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International Journal of Mental Health and Addiction

Erschienen in:

13.10.2020 | Original Article

Initial Heroin Use Patterns Predict 5-Year Relapse: Results from a Longitudinal Cohort Study in Shanghai, China

verfasst von: Ruihua Li, Tianzhen Chen, Haifeng Jiang, Na Zhong, Jiang Du, Zhibin Li, Yan Zhao, Haiming Sun, Zhikang Chen, Chuanwei Li, Min Zhao

Erschienen in: International Journal of Mental Health and Addiction | Ausgabe 2/2022

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Abstract

People start to use heroin in different patterns. This study identified three initial heroin use patterns in a heroin use cohort: No-factor initial pattern (with no factors of initial heroin use), Single-factor initial pattern (with 1 of 3 factors of initial heroin use), and Multiple-factor initial pattern (with 2 or 3 factors of initial heroin use). The cumulative heroin relapse rate was 53.3%, 62.4%, and 72.7% respectively for No-factor, Single-factor, and Multiple-factor initial patterns during the 5-year follow-up. The adjusted hazard ratio (AHR) was 1.401 (95% CI: 1.091–1.799, p = 0.008) in Single-factor initial pattern and 2.381 (95% CI: 1.546–3.668, p < 0.001) in Multiple-factor initial pattern compared to No-factor initial pattern. This study added new evidence to the impact of initial heroin use on long-term relapse risk, which suggested that initial heroin use patterns should not be neglected.

Bossert, J. M., Ghitza, U. E., Lu, L., Epstein, D. H., & Shaham, Y. (2005). Neurobiology of relapse to heroin and cocaine seeking: an update and clinical implications. European Journal of Pharmacology, 526(1–3), 36–50.CrossRef

Cui, S., Li, Y., Xiang, Y. T., Yan, K. J., Fan, C., Chen, Q., Du, W., Zhang, G., Xiao, L., Li, Y., Yuan, X., Xie, K., & Luo, X. (2015). Demographic and clinical features of Chinese heroin users who switch from non-injection to injection. Substance Use & Misuse, 50(14), 1739–1746.CrossRef

Chalana, H., Kundal, T., Gupta, V., & Malhari, A. S. (2016). Predictors of relapse after inpatient opioid detoxification during 1-year follow-up. Journal of Addiction, 2016, 7620860.CrossRef

Crouse, J. J., Chitty, K. M., Iorfino, F., White, D., Nichles, A., Zmicerevska, N., Guastella, A. J., Moustafa, A. A., Hermens, D. F., Scott, E. M., & Hickie, I. B. (2019). Exploring associations between early substance use and longitudinal socio-occupational functioning in young people engaged in a mental health service. PLoS One, 14(1), e0210877.CrossRef

Chen, T., Zhong, N., Du, J., Li, Z., Zhao, Y., Sun, H., Chen, Z., Jiang, H., Zhao, M., (2019). Polydrug use patterns and their impact on relapse among heroin-dependent patients in Shanghai, China. Addiction 2019;114(2):259–267.

China National Narcotics Control Commission. http://www.nncc626.com/2019-06/17/c_1210161797.htm Last accessed on 2020.06.02.

Darke, S., & Hall, W. (2003). Heroin overdose: Research and evidence-based intervention. Journal of Urban Health: Bulletin of the New York Academy of Medicine, 80(2), 189–200.CrossRef

Debeck, K., Kerr, T., Marshall, B. D., Simo, A., Montaner, J., & Wood, E. (2013). Risk factors for progression to regular injection drug use among street-involved youth in a Canadian setting. Drug and Alcohol Dependence, 133(2), 468–472.CrossRef

Degenhardt, L., Peacock, A., Colledge, S., Leung, J., Grebely, J., Vickerman, P., Stone, J., Cunningham, E. B., Trickey, A., Dumchev, K., Lynskey, M., Griffiths, P., Mattick, R. P., Hickman, M., & Larney, S. (2017). Global prevalence of injecting drug use and sociodemographic characteristics and prevalence of HIV, HBV, and HCV in people who inject drugs: a multistage systematic review. The Lancet. Global Health, 5(12), e1192–e1207.CrossRef

Ding, Y., He, N., & Detels, R. (2013). Circumstances of initiation into new-type drug use among adults in Shanghai: are there differences by types of first new-type drug used? Drug and Alcohol Dependence, 131(3), 278–283.CrossRef

Hser, Y. I., Evans, E., Grella, C., Ling, W., & Anglin, D. (2015). Long-term course of opioid addiction. Harvard Review of Psychiatry, 23(2), 76–89.CrossRef

Hines, L. A., Lynskey, M., Morley, K. I., Griffiths, P., Gossop, M., Powis, B., & Strang, J. (2017). The relationship between initial route of heroin administration and speed of transition to daily heroin use. Drug and Alcohol Review, 36(5), 633–638.CrossRef

Li, X., Zhou, Y., & Stanton, B. (2002). Illicit drug initiation among institutionalized drug users in China. Addiction, 97(5), 575–582.CrossRef

Lorvick, J., Browne, E. N., Lambdin, B. H., & Comfort, M. (2018). Polydrug use patterns, risk behavior and unmet healthcare need in a community-based sample of women who use cocaine, heroin or methamphetamine. Addictive Behaviors, 85, 94–99.CrossRef

Ledgerwood, D. M., Lister, J. J., LaLiberte, B., Lundahl, L. H., & Greenwald, M. K. (2019). Injection opioid use as a predictor of treatment outcomes among methadone-maintained opioid-dependent patients. Addictive Behaviors, 90, 191–195.CrossRef

Mills, K. L., Teesson, M., Darke, S., Ross, J., & Lynskey, M. (2004). Young people with heroin dependence: findings from the Australian Treatment Outcome Study (ATOS). Journal of Substance Abuse Treatment, 27(1), 67–73.CrossRef

Nutt, D., King, L. A., Saulsbury, W., & Blakemore, C. (2007). Development of a rational scale to assess the harm of drugs of potential misuse. Lancet, 369(9566), 1047–1053.CrossRef

Pattij, T., & De Vries, T. J. (2013). The role of impulsivity in relapse vulnerability. Current Opinion in Neurobiology, 23(4), 700–705.CrossRef

Pagano, M. E., Wang, A. R., Rowles, B. M., Lee, M. T., & Johnson, B. R. (2015). Social anxiety and peer helping in adolescent addiction treatment. Alcoholism, Clinical and Experimental Research, 39(5), 887–895.CrossRef

Rong, C., Jiang, H. F., Zhang, R. W., Zhang, L. J., Zhang, J. C., Zhang, J., & Feng, X. S. (2016). Factors associated with relapse among heroin addicts: evidence from a two-year community-based follow-up study in China. International Journal of Environmental Research and Public Health, 13(2), 177.CrossRef

Roy, É., Arruda, N., Bruneau, J., & Jutras-Aswad, D. (2016). Epidemiology of injection drug use: new trends and prominent issues. Canadian journal of psychiatry. Revue canadienne de psychiatrie, 61(3), 136–144.

Smyth, B. P., Barry, J., Keenan, E., & Ducray, K. (2010). Lapse and relapse following inpatient treatment of opiate dependence. Irish Medical Journal, 103(6), 176–179.PubMed

Su, H., Li, Z., Du, J., Jiang, H., Chen, Z., Sun, H., Zhao, M., (2015). Predictors of heroin relapse: personality traits, impulsivity, COMT gene Val158met polymorphism in a 5-year prospective study in Shanghai, China. American journal of medical genetics. Part B, Neuropsychiatric genetics: the official publication of the International Society of Psychiatric Genetics 168(8), 712–719.

Sharma, B., Bruner, A., Barnett, G., & Fishman, M. (2016). Opioid use disorders. Child and Adolescent Psychiatric Clinics of North America, 25(3), 473–487.CrossRef

Su, S., Mao, L., Zhao, J., Chen, L., Jing, J., Cheng, F., & Zhang, L. (2018). Epidemics of HIV, HCV and syphilis infection among synthetic drugs only users, heroin-only users and poly-drug users in Southwest China. Scientific Reports, 8(1), 6615.CrossRef

Su, S., Fairley, C. K., Mao, L., Medland, N. A., Jing, J., Cheng, F., & Zhang, L. (2019). Estimates of the national trend of drugs use during 2000-2030 in China: a population-based mathematical model. Addictive Behaviors, 93, 65–71.CrossRef

Teesson, M., Marel, C., Darke, S., Ross, J., Slade, T., Burns, L., Lynskey, M., Memedovic, S., White, J., & Mills, K. L. (2017). Trajectories of heroin use: 10-11-year findings from the Australian treatment outcome study. Addiction (Abingdon, England), 112(6), 1056–1068.CrossRef

United Nations Office on Drugs and Crime. (2019). World drug report (2019). New York: United Nations.CrossRef

Wang, Z., Li, W. X., & Zhi-Min, L. (2017). Similarity and difference in drug addiction process between heroin- and methamphetamine-dependent users. Substance Use & Misuse, 52(4), 459–467.CrossRef

Zhang, D., Shao, C., Shao, M., Yan, P., Wang, Y., Liu, Y., Liu, W., Lin, T., Xie, Y., Zhao, Y., Lu, D., Li, Y., & Jin, L. (2007). Effect of mu-opioid receptor gene polymorphisms on heroin-induced subjective responses in a Chinese population. Biological Psychiatry, 61(11), 1244–1251.CrossRef

Zhou, Y., Luo, W., Cao, X. B., Zhang, B., & Wu, Z. Y. (2016). Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, 37(5), 648–652.

Zhong, B. L., Xie, W. X., Zhu, J. H., Lu, J., & Chen, H. (2019). Prevalence and correlates of suicide attempt among Chinese individuals receiving methadone maintenance treatment for heroin dependence. Scientific Reports, 9(1), 15859.CrossRef

Titel: Initial Heroin Use Patterns Predict 5-Year Relapse: Results from a Longitudinal Cohort Study in Shanghai, China
verfasst von: Ruihua Li
Tianzhen Chen
Haifeng Jiang
Na Zhong
Jiang Du
Zhibin Li
Yan Zhao
Haiming Sun
Zhikang Chen
Chuanwei Li
Min Zhao
Publikationsdatum: 13.10.2020
Verlag: Springer US
Erschienen in: International Journal of Mental Health and Addiction / Ausgabe 2/2022
Print ISSN: 1557-1874
Elektronische ISSN: 1557-1882
DOI: https://doi.org/10.1007/s11469-020-00407-9

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