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Erschienen in:

01.06.2015

Identifying decreased peristalsis of abnormal small bowel segments in Crohn’s disease using cine MR enterography: the frozen bowel sign

verfasst von: Flavius F. Guglielmo, Donald G. Mitchell, Patrick L. O’Kane, Sandeep P. Deshmukh, Christopher G. Roth, Ilene Burach, Aaron Burns, Susan Dulka, Laurence Parker

Erschienen in: Abdominal Radiology | Ausgabe 5/2015

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Abstract

Purpose

The purpose of this study was to evaluate whether affected bowel in Crohn’s disease patients can be identified by observing decreased peristalsis (frozen bowel sign) using cine balanced steady-state free precession (cine BSSFP) images.

Materials and methods

5 radiologists independently reviewed cine BSSFP sequences from randomized MR Enterography (MRE) exams for 30 normal and 30 Crohn’s disease patients, graded overall small bowel peristalsis from slowest to fastest, and graded peristalsis for the most abnormal small bowel segment. Sensitivity and specificity of the frozen bowel sign for diagnosing Crohn’s disease were calculated. T tests of the peristalsis difference between abnormal segments and overall small bowel were conducted.

Results

For 5 readers, the sensitivity and specificity of cine BSSFP of the frozen bowel sign for diagnosing Crohn’s disease ranged from 70% to 100% and 87% to 100%, respectively. There were significant differences in peristalsis between abnormal small bowel segments and the overall small bowel for Crohn’s patients, but not in the overall small bowel between normal-MRE patients and Crohn’s disease patients.

Conclusion

Abnormal Crohn’s small bowel segments have significantly decreased peristalsis compared to normal small bowel, which can be identified using cine BSSFP sequences as the frozen bowel sign.

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Titel: Identifying decreased peristalsis of abnormal small bowel segments in Crohn’s disease using cine MR enterography: the frozen bowel sign
verfasst von: Flavius F. Guglielmo
Donald G. Mitchell
Patrick L. O’Kane
Sandeep P. Deshmukh
Christopher G. Roth
Ilene Burach
Aaron Burns
Susan Dulka
Laurence Parker
Publikationsdatum: 01.06.2015
Verlag: Springer US
Erschienen in: Abdominal Radiology / Ausgabe 5/2015
Print ISSN: 2366-004X
Elektronische ISSN: 2366-0058
DOI: https://doi.org/10.1007/s00261-014-0258-y

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Identifying decreased peristalsis of abnormal small bowel segments in Crohn’s disease using cine MR enterography: the frozen bowel sign