Interrelationship between iodine nutritional status of lactating mothers and their absolutely breast-fed infants in coastal districts of Gangetic West Bengal in India

Iodine nutritional status of 128 lactating mothers and their breast-fed infants (1–3 months) from iodine-replete villages during post-salt iodization period was evaluated. Mothers’ urine, blood, and breast milk (BM) and infants’ urine and blood were collected and analyzed for iodine and serum FT₄ and TSH estimation. Mothers’ and infants’ age, parity, occupation, education, and household income were recorded. Median urinary iodine concentration (UIC) of infants was 250 μg/L, indicating their iodine intake was more than adequate. Mothers’ median UIC was 185 μg/L, indicating adequate iodine nutrition; however, 13.28% had mild to severe deficiency. Median breast milk iodine concentration (BMIC) was 230 μg/L, which was more than their median UIC 185 μg/L. In iodine-deficient mothers, positive correlation was found between mothers’ and infants’ serum FT₄ and TSH levels, and negative correlation was found between mothers’ and infants’ serum FT₄ and TSH levels in excessive iodine nutrition group.

Conclusion: Iodine intake of breast-fed infants was at the limit of above requirement, and they are possibly at the risk of excess iodine intake. In iodine deficient and excessive iodine intake mothers, their infants’ serum FT₄ and TSH are independent on their iodine nutritional status but dependent on thyroid hormone profile of their mothers but differently.