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Erschienen in: InFo Hämatologie + Onkologie 5/2018

10.09.2018 | Herzinsuffizienz | fortbildung

Auftreten, Risiken, Prävention und Management

Kardiotoxizität antineoplastischer Substanzen

verfasst von: Dr. med. Antonia Beitzen-Heineke, Dirk Westermann, Carsten Bokemeyer

Erschienen in: InFo Hämatologie + Onkologie | Ausgabe 5/2018

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Zusammenfassung

Durch verbesserte Therapieoptionen steigt die Lebenserwartung von Krebspatienten. Das führt dazu, dass immer mehr Patienten mögliche kardiovaskuläre Nebenwirkungen ihrer antitumoralen Therapie erleben. Auch die Vielzahl neuer antineoplastischer Substanzen mit unterschiedlichsten Wirkmechanismen trägt zu einer zunehmenden Komplexität potenzieller kardiovaskulärer Komplikationen bei. In dieser Arbeit finden Sie eine Überblick zu relevanten kardiotoxischen Nebenwirkungen häufig eingesetzter Tumortherapeutika sowie Empfehlungen zur Prävention und zum Management.
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Metadaten
Titel
Auftreten, Risiken, Prävention und Management
Kardiotoxizität antineoplastischer Substanzen
verfasst von
Dr. med. Antonia Beitzen-Heineke
Dirk Westermann
Carsten Bokemeyer
Publikationsdatum
10.09.2018
Verlag
Springer Medizin
Erschienen in
InFo Hämatologie + Onkologie / Ausgabe 5/2018
Print ISSN: 2662-1754
Elektronische ISSN: 2662-1762
DOI
https://doi.org/10.1007/s15004-018-6180-7

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Dapagliflozin ist nun zur Behandlung aller Patient:innen mit chronischer symptomatischer Herzinsuffizienz zugelassen und bietet somit auch neue Hoffnung für die Therapie von jenen mit HFpEF. In der DELIVER-Studie zeigte der SGLT-2-Inhibitor eine signifikante Reduktion von Herzinsuffizienz-Hospitalisierungen und CV-Todesfällen.

ANZEIGE

ACS-Erstlinientherapie: Konsensbeschluss rät zur DAPT mit Ticagrelor

Ein Konsortium führender Fachgesellschaften erarbeitete jüngst auf Basis umfangreicher Metaanalysen einen Konsens für die Therapie koronarer Herzkrankheiten. Was dabei auffiel: Die duale Plättchenhemmung (DAPT) mit Ticagrelor ist die bevorzugte Therapieoption für das akute Koronarsyndrom (ACS).