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European Archives of Psychiatry and Clinical Neuroscience

Erschienen in:

01.10.2007 | ORIGINAL PAPER

Is depression a risk factor for heart complaints?

Longitudinal aspects in the Zurich study

verfasst von: Dominique Eich, MD, Christoph Neuhaus, MSc, Alex Gamma, PhD, Jules Angst, MD, Wulf Rössler, MD, MSc, Vladeta Ajdacic-Gross, PhD, Milos Opravil

Erschienen in: European Archives of Psychiatry and Clinical Neuroscience | Ausgabe 7/2007

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Abstract

Background

The objective of this longitudinal study was to assess the association between major depression and heart complaints in a population of young and healthy adults.

Methods

Starting at the age 20/21, participants of the Zurich Study underwent 6 structured, psychological interviews during a span of 20 years. We evaluated longitudinal data from 277 persons who participated in all 6 interviews including questions about heart complaints.

Results

Over 20 years, heart complaints were reported by two thirds of participants, and the frequency of depression was 11.4%. At the age of 40/41, heart complaints were significantly associated with earlier heart complaints and major depression, both more often in women. Recurrent brief depression showed a tendency, but neither minor depression nor depressive symptoms were predictive for later heart complaints.

Conclusions

This study suggests that major depression is a predictor for heart complaints at the age of 40 and that the severity of depressive disorder in younger age has an effect on subsequent heart complaints. Follow-up data will help to elucidate whether these subjective heart complaints show any correlation with a later coronary heart disease.

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Titel: Is depression a risk factor for heart complaints?
Longitudinal aspects in the Zurich study
verfasst von: Dominique Eich, MD
Christoph Neuhaus, MSc
Alex Gamma, PhD
Jules Angst, MD
Wulf Rössler, MD, MSc
Vladeta Ajdacic-Gross, PhD
Milos Opravil
Publikationsdatum: 01.10.2007
Verlag: Springer-Verlag
Erschienen in: European Archives of Psychiatry and Clinical Neuroscience / Ausgabe 7/2007
Print ISSN: 0940-1334
Elektronische ISSN: 1433-8491
DOI: https://doi.org/10.1007/s00406-007-0747-x

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Abstract

Background

Methods

Results

Conclusions

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