Osseous metastatic involvement of the spinal column affects many patients with a primary tumour disease of all entities. In many cases this involvement is indicative of a progressed stage of a primary malignant disease. 70 percent of all patients who die of the sequelae of the tumour disease exhibit bone metastases [
1]. 80 percent of all osseous metastases originate from mammary, prostatic, bronchial, renal-cell, or thyroid carcinomas [
2]. In men, the primary tumour in 60 percent of all cases is a carcinoma of the prostate [
3], among women, it is in 70 percent of the cases a mammary carcinoma. 30 percent of all metastases of the skeletal system and ten percent of all primary bone tumours are found in the spinal column. The former are located in the lumbar (52%), thoracic (36%) and cervical column (12%) [
4]. The consequences are pain both at rest and under exertion, impairments in going about day-to-day activities, diminished performance, the risk of pathological fractures, and neurological deficits. Pain is the essential factor for the decrease in the quality of life of patients with bone metastases [
5]. Pathological fractures occur in 5% and compressions of the spinal cord in 10-15% of all patients [
6]. In its role as the central axial organ, the spinal column stands in the focus of all mobility options of the individual patient and, when compromised, constitutes a mobility-restricting factor. The generation of power by the paravertebral muscles and the patient's mobility correspondingly play a decisive role regarding his/her quality of life. In their study involving patients with an advanced tumour disorder, Cheville et al. [
7] were able to demonstrate that physiotherapy can be performed parallel to radiotherapy with a beneficial effect. The primary intention of this study is to review the feasibility of the project. Strengthening the paravertebral muscular system is reported to have a positive effect not only on the sensation of pain, but also on the quality of life and fatigue. Isometric training of the paravertebral muscles is anticipated to produce a raised perfusion of the segments of the vertebral column involved. This aspect may, in combination with percutaneous radiotherapy, result in a better response to therapy. The potentially raised risk of fracture in combination with an injury of the spinal cord involving neurological deficits results in patients suffering a constant state of anxiety of varying distinction. In most cases, this fear of such a serious event in turn results in an unintended "vicious circle" comprising immobility, pain, and ever-decreasing physical performance. Pain, anxiety, and impaired physical mobility are in virtually all cases associated with a reduced quality of life and frequently result in negative consequences for the patients' participation in society. This controlled combination therapy may relieve the negative effects of the tumour disease for the patients. The literature has so far not described any dedicated ergotherapeutical measures employing isometric muscle training in connection with bone metastases. The extent to which specific, regular, and differentiated training of the paravertebral muscle system can be performed may be jeopardized by the reduced general condition of the patients, their pain situation, and their fear of suffering fractures, which is why the feasibility of the study poses the greatest challenge. In terms of the localization and pain symptoms, these are similar to the complaints experienced in osteoporosis and vertebral-disk syndromes. Among these patients there are numerous indications of the positive effect of targeted physical exercise on pain and mobility [
8‐
11]. The findings of this direction of research shall also be considered in this study. Patients undergoing treatment in the form of percutaneous radiotherapy who from the orthopedic and radiological aspects are classified as not being at risk of suffering fractures will receive a second component of therapy involving isometric training of the paravertebral muscle system.