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06.02.2016 | Neuro

Image quality, radiation dose and diagnostic accuracy of 70 kVp whole brain volumetric CT perfusion imaging: a preliminary study

verfasst von: Xiao Kun Fang, Qian Qian Ni, U. Joseph Schoepf, Chang Sheng Zhou, Guo Zhong Chen, Song Luo, Stephen R. Fuller, Carlo N. De Cecco, Long Jiang Zhang, Guang Ming Lu

Erschienen in: European Radiology | Ausgabe 11/2016

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Abstract

Purpose

To evaluate image quality and diagnostic accuracy for acute infarct detection and radiation dose of 70 kVp whole brain CT perfusion (CTP) and CT angiography (CTA) reconstructed from CTP source data.

Methods

Patients were divided into three groups (n = 50 each): group A, 80 kVp, 21 scanning time points; groups B, 70 kVp, 21 scanning time points; group C, 70 kVp, 17 scanning time points. Objective and subjective image quality of CTP and CTA were compared. Diagnostic accuracy for detecting acute infarct and cerebral artery stenosis ≥ 50 % was calculated for CTP and CTA with diffusion weighted imaging and digital subtraction angiography as reference standards. Effective radiation dose was compared.

Results

There were no differences in any perfusion parameter value between three groups (P > 0.05). No difference was found in subjective image quality between three groups (P > 0.05). Diagnostic accuracy for detecting acute infarct and vascular stenosis showed no difference between three groups (P > 0.05). Compared with group A, radiation doses of groups B and C were decreased by 28 % and 37 % (both P < 0.001), respectively.

Conclusion

Compared with 80 kVp protocol, 70 kVp brain CTP allows comparable vascular and perfusion assessment and lower radiation dose while maintaining high diagnostic accuracy in detecting acute infarct.

Key Points

• 70 kVp whole brain CTP can provide diagnostic image quality.

• 70 kVp CTP diagnostic accuracy was maintained vs. 80 kVp protocol.

• 70 kVp CTP radiation doses were lower than 80 kVp protocol.

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Titel: Image quality, radiation dose and diagnostic accuracy of 70 kVp whole brain volumetric CT perfusion imaging: a preliminary study
verfasst von: Xiao Kun Fang
Qian Qian Ni
U. Joseph Schoepf
Chang Sheng Zhou
Guo Zhong Chen
Song Luo
Stephen R. Fuller
Carlo N. De Cecco
Long Jiang Zhang
Guang Ming Lu
Publikationsdatum: 06.02.2016
Verlag: Springer Berlin Heidelberg
Erschienen in: European Radiology / Ausgabe 11/2016
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-016-4225-6

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Image quality, radiation dose and diagnostic accuracy of 70 kVp whole brain volumetric CT perfusion imaging: a preliminary study

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Purpose

Methods

Results

Conclusion

Key Points

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