Viruses and the 3,142 unassigned species. Virol J 2:64PubMedCrossRefPubMedCentral

33.

Barr JN et al (2003) Segment-specific terminal sequences of Bunyamwera bunyavirus regulate genome replication. Virology 311(2):326–338PubMedCrossRef

34.

Barr JN, Wertz GW (2004) Bunyamwera bunyavirus RNA synthesis requires cooperation of 3’- and 5’-terminal sequences. J Virol 78(3):1129–1138PubMedCrossRefPubMedCentral

35.

Kohl A et al (2006) Genetic elements regulating packaging of the Bunyamwera orthobunyavirus genome. J Gen Virol 87(Pt 1):177–187PubMedCrossRef

36.

Akashi H et al (1997) Sequence determination and phylogenetic analysis of the Akabane bunyavirus S RNA genome segment. J Gen Virol 78(Pt 11):2847–2851PubMed

37.

Matsumori Y et al (2002) Serological and genetic characterization of newly isolated Peaton virus in Japan. Brief report. Arch Virol 147(2):401–410PubMedCrossRef

38.

Lee E et al (2000) Mutagenesis of the signal sequence of yellow fever virus prM protein: enhancement of signalase cleavage In vitro is lethal for virus production. J Virol 74(1):24–32PubMedCrossRefPubMedCentral

39.

Botha EM et al (2008) Genetic determinants of virulence in pathogenic lineage 2 west nile virus strains. Emerg Infect Dis 14(2):222–230PubMedCrossRefPubMedCentral

Titel: Genomic and phylogenetic characterization of Shuni virus
verfasst von: Charmaine van Eeden
Frank Harders
Jeroen Kortekaas
Alex Bossers
Marietjie Venter
Publikationsdatum: 01.11.2014
Verlag: Springer Vienna
Erschienen in: Archives of Virology / Ausgabe 11/2014
Print ISSN: 0304-8608
Elektronische ISSN: 1432-8798
DOI: https://doi.org/10.1007/s00705-014-2131-2

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

^{Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag}

Kostenlos registrieren

Neu im Fachgebiet Innere Medizin

Hodgkin Lymphom: BrECADD-Regime übertrifft die Erwartungen

05.06.2024 ASCO 2024 Kongressbericht

Das Kombinationsregime BrECADD mit Brentuximab vedotin ermöglichte in der Studie HD21 beim fortgeschrittenen klassischen Hodgkin-Lymphom eine unerwartet hohe progressionsfreie Überlebensrate von 94,3% nach vier Jahren. Gleichzeitig war das Regime besser tolerabel als der bisherige Standard eBEACOPP.

Antikörper-Drug-Konjugat verdoppelt PFS bei Multiplem Myelom

05.06.2024 ASCO 2024 Nachrichten

Zwei Phase-3-Studien deuten auf erhebliche Vorteile des Antikörper-Wirkstoff-Konjugats Belantamab-Mafodotin bei vorbehandelten Personen mit Multiplem Myelom: Im Vergleich mit einer Standard-Tripeltherapie wurde das progressionsfreie Überleben teilweise mehr als verdoppelt.

Neuer TKI gegen CML: Höhere Wirksamkeit, seltener Nebenwirkungen

05.06.2024 Chronische myeloische Leukämie Nachrichten

Der Tyrosinkinasehemmer (TKI) Asciminib ist älteren Vertretern dieser Gruppe bei CML offenbar überlegen: Personen mit frisch diagnostizierter CML entwickelten damit in einer Phase-3-Studie häufiger eine gut molekulare Response, aber seltener ernste Nebenwirkungen.

Hereditäres Angioödem: Tablette könnte Akuttherapie erleichtern

05.06.2024 Hereditäres Angioödem Nachrichten

Medikamente zur Bedarfstherapie bei hereditärem Angioödem sind bisher nur als Injektionen und Infusionen verfügbar. Der Arzneistoff Sebetralstat kann oral verabreicht werden und liefert vielversprechende Daten.

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 11/2014

Identification and amplification of Japanese encephalitis virus and Getah virus propagated from a single porcine serum sample: a case of coinfection

Insights into new bacteriophages of Lactococcus garvieae belonging to the family Podoviridae

Genetic and antigenic evolution of H9N2 avian influenza viruses circulating in Egypt between 2011 and 2013

Single-nucleotide polymorphisms and reading frame shifts in RNA2 recombinant regions of tobacco rattle virus isolates Slu24 and Deb57

Luteovirus: insights into pathogenicity