International Journal of Legal Medicine OnlineFirst articles

28.03.2024 | Original Article

Dental age assessment and dental scoring systems: combined different statistical methods

Age Estimation has been considered as a human basic right since 1837 when Edwin Saunders defends, for the first time, tables for dental age assessment based on the chronology of tooth eruption [ 1 ]. Nowadays, the rights of a child, as defined by …

verfasst von:: Cristiana Palmela Pereira, Ana Rodrigues, Diana Augusto, Adriana Santos, Valon Nushic, Rui Santos

27.03.2024 | Original Article

Development of a screening system of gene sets for estimating the time of early skeletal muscle injury based on second-generation sequencing technology

The present study is aimed to address the challenge of wound age estimation in forensic science by identifying reliable genetic markers using low-cost and high-precision second-generation sequencing technology. A total of 54 Sprague-Dawley rats …

verfasst von:: Junyi Shen, Hao Sun, Shidong Zhou, Liangliang Wang, Chaoxiu Dong, Kang Ren, Qiuxiang Du, Jie Cao, Yingyuan Wang, Junhong Sun

26.03.2024 | Original Article

Prioritizing a high posterior probability threshold leading to low error rate over high classification accuracy: the validity of MorphoPASSE software for cranial morphological sex estimation in a contemporary population

An increasing number of software tools can be used in forensic anthropology to estimate a biological profile, but further studies in other populations are required for more robust validation. The present study aimed to evaluate the validity of …

verfasst von:: Anežka Pilmann Kotěrová, Frédéric Santos, Šárka Bejdová, Rebeka Rmoutilová, MennattAllah Hassan Attia, Ahmed Habiba, Jana Velemínská, Jaroslav Brůžek

23.03.2024 | Original Article

Immunohistochemical analysis of PDGFR-α for wound age determination

Immunohistochemical analysis of platelet-derived growth factor receptor-α (PDGFR-α) was performed on human skin wounds obtained from forensic autopsy cases. Thirty human skin wounds were collected at different post-infliction intervals as follows: …

verfasst von:: Wei Zhang, Yuko Ishida, Mizuho Nosaka, Yumi Kuninaka, Akiko Ishigami, Haruki Yasuda, Ayumi Kofuna, Ten Kamata, Utako Goto, Toshikazu Kondo

Open Access 23.03.2024 | Original Article

New alginate-gelatine method for casting of staining inside firearm barrels

Contact shots to the head often leave behind biological traces inside firearm barrels, a phenomenon of great forensic interest. Until now, the visualization and preservation of these traces presented a significant challenge, lacking a reliable …

verfasst von:: Christian Schyma, Matthias Berthold

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20.03.2024 | Letter to the Editor

Commentary on Stigter H, Krap T, Gelderman T, Dijkhuizen L, Duijst WLJM. Technical note: practical application of post-mortem mechanical stimulation of skeletal muscle, a field study

verfasst von:: Burkhard Madea, Elke Doberentz

Open Access 20.03.2024 | Original Article

Evaluation of the usefulness of insertion-null markers in critical skeletal remains

Forensic DNA analysis in compromised skeletal remains may pose challenges due to DNA degradation, often resulting in partial or negative autosomal STRs profiles. To address this issue, alternative approaches such as mitochondrial DNA or SNPs …

verfasst von:: Christian Haarkötter, María Saiz, Xiomara Gálvez, Diana C. Vinueza-Espinosa, María Isabel Medina-Lozano, Juan Carlos Álvarez, Jose Antonio Lorente

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16.03.2024 | Original Article

From degraded to deciphered: ATAC-seq’s application potential in forensic diagnosis

In recent years, molecular biology-based diagnostic techniques have made remarkable strides and are now extensively utilized in clinical practice, providing invaluable insights for disease diagnosis and treatment. However, forensic medicine …

verfasst von:: Manrui Li, Yuntian Jin, Yang Xu, Yihan Sun, Ruixuan Yuan, Xiao Zhang, Shengqiu Qu, Meili Lv, Miao Liao, Weibo Liang, Lin Zhang, Xiameng Chen

12.03.2024 | Review

Advances in body fluid identification: MiRNA markers as powerful tool

Body fluids are one of the most encountered types of evidence in any crime and are commonly used for identifying a person’s identity. In addition to these, they are also useful in ascertaining the nature of crime by determining the ty pe of fluid …

verfasst von:: Mohd Hamza, Deeksha Sankhyan, Saurabh Shukla, Preeti Pandey

Open Access 12.03.2024 | Original Article

Automatic and robust estimation of sex and chronological age from panoramic radiographs using a multi-task deep learning network: a study on a South Korean population

Sex and chronological age estimation are crucial in forensic investigations and research on individual identification. Although manual methods for sex and age estimation have been proposed, these processes are labor-intensive, time-consuming, and …

verfasst von:: Se-Jin Park, Su Yang, Jun-Min Kim, Ju-Hee Kang, Jo-Eun Kim, Kyung-Hoe Huh, Sam-Sun Lee, Won-Jin Yi, Min-Suk Heo

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Open Access 08.03.2024 | Original Article

Catch me if you can—emission patterns of human bodies in relation to postmortem changes

The present study examines for the first time the emission patterns and olfactory signatures of 9 complete human corpses of different stages of decomposition. Air sampling was performed inside the body bags with solid sorbents and analysed by …

verfasst von:: Alexandra Schieweck, Nicole Schulz, Jens Amendt, Christoph Birngruber, Franziska Holz

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05.03.2024 | Case Report

Identification of a murder caused by brodifacoum poisoning based on clinical examinations and LC-MS/MS results

Brodifacoum exerts its antagonistic effect against the metabolism of vitamin K, an essential component in the synthesis of blood coagulation factors. This effect ultimately hinders the blood’s capacity to clot effectively, rendering it a commonly …

verfasst von:: Zhonghao Yu, Erjuan Zhao, Qing Shi, Yuhao Yuan, Jinghong Ma, Luwang Zhou, Yijie Duan, Yiwu Zhou

04.03.2024 | Original Article

Evaluation of metal ions and DNA recovery from the surface of fired and unfired brass ammunition to improve STR profiling

Interest in recovering DNA from the surface of ammunition evidence for genotyping has increased over the past few years. Numerous studies have examined a variety of methods to maximize DNA recovery from these types of challenging samples, but …

verfasst von:: Natalia Czado, Rachel Houston, Sheree Hughes

01.03.2024 | Review

Understanding methiopropamine, a new psychoactive substance: an in-depth review on its chemistry, pharmacology and implications to human health

Methiopropamine or 1-(thiophen-2-yl)-2-methylaminopropane (MPA) is a thiophene ring-based structural analogue of methamphetamine, first synthesized in 1942 but become popular when it started to be available for purchase on websites selling ‘legal …

verfasst von:: Mohd Khairulanwar Bunaim, Hanafi Ahmad Damanhuri, Hui-Yin Yow, Nor Syafinaz Yaakob, Mohd Makmor-Bakry, Norazrina Azmi

28.02.2024 | Original Article

Developmental validation of the STRSeqTyper122 kit for massively parallel sequencing of forensic STRs

Massively parallel sequencing allows for integrated genotyping of different types of forensic markers, which reduces DNA consumption, simplifies experimental processes, and provides additional sequence-based genetic information. The STRseqTyper122 …

verfasst von:: Li-Liang Guo, Jia-Hui Yuan, Chi Zhang, Jie Zhao, Yi-Ren Yao, Ke-Li Guo, Yang Meng, An-Quan Ji, Ke-Lai Kang, Le Wang

27.02.2024 | Original Article

Quantitative evaluation of endometrium-expressed mRNAs for the purpose of discriminating between menstruation and traumatic vaginal injury in sexual assault cases

In sexual assault cases, it is crucial to discriminate between peripheral blood and menstrual blood to provide evidence for vaginal intercourse with traumatic injury. In this study, the menstrual blood mRNA markers progestagen-associated …

verfasst von:: Tomoko Akutsu, Saki Minegishi, Ken Watanabe, Kochi Toyomane, Takayuki Yamagishi, Koichi Sakurada

24.02.2024 | Original Article

Hair toxicological analysis of infants and their mothers: a 5-year retrospective study focusing on cocaine

Prenatal and infant exposure to drugs of abuse is an emerging social and public health problem affecting children health and which may relate to child abuse and neglect. Exposure to drugs of abuse may occur through different routes, including …

verfasst von:: Clara Cestonaro, Claudio Terranova, Massimo Carollo, Alessia Russo, Melissa Rosa-Rizzotto, Guido Viel, Donata Favretto, Anna Aprile

24.02.2024 | Review

Efficacy of the methods of age determination using artificial intelligence in panoramic radiographs — a systematic review

The aim of this systematic review is to analyze the literature to determine whether the methods of artificial intelligence are effective in determining age in panoramic radiographs. Searches without language and year limits were conducted in …

verfasst von:: Tania Camila Niño-Sandoval, Ana Milena Doria-Martinez, Ruby Amparo Vásquez Escobar, Elizabeth Llano Sánchez, Isabella Bermón Rojas, Laura Cristina Vargas Álvarez, David Stephen Fernandez Mc Cann, Liliana Marcela Támara-Patiño

24.02.2024 | Original Article

The influence of biological relatedness on sexual dimorphism and sex classification based on external morphology of the frontal bone

The most significant sexual differences in the human skull are located in the upper third of the face (the frontal bone), which is a useful research object, mainly in combination with virtual anthropology methods. However, the influence of …

verfasst von:: Markéta Hamanová Čechová, Jan Cvrček, Ján Dupej, Jaroslav Brůžek, Jana Velemínská

Open Access 22.02.2024 | Case Report

Subject-specific finite element head models for skull fracture evaluation—a new tool in forensic pathology

Post-mortem computed tomography (PMCT) enables the creation of subject-specific 3D head models suitable for quantitative analysis such as finite element analysis (FEA). FEA of proposed traumatic events is an objective and repeatable numerical …

verfasst von:: Mikkel Jon Henningsen, Natalia Lindgren, Svein Kleiven, Xiaogai Li, Christina Jacobsen, Chiara Villa

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Die Highlights vom Kongress des American College of Cardiology 2024

Springer Medizin