Skip to main content
Erschienen in: European Archives of Oto-Rhino-Laryngology 11/2019

26.07.2019 | Head and Neck

Indications and results of extended total laryngectomy with en-bloc resection of overlying cervical skin

verfasst von: Xavier León, Montserrat López, Jacinto García, Maria Casasayas, Carlota Rovira, Miquel Quer

Erschienen in: European Archives of Oto-Rhino-Laryngology | Ausgabe 11/2019

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Extended total laryngectomy with en-bloc resection of overlying cervical skin (ETL) is indicated in cases with infiltration of the pre-laryngeal soft tissues. The present study analyses the surgical indications and the results of ETL in our hospital.

Methods

Retrospective review of 38 patients treated with an ETL during the period 1988–2016.

Results

The indications for ETL were the initial treatment of tumors with extralaryngeal extension (n = 16), salvage treatment after failure of partial surgery or radiotherapy (n = 17), and total laryngectomy in patients with infection or fibrosis of the skin over the larynx (n = 5). The surgical defect was reconstructed with local flaps in 3 cases, with pectoralis major flaps in 34 cases, and with an internal mammary artery perforator flap in one case. The rate of pharyngocutaneous fistula in the postoperative period was 16%. 5-year cancer-specific survival for patients treated with an ETL was 67.1%. The patients with positive margins and those operated as a salvage treatment after failure of previous treatments showed worse survival.

Conclusions

ETL offers acceptable oncological results for patients with tumors with extralaryngeal extension. Myocutaneous or myofascial pectoralis major flaps allow for adequate reconstruction of the surgical defect with a low rate of complications.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat García Lorenzo J, Montoro Martínez V, Rigo Quera A, Codina Aroca A, López Vilas M, Quer Agustí M, León Vintró X (2017) Modifications in the treatment of advanced laryngeal cancer throughout the last 30 years. Eur Arch Otorhinolaryngol 274:3449–3455CrossRef García Lorenzo J, Montoro Martínez V, Rigo Quera A, Codina Aroca A, López Vilas M, Quer Agustí M, León Vintró X (2017) Modifications in the treatment of advanced laryngeal cancer throughout the last 30 years. Eur Arch Otorhinolaryngol 274:3449–3455CrossRef
2.
Zurück zum Zitat Olsen KD (2010) Reexamining the treatment of advanced laryngeal cancer. Head Neck 32:1–7PubMed Olsen KD (2010) Reexamining the treatment of advanced laryngeal cancer. Head Neck 32:1–7PubMed
3.
Zurück zum Zitat Ampil FL, Nathan CO, Caldito G, Lian TF, Aarstad RF, Krishnamsetty RM (2004) Total laryngectomy and postoperative radiotherapy for T4 laryngeal cancer: a 14-year review. Am J Otolaryngol 25:88–93CrossRef Ampil FL, Nathan CO, Caldito G, Lian TF, Aarstad RF, Krishnamsetty RM (2004) Total laryngectomy and postoperative radiotherapy for T4 laryngeal cancer: a 14-year review. Am J Otolaryngol 25:88–93CrossRef
4.
Zurück zum Zitat Agra IM, Ferlito A, Takes RP, Silver CE, Olsen KD, Stoeckli SJ et al (2012) Diagnosis and treatment of recurrent laryngeal cancer following initial nonsurgical therapy. Head Neck 34:727–735CrossRef Agra IM, Ferlito A, Takes RP, Silver CE, Olsen KD, Stoeckli SJ et al (2012) Diagnosis and treatment of recurrent laryngeal cancer following initial nonsurgical therapy. Head Neck 34:727–735CrossRef
5.
Zurück zum Zitat Guerrier Y (1987) Les laryngectomies totales élargies. In: Traité de technique chirurgicale O.R.L. et cervico-faciale, vol 3. Masson, Paris, pp 331–339 Guerrier Y (1987) Les laryngectomies totales élargies. In: Traité de technique chirurgicale O.R.L. et cervico-faciale, vol 3. Masson, Paris, pp 331–339
6.
Zurück zum Zitat Croce A, Moretti A, Bianchedi M, Neri G, Falcone G (1995) Widened forwarding total laryngectomy ("squared laryngectomy"). Hints of surgical techniques and personal experience. Acta Otorhinolaryngol Ital 15:355–360PubMed Croce A, Moretti A, Bianchedi M, Neri G, Falcone G (1995) Widened forwarding total laryngectomy ("squared laryngectomy"). Hints of surgical techniques and personal experience. Acta Otorhinolaryngol Ital 15:355–360PubMed
7.
Zurück zum Zitat León X, Orús C, Quer M (2002) Design, maintenance, and exploitation of an oncologic database for patients with malignant tumors of the head and neck. Acta Otorrinolaringol Esp 53:185–190CrossRef León X, Orús C, Quer M (2002) Design, maintenance, and exploitation of an oncologic database for patients with malignant tumors of the head and neck. Acta Otorrinolaringol Esp 53:185–190CrossRef
8.
Zurück zum Zitat Lam KH (1983) Extralaryngeal spread of cancer of the larynx: a study with whole-organ sections. Head Neck Surg 5:410–424CrossRef Lam KH (1983) Extralaryngeal spread of cancer of the larynx: a study with whole-organ sections. Head Neck Surg 5:410–424CrossRef
9.
Zurück zum Zitat Beitler JJ, Muller S, Grist WJ, Corey A, Klein AM, Johns MM et al (2010) Prognostic accuracy of computed tomography findings for patients with laryngeal cancer undergoing laryngectomy. J Clin Oncol 28:2318–2322CrossRef Beitler JJ, Muller S, Grist WJ, Corey A, Klein AM, Johns MM et al (2010) Prognostic accuracy of computed tomography findings for patients with laryngeal cancer undergoing laryngectomy. J Clin Oncol 28:2318–2322CrossRef
10.
Zurück zum Zitat Chen SA, Muller S, Chen AY, Hudgins PA, Shin DM, Khuri F, Saba NF, Beitler JJ (2011) Patterns of extralaryngeal spread of laryngeal cancer: thyroid cartilage penetration occurs in a minority of patients with extralaryngeal spread of laryngeal squamous cell cancers. Cancer 117:5047–5051CrossRef Chen SA, Muller S, Chen AY, Hudgins PA, Shin DM, Khuri F, Saba NF, Beitler JJ (2011) Patterns of extralaryngeal spread of laryngeal cancer: thyroid cartilage penetration occurs in a minority of patients with extralaryngeal spread of laryngeal squamous cell cancers. Cancer 117:5047–5051CrossRef
11.
Zurück zum Zitat Gallo A, Moi R, Simonelli M, Vitolo D, Fiorella ML, Marvaso V, Manciocco V, de Vincentiis M (2001) Salvage resection after previous laryngeal surgery: total laryngectomy with en bloc resection of the overlying cervical skin. Arch Otolaryngol Head Neck Surg 127:786–789PubMed Gallo A, Moi R, Simonelli M, Vitolo D, Fiorella ML, Marvaso V, Manciocco V, de Vincentiis M (2001) Salvage resection after previous laryngeal surgery: total laryngectomy with en bloc resection of the overlying cervical skin. Arch Otolaryngol Head Neck Surg 127:786–789PubMed
12.
Zurück zum Zitat Mosleh M, Fathy H (2014) Advanced laryngeal cancer with skin infiltration: survival analysis. Egypt J Otolaryngol 30:122–125CrossRef Mosleh M, Fathy H (2014) Advanced laryngeal cancer with skin infiltration: survival analysis. Egypt J Otolaryngol 30:122–125CrossRef
13.
Zurück zum Zitat Zahran M, Youssef A (2018) The role of regional flaps in locally advanced cancer larynx with skin invasion Egypt. J Otolaryngol 34:289–292 Zahran M, Youssef A (2018) The role of regional flaps in locally advanced cancer larynx with skin invasion Egypt. J Otolaryngol 34:289–292
14.
Zurück zum Zitat Emerick KS, Herr MA, Deschler DG (2014) Supraclavicular flap reconstruction following total laryngectomy. Laryngoscope 124:1777–1782CrossRef Emerick KS, Herr MA, Deschler DG (2014) Supraclavicular flap reconstruction following total laryngectomy. Laryngoscope 124:1777–1782CrossRef
15.
Zurück zum Zitat Schellekens PP, Paes EC, Hage JJ, van der Wal MB, Bleys RL, Kon M (2011) Anatomy of the vascular pedicle of the internal mammary artery perforator (IMAP) flap as applied for head and neck reconstruction. J Plast Reconstr Aesthet Surg 64:53–57CrossRef Schellekens PP, Paes EC, Hage JJ, van der Wal MB, Bleys RL, Kon M (2011) Anatomy of the vascular pedicle of the internal mammary artery perforator (IMAP) flap as applied for head and neck reconstruction. J Plast Reconstr Aesthet Surg 64:53–57CrossRef
16.
Zurück zum Zitat Chiesa Estomba CM, González García JA, Sistiaga Suarez JA, Thomas Arrizabalaga I, Larruscain Sarasola E, Altuna Mariezcurrena X (2018) Efficacy of the myofascial pectoralis major flap in the reduction of salivary fistulas after salvage total laryngectomy. Acta Otorrinolaringol Esp 69:99–104CrossRef Chiesa Estomba CM, González García JA, Sistiaga Suarez JA, Thomas Arrizabalaga I, Larruscain Sarasola E, Altuna Mariezcurrena X (2018) Efficacy of the myofascial pectoralis major flap in the reduction of salivary fistulas after salvage total laryngectomy. Acta Otorrinolaringol Esp 69:99–104CrossRef
17.
Zurück zum Zitat Casasayas M, Sansa A, García-Lorenzo J, López M, Orús C, Peláez X, Quer M, León X (2019) Pharyngocutaneous fistula after total laryngectomy: multivariate analysis of risk factors and a severity-based classification proposal. Eur Arch Otorhinolaryngol 276:143–151CrossRef Casasayas M, Sansa A, García-Lorenzo J, López M, Orús C, Peláez X, Quer M, León X (2019) Pharyngocutaneous fistula after total laryngectomy: multivariate analysis of risk factors and a severity-based classification proposal. Eur Arch Otorhinolaryngol 276:143–151CrossRef
Metadaten
Titel
Indications and results of extended total laryngectomy with en-bloc resection of overlying cervical skin
verfasst von
Xavier León
Montserrat López
Jacinto García
Maria Casasayas
Carlota Rovira
Miquel Quer
Publikationsdatum
26.07.2019
Verlag
Springer Berlin Heidelberg
Erschienen in
European Archives of Oto-Rhino-Laryngology / Ausgabe 11/2019
Print ISSN: 0937-4477
Elektronische ISSN: 1434-4726
DOI
https://doi.org/10.1007/s00405-019-05573-8

Weitere Artikel der Ausgabe 11/2019

European Archives of Oto-Rhino-Laryngology 11/2019 Zur Ausgabe

Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

Insektenstiche sind bei Erwachsenen die häufigsten Auslöser einer Anaphylaxie. Einen wirksamen Schutz vor schweren anaphylaktischen Reaktionen bietet die allergenspezifische Immuntherapie. Jedoch kommt sie noch viel zu selten zum Einsatz.

HNO-Op. auch mit über 90?

16.04.2024 HNO-Chirurgie Nachrichten

Mit Blick auf das Risiko für Komplikationen nach elektiven Eingriffen im HNO-Bereich scheint das Alter der Patienten kein ausschlaggebender Faktor zu sein. Entscheidend ist offenbar, wie fit die Betroffenen tatsächlich sind.

Intrakapsuläre Tonsillektomie gewinnt an Boden

16.04.2024 Tonsillektomie Nachrichten

Gegenüber der vollständigen Entfernung der Gaumenmandeln hat die intrakapsuläre Tonsillektomie einige Vorteile, wie HNO-Fachleute aus den USA hervorheben. Sie haben die aktuelle Literatur zu dem Verfahren gesichtet.

Bilateraler Hörsturz hat eine schlechte Prognose

15.04.2024 Hörsturz Nachrichten

Die Mehrzahl der Menschen mit Hörsturz ist einseitig betroffen, doch auch ein beidseitiger Hörsturz ist möglich. Wie häufig solche Fälle sind und wie sich ihr Verlauf darstellt, hat eine HNO-Expertenrunde aus den USA untersucht.

Update HNO

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert – ganz bequem per eMail.