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Erschienen in: Pediatric Radiology 9/2012

01.09.2012 | Original Article

Injection of gadolinium contrast through pediatric central venous catheters: a safety study

verfasst von: John M. Moriarty, Geoffrey L. Kung, Yanerys Ramos, Abbas N. Moghaddam, Daniel B. Ennis, J. Paul Finn

Erschienen in: Pediatric Radiology | Ausgabe 9/2012

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Abstract

Background

Catheter rupture during CT angiography has prompted policies prohibiting the use of electronic injectors with peripherally inserted central venous catheters (PICCs) not only for CT but also for MRI. Consequently, many institutions mandate hand injection for MR angiography, limiting precision of infusion rates and durations of delivery.

Objective

To determine whether electronic injection of gadolinium-based contrast media through a range of small-caliber, single-lumen PICCs would be safe without risk of catheter rupture over the range of clinical protocols and determine whether programmed flow rates and volumes were realized when using PICCs for contrast delivery.

Materials and methods

Experiments were performed and recorded using the Medrad Spectris Solaris EP MR Injection System. PICC sizes, contrast media and flow rates were based on common institutional protocols.

Results

No catheters were damaged during any experiments. Mean difference between programmed and delivered volume was 0.07 ± 0.10 mL for all experiments. Reduced flow rates and prolonged injection durations were observed when the injector’s pressure-limiting algorithm was triggered, only in protocols outside the clinical range.

Conclusion

PICCs commonly used in children can withstand in vitro power injection of gadolinium-based contrast media at protocols significantly above clinical levels.
Literatur
1.
Zurück zum Zitat Bowen A, Carapetis J (2011) Advances in the diagnosis and management of central venous access device infections in children. Adv Exp Med Biol 697:91–106PubMedCrossRef Bowen A, Carapetis J (2011) Advances in the diagnosis and management of central venous access device infections in children. Adv Exp Med Biol 697:91–106PubMedCrossRef
2.
Zurück zum Zitat Vo JN, Hoffer FA, Shaw DW (2010) Techniques in vascular and interventional radiology: pediatric central venous access. Tech Vasc Interv Radiol 13:250–257PubMedCrossRef Vo JN, Hoffer FA, Shaw DW (2010) Techniques in vascular and interventional radiology: pediatric central venous access. Tech Vasc Interv Radiol 13:250–257PubMedCrossRef
3.
Zurück zum Zitat Chemaly RF, de Parres JB, Rehm SJ et al (2002) Venous thrombosis associated with peripherally inserted central catheters: a retrospective analysis of the Cleveland Clinic experience. Clin Infect Dis 34:1179–1183PubMedCrossRef Chemaly RF, de Parres JB, Rehm SJ et al (2002) Venous thrombosis associated with peripherally inserted central catheters: a retrospective analysis of the Cleveland Clinic experience. Clin Infect Dis 34:1179–1183PubMedCrossRef
4.
Zurück zum Zitat King DS, da Cruz E, Kaufman J (2010) A model for a nurse-led programme of bedside placement of peripherally inserted central catheters in neonates and infants with congenital cardiac disease. Cardiol Young 20:302–307PubMedCrossRef King DS, da Cruz E, Kaufman J (2010) A model for a nurse-led programme of bedside placement of peripherally inserted central catheters in neonates and infants with congenital cardiac disease. Cardiol Young 20:302–307PubMedCrossRef
5.
Zurück zum Zitat Donnelly LF, Emery KH, Brody AS et al (2001) Minimizing radiation dose for pediatric body applications of single-detector helical CT: strategies at a large Children’s Hospital. AJR 176:303–306PubMed Donnelly LF, Emery KH, Brody AS et al (2001) Minimizing radiation dose for pediatric body applications of single-detector helical CT: strategies at a large Children’s Hospital. AJR 176:303–306PubMed
6.
Zurück zum Zitat Brenner DJ, Elliston CD, Hall EJ et al (2001) Estimates of the cancer risks from pediatric CT radiation are not merely theoretical: comment on ‘point/counterpoint: in x-ray computed tomography, technique factors should be selected appropriate to patient size. against the proposition. Med Phys 28:2387–2388PubMedCrossRef Brenner DJ, Elliston CD, Hall EJ et al (2001) Estimates of the cancer risks from pediatric CT radiation are not merely theoretical: comment on ‘point/counterpoint: in x-ray computed tomography, technique factors should be selected appropriate to patient size. against the proposition. Med Phys 28:2387–2388PubMedCrossRef
7.
Zurück zum Zitat Brenner D, Elliston C, Hall E et al (2001) Estimated risks of radiation-induced fatal cancer from pediatric CT. AJR 176:289–296PubMed Brenner D, Elliston C, Hall E et al (2001) Estimated risks of radiation-induced fatal cancer from pediatric CT. AJR 176:289–296PubMed
8.
Zurück zum Zitat Jou LD, Rapp J, Saloner D (2004) Transport of contrast agents in contrast-enhanced magnetic resonance angiography. Magn Reson Imaging 22:495–504PubMedCrossRef Jou LD, Rapp J, Saloner D (2004) Transport of contrast agents in contrast-enhanced magnetic resonance angiography. Magn Reson Imaging 22:495–504PubMedCrossRef
9.
Zurück zum Zitat Morasch MD, Collins J, Pereles FS et al (2003) Lower extremity stepping-table magnetic resonance angiography with multilevel contrast timing and segmented contrast infusion. J Vasc Surg 37:62–71PubMedCrossRef Morasch MD, Collins J, Pereles FS et al (2003) Lower extremity stepping-table magnetic resonance angiography with multilevel contrast timing and segmented contrast infusion. J Vasc Surg 37:62–71PubMedCrossRef
10.
Zurück zum Zitat Salis AI, Eclavea A, Johnson MS et al (2004) Maximal flow rates possible during power injection through currently available PICCs: an in vitro study. J Vasc Interv Radiol 15:275–281PubMedCrossRef Salis AI, Eclavea A, Johnson MS et al (2004) Maximal flow rates possible during power injection through currently available PICCs: an in vitro study. J Vasc Interv Radiol 15:275–281PubMedCrossRef
11.
Zurück zum Zitat Coyle D, Bloomgarden D, Beres R et al (2004) Power injection of contrast media via peripherally inserted central catheters for CT. J Vasc Interv Radiol 15:809–814PubMedCrossRef Coyle D, Bloomgarden D, Beres R et al (2004) Power injection of contrast media via peripherally inserted central catheters for CT. J Vasc Interv Radiol 15:809–814PubMedCrossRef
12.
Zurück zum Zitat Kaste SC, Young CW (1996) Safe use of power injectors with central and peripheral venous access devices for pediatric CT. Pediatr Radiol 26:499–501PubMedCrossRef Kaste SC, Young CW (1996) Safe use of power injectors with central and peripheral venous access devices for pediatric CT. Pediatr Radiol 26:499–501PubMedCrossRef
13.
Zurück zum Zitat Herts BR, Cohen MA, McInroy B et al (1996) Power injection of intravenous contrast material through central venous catheters for CT: in vitro evaluation. Radiology 200:731–735PubMed Herts BR, Cohen MA, McInroy B et al (1996) Power injection of intravenous contrast material through central venous catheters for CT: in vitro evaluation. Radiology 200:731–735PubMed
14.
Zurück zum Zitat Ramasethu J (2008) Complications of vascular catheters in the neonatal intensive care unit. Clin Perinatol 35:199–222PubMedCrossRef Ramasethu J (2008) Complications of vascular catheters in the neonatal intensive care unit. Clin Perinatol 35:199–222PubMedCrossRef
15.
Zurück zum Zitat Sanelli PC, Deshmukh M, Ougorets I et al (2004) Safety and feasibility of using a central venous catheter for rapid contrast injection rates. AJR 183:1829–1834PubMed Sanelli PC, Deshmukh M, Ougorets I et al (2004) Safety and feasibility of using a central venous catheter for rapid contrast injection rates. AJR 183:1829–1834PubMed
16.
Zurück zum Zitat Rigsby CK, Gasber E, Seshadri R et al (2007) Safety and efficacy of pressure-limited power injection of iodinated contrast medium through central lines in children. AJR 188:726–732PubMedCrossRef Rigsby CK, Gasber E, Seshadri R et al (2007) Safety and efficacy of pressure-limited power injection of iodinated contrast medium through central lines in children. AJR 188:726–732PubMedCrossRef
17.
Zurück zum Zitat Macha DB, Nelson RC, Howle LE et al (2009) Central venous catheter integrity during mechanical power injection of iodinated contrast medium. Radiology 253:870–878PubMedCrossRef Macha DB, Nelson RC, Howle LE et al (2009) Central venous catheter integrity during mechanical power injection of iodinated contrast medium. Radiology 253:870–878PubMedCrossRef
Metadaten
Titel
Injection of gadolinium contrast through pediatric central venous catheters: a safety study
verfasst von
John M. Moriarty
Geoffrey L. Kung
Yanerys Ramos
Abbas N. Moghaddam
Daniel B. Ennis
J. Paul Finn
Publikationsdatum
01.09.2012
Verlag
Springer-Verlag
Erschienen in
Pediatric Radiology / Ausgabe 9/2012
Print ISSN: 0301-0449
Elektronische ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-012-2397-z

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