Introduction
Methods
Participants
Dementia ascertainment process
Phase 1: Electronic Health Record (EHR) review
Case vignettes
Phase 2: Home visits
Phase 3: consensus diagnostic review board
Probable Dementia ANY of the following (without opposing evidence from same/other source): | Possible Dementia ANY of the following (without opposing evidence from same/other source): |
---|---|
- dementia diagnosis on death certificate (any part) | - recorded cognitive impairment on death certificate |
- dementia diagnosed on clinical review (ICD-11/DSM-5) | - cognitive impairment/decline recorded in notes, but incomplete evidence to meet ICD-11 diagnostic criteria |
- dementia diagnosis in electronic health records | - possibility of dementia recorded in notes but no formal diagnosis/ incomplete evidence to meet ICD-11 diagnostic criteria |
- ICD-11 criteria for dementia diagnosis met by data within any existing records |
Person-hours calculation
Analysis
Results
Participants
Dementia prevalence
No Dementia (n = 747) | Dementia (n = 118) | ||
---|---|---|---|
Sex | Female (%) | 362 (48.5) | 55 (46.6) |
Male (%) | 385 (51.5) | 63 (53.4) | |
Education, years | Mean (SD) | 10.8 (1.1) | 10.6 (1.1) |
Age 11 IQ | Mean (SD) | 101.0 (15.0) | 98.5 (17.2) |
Previous occupation | Manual | 148 (20.2) | 27 (23.5) |
Non-manual | 586 (79.8) | 88 (76.5) | |
Marital Status | Married | 523 (70.0) | 92 (78.0) |
Not married | 224 (30.0) | 26 (22.0) |
Age-stratified dementia prevalence
Age group, years | Alive with dementia | ||||||||
---|---|---|---|---|---|---|---|---|---|
Alive N (%) | Prevalence (per 1000) | Total (N) | Men (N) | Women (N) | Total (%) | Men (%) | Women (%) | P-value | |
65–74.9 | 839 (96.9%) | 8.3 | 7 | 4 | 3 | 0.8% | 0.9% | 0.7% | 0.80 |
75–79.9 | 736 (85.1%) | 44.8 | 33 | 15 | 18 | 4.5% | 4.1% | 4.9% | 0.39 |
80–84.9 | 570 (65.9%) | 94.7 | 54 | 25 | 29 | 9.5% | 9.3% | 9.7% | 0.77 |
85–89.9a | 544 (62.9%) | 99.3 | 54 | 22 | 32 | 9.9% | 8.7% | 11.0% | 0.10 |
Age-stratified dementia incidence
Age group, years | New dementia diagnoses | |||||||
---|---|---|---|---|---|---|---|---|
Incidence Rate (per 1000) | Total (N) | Men (N) | Women (N) | Total (%)a | Men (%) | Women (%) | P-value | |
65–74.9 | 8.3 | 7 | 4 | 3 | 0.8% | 0.9% | 0.7% | 0.62 |
75–79.9 | 48.9 | 36 | 20 | 16 | 4.9% | 5.4% | 4.4% | 0.31 |
80–84.9 | 107.0 | 61 | 32 | 29 | 10.7% | 11.9% | 9.7% | 0.13 |
85–89.9b | 23.9 | 13 | 6 | 7 | 2.4% | 2.4% | 2.4% | 1.00 |
Total | - | 118 | 63 | 55 | - | - | - |
Dementia subtypes
Dementia Subtypea | N | % |
---|---|---|
Dementia Due to Alzheimer Disease | 58 | 49.2 |
Alzheimer Disease Dementia, Mixed Type, with Cerebrovascular Disease (Mixed Dementia) | 20 | 17.0 |
Dementia, Unknown or Unspecified Cause | 19 | 16.1 |
Dementia Due to Cerebrovascular Disease (Vascular Dementia) | 10 | 8.5 |
Dementia Due to Diseases Classified Elsewhere | 5 | 4.2 |
Dementia Due to Lewy Body Disease | 4 | 3.4 |
Dementia Due to Psychoactive Substances including Medicationsb | 2 | 1.7 |
Frontotemporal Dementia | 0 | 0.0 |
Dementia, Other Specified Cause | 0 | 0.0 |
Total | 118 | 100.0% |