Background
Methods
Patients
Cardiovascular magnetic resonance
ECV quantification
Histology
Statistical analysis
Results
Clinical characteristics
SCLS acute intermittent | SCLS chronic | Controls | |
---|---|---|---|
Number | 20 | 6 | 30 |
Age (y)a
| 51 (40–70) | 44 (31–64) | 52 (32–77) |
Male/Female | 13/20 | 1/6 | 14/30 |
Height (cm)b
| 172 (11) | 162 (11) | 170 (10) |
Weight (kg)b
| 80 (4) | 89 (19) | 81 (19) |
Body surface area (m2)b
| 2 (0.2) | 2 (0.3) | 2 (0.2) |
Body mass index (kg/m2)b
| 27 (4) | 33 (5) | 28 (5) |
Hematocritb
| 42 (6) | 39 (4) | 40 (3) |
Serum creatinine (mg/dL)b
| 0.9 (0.2) | 0.9 (0.3) | 1 (0.2) |
Creatinine clearance (mL/min)b,c
| 105 (36) | 129 (30) | 93 (34) |
Glomerular filtration rate (mL/min/1.73 m2)b,d
| 86 (5) | 85 (38) | 71 (15) |
CMR findings
SCLS acute intermittent | SCLS chronic | Controls | |
---|---|---|---|
Left Ventricular (LV) ejection fraction (%)a
| 62 (5) | 66 (8) | 64 (5) |
LV end diastolic volume (mL)a
| 145 (36) | 153 (23) | 144 (33) |
LV end systolic volume (mL)a
| 56 (17) | 54 (19) | 52 (16) |
LV mass (g)a
| 103 (26) | 88 (17) | 90 (28) |