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Investigational New Drugs

Ausgabe 4/2003

Inhalt (12 Artikel)

In vivo antitumor activity of a novel sulfonamide, HMN-214, against human tumor xenografts in mice and the spectrum of cytotoxicity of its active metabolite, HMN-176

Manabu Takagi, Takuya Honmura, Shuuji Watanabe, Reiko Yamaguchi, Masaki Nogawa, Ikumi Nishimura, Fumitaka Katoh, Masato Matsuda, Hiroyoshi Hidaka

Quinolizidinyl derivatives of iminodibenzyl and phenothiazine as multidrug resistance modulators in ovarian cancer cells

Federica Barbieri, Angela Alama, Bruno Tasso, Vito Boido, Cristina Bruzzo, Fabio Sparatore

A study of a different dose-intense infusion schedule of phenylacetate in patients with recurrent primary brain tumors

Susan M. Chang, John G. Kuhn, H. Ian Robins, S. Clifford Schold, Alexander M. Spence, Mitchel S. Berger, Minesh P. Mehta, Ian Pollack, Mark Gilbert, Michael D. Prados

Weekly regimen of irinotecan/docetaxel in previously treated non-small cell lung cancer patients and correlation with uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) polymorphism

Albert Font, José Miguel Sánchez, Miquel Tarón, Eva Martinez-Balibrea, José Javier Sánchez, José Luis Manzano, Mireia Margelí, Martin Richardet, Agustí Barnadas, Albert Abad, Rafael Rosell

Pharmacokinetics and safety of ILX23-7553, a non-calcemic-vitamin D3 analogue, in a phase I study of patients with advanced malignancies

Robert Wieder, Steven C. Novick, Bruce W. Hollis, Margarette Bryan, Suzanne M. Chanel, Kate Owusu, Danielle Camastra, Tracie Saunders, Lillian Pliner, Jonathan Harrison, Peter Bonate, Tom Williams, Steven Soignet

Activity of weekly irinotecan (CPT-11) in patients with advanced non-small cell lung cancer pretreated with platinum and taxanes

Rosa Sánchez, Emilio Esteban, Isabel Palacio, Yolanda Fernández, Isabel Muñiz, Jose M. Vieitez, Joaquin Fra, Pilar Blay, Noemí Villanueva, Esther Uña, Beatriz Mareque, Enrique Estrada, Jose M. Buesa, Angel J. Lacave

A phase II study of rebeccamycin analog (NSC-655649) in metastatic renal cell cancer

Maha Hussain, Ulka Vaishampayan, Lance K. Heilbrun, Vikash Jain, Patricia M. LoRusso, Percy Ivy, Lawrence Flaherty

A phase II study of topotecan in patients with anaplastic oligodendroglioma or anaplastic mixed oligoastrocytoma

Karl Bélanger, David MacDonald, Gregory Cairncross, Stan Gertler, Peter Forsyth, Susan Burdette-Radoux, Julie Bergeron, Denis Soulières, Samuel Ludwin, Nancy Wainman, Elizabeth Eisenhauer

An open label, non-comparative phase II study of topotecan as salvage treatment for patients with soft tissue sarcoma

Peter Reichardt, Karin Oechsle, Daniel Pink, Carsten Bokemeyer, F. Schneller, Rolf Issels, Lothar Kanz, Jörg Thomas Hartmann

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