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European Archives of Psychiatry and Clinical Neuroscience

Erschienen in:

01.08.2008 | ORIGINAL PAPER

Investigation of serum high-sensitive C-reactive protein levels across all mood states in bipolar disorder

verfasst von: Ângelo B. Cunha, Ana C. Andreazza, Fabiano A. Gomes, Benicio N. Frey, Leonardo E. da Silveira, Carlos A. Gonçalves, Flávio Kapczinski

Erschienen in: European Archives of Psychiatry and Clinical Neuroscience | Ausgabe 5/2008

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Abstract

There has been an increasing interest in the role of the immune and inflammatory systems in mood disorders. Mood episodes are associated with changes in acute phase proteins such as high-sensitivity C-reactive protein (hsCRP). The present study investigated serum hsCRP in manic, depressed, and euthymic BD patients as compared to matched healthy controls. Serum hsCRP was assessed using an ultrasensitive assay of particle-enhanced immunoturbidimetric latex agglutination. Serum hsCRP levels were increased in manic BD patients, as compared to euthymic, depressed patients and healthy controls (P < 0.001). These findings add to the notion that changes in the inflammatory system take place during acute episodes of mania.

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Titel: Investigation of serum high-sensitive C-reactive protein levels across all mood states in bipolar disorder
verfasst von: Ângelo B. Cunha
Ana C. Andreazza
Fabiano A. Gomes
Benicio N. Frey
Leonardo E. da Silveira
Carlos A. Gonçalves
Flávio Kapczinski
Publikationsdatum: 01.08.2008
Verlag: D. Steinkopff-Verlag
Erschienen in: European Archives of Psychiatry and Clinical Neuroscience / Ausgabe 5/2008
Print ISSN: 0940-1334
Elektronische ISSN: 1433-8491
DOI: https://doi.org/10.1007/s00406-007-0797-0

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