Ausgabe 2/2024
Inhalt (8 Artikel)
Safety and efficacy of apatinib in combination with chemotherapy with or without immunotherapy versus chemotherapy alone as first-line treatment for advanced gastric cancer
- Open Access
- Research
Lele Chang, Xuemei Zhang, Qian Ma, Lingyang Kong, Yang Yu, Ji Tao, Qingwei Li
PD-1 inhibitor combined with albumin paclitaxel and apatinib as second-line treatment for patients with metastatic gastric cancer: a single-center, single-arm, phase II study
- Open Access
- Research
Miaomiao Gou, Yong Zhang, Zhikuan Wang, Niansong Qian, Guanghai Dai
A phase 1b open-label study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of py314 in combination with pembrolizumab in patients with advanced renal cell carcinoma
- Research
Kathryn E. Beckermann, Amita Patnaik, Ira Winer, Winston Tan, Babar Bashir, Christos E. Kyriakopoulos, Randy F. Sweis, Marc Chamberlain, Brian I. Rini
Targeting LEF1-mediated epithelial-mesenchymal transition reverses lenvatinib resistance in hepatocellular carcinoma
- Research
Xinxiu Li, Hongmeng Su, Wenqing Tang, Shihui Shu, Luyu Zhao, Jinghan Sun, Hong Fan
First-line treatment of driver gene-negative metastatic lung adenocarcinoma with malignant pleural effusion: Should chemotherapy be combined with an immune checkpoint inhibitor or bevacizumab?
- Open Access
- Research
Yuanyuan Zhao, Ting Mei, Feifei Na, Xiaoman Tian, Rui Ao, Xiangyu Long, Qiang Luo, Ping Duan, Jiang Zhu, Yongsheng Wang, Meijuan Huang, Yongmei Liu, Youling Gong
The novel cytotoxic polybisphosphonate osteodex decreases bone resorption by enhancing cell death of mature osteoclasts without affecting osteoclastogenesis of RANKL-stimulated mouse bone marrow macrophages
- Open Access
- Research
Petra Henning, Anna Westerlund, Sofia Movérare-Skrtic, Catharina Lindholm, Marcela Márquez-Méndez, Sten Nilsson, Anders R. Holmberg, Ulf H. Lerner
A multicenter phase Ia study of AbGn-107, a novel antibody–drug conjugate, in patients with advanced gastrointestinal cancer
- Research
Andrew H. Ko, Andrew L. Coveler, Benjamin L. Schlechter, Tanios Bekaii-Saab, Brian M. Wolpin, Jeffrey W. Clark, Bruno Bockorny, Li-Yuan Bai, Yu-Chin Lin, Evelyn Chiang, Peter Langecker, Shih-Yao Lin
Impact of carbamazepine on SMARCA4 (BRG1) expression in colorectal cancer: modulation by KRAS mutation status
- Open Access
- Research
Aaron Shaykevich, Danbee Chae, Isaac Silverman, Jeremy Bassali, Netanel Louloueian, Alexander Siegman, Gargi Bandyopadhyaya, Sanjay Goel, Radhashree Maitra
