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Erschienen in: HNO Nachrichten 1/2019

06.02.2019 | Aphthen | Zertifizierte Fortbildung

Von harmlosen Aphthen bis zu fortgeschrittenen Leukoplakien

Krankheiten der oralen Mukosa

verfasst von: Prof. Dr. med. Thomas Dirschka

Erschienen in: HNO Nachrichten | Ausgabe 1/2019

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Zusammenfassung

Erkrankungen der Mundschleimhaut sind häufig gutartig und selbstlimitierend. Dieser Umstand kann jedoch dazu führen, dass infektiöse Ulzerationen oder gar Karzinome als harmlos fehlinterpretiert werden. Eine genaue Kenntnis der Differenzialdiagnosen und eine sorgfältige Untersuchung des Patienten sind daher unerlässlich.
Literatur
1.
Zurück zum Zitat Khudhur et al. Oral lichenoid tissue reactions: diagnosis and classification. Exp Rev Mol Diag 2014; 14: 169–84CrossRef Khudhur et al. Oral lichenoid tissue reactions: diagnosis and classification. Exp Rev Mol Diag 2014; 14: 169–84CrossRef
2.
Zurück zum Zitat Lavanya N et al. Oral lichen planus: An update on pathogenesis and treatment. J Oral Maxillofac Pathol 2011; 15: 127–32CrossRef Lavanya N et al. Oral lichen planus: An update on pathogenesis and treatment. J Oral Maxillofac Pathol 2011; 15: 127–32CrossRef
3.
Zurück zum Zitat Gorouhi F et al. Cutaneous and mucosal lichen planus: A comprehensive review of clinical subtypes, risk factors, diagnosis, and prognosis. ScientificWorldJournal 2014; 742826 Gorouhi F et al. Cutaneous and mucosal lichen planus: A comprehensive review of clinical subtypes, risk factors, diagnosis, and prognosis. ScientificWorldJournal 2014; 742826
4.
Zurück zum Zitat Eisen D. The clinical manifestations and treatment of oral lichen planus. Dermatol Clin 2003; 21: 79–89CrossRef Eisen D. The clinical manifestations and treatment of oral lichen planus. Dermatol Clin 2003; 21: 79–89CrossRef
5.
Zurück zum Zitat Rapp U et al. Investigation of contact allergy to dental metals in 206 patients. Contact Dermatitis 2009; 60: 339–43CrossRef Rapp U et al. Investigation of contact allergy to dental metals in 206 patients. Contact Dermatitis 2009; 60: 339–43CrossRef
6.
Zurück zum Zitat Yiannias JA et al. Relevant contact sensitivities in patients with the diagnosis of oral lichen planus. J Am Acad Dermatol 2000; 42: 177–82CrossRef Yiannias JA et al. Relevant contact sensitivities in patients with the diagnosis of oral lichen planus. J Am Acad Dermatol 2000; 42: 177–82CrossRef
7.
Zurück zum Zitat Feller L et al. Review: allergic contact stomatitis. Oral Surg Oral Med Oral Pathol Oral Radiol 2017; 123: 559–65CrossRef Feller L et al. Review: allergic contact stomatitis. Oral Surg Oral Med Oral Pathol Oral Radiol 2017; 123: 559–65CrossRef
8.
Zurück zum Zitat Suresh SS et al. Medical management of oral lichen planus: A systematic review. J Clin Diagn Res 2016; 10: 10–5 Suresh SS et al. Medical management of oral lichen planus: A systematic review. J Clin Diagn Res 2016; 10: 10–5
9.
Zurück zum Zitat Sonthalia S et al. Comparative efficacy of tacrolimus 0,1 % ointment and clobetasol 0,05 % ointment in oral lichen planus: a randomized double-blind trial. Int J Dermatol 2012; 51: 1371–8CrossRef Sonthalia S et al. Comparative efficacy of tacrolimus 0,1 % ointment and clobetasol 0,05 % ointment in oral lichen planus: a randomized double-blind trial. Int J Dermatol 2012; 51: 1371–8CrossRef
10.
Zurück zum Zitat Yoke PC et al. A randomized controlled trial to compare steroid with cyclosporine for the topical treatment of lichen planus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006; 102: 47–55CrossRef Yoke PC et al. A randomized controlled trial to compare steroid with cyclosporine for the topical treatment of lichen planus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006; 102: 47–55CrossRef
11.
Zurück zum Zitat Olson KA et al. Toxic tacrolimus levels after application of topical tacrolimus and use of occlusive dressings in two bone marrow transplant recipients with cutaneous graft-versus-host disease. Pharmacotherapy 2014; 34: 60–4CrossRef Olson KA et al. Toxic tacrolimus levels after application of topical tacrolimus and use of occlusive dressings in two bone marrow transplant recipients with cutaneous graft-versus-host disease. Pharmacotherapy 2014; 34: 60–4CrossRef
12.
Zurück zum Zitat Goodson ML et al. Efficacy of oral brush biopsy in potentially malignant disorder management. J Oral Pathol Med 2017; 46: 896–901PubMed Goodson ML et al. Efficacy of oral brush biopsy in potentially malignant disorder management. J Oral Pathol Med 2017; 46: 896–901PubMed
13.
Zurück zum Zitat Cai W et al. Current approaches to the diagnosis and treatment of white sponge nevus. Expert Rev Mol Med 2015; 17: e9CrossRef Cai W et al. Current approaches to the diagnosis and treatment of white sponge nevus. Expert Rev Mol Med 2015; 17: e9CrossRef
14.
Zurück zum Zitat Zeidan MJ et al. Behçet’s disease physiopathology: A contemporary review. Auto Immun Highlights. 2016; 7: 4CrossRef Zeidan MJ et al. Behçet’s disease physiopathology: A contemporary review. Auto Immun Highlights. 2016; 7: 4CrossRef
15.
Zurück zum Zitat International Team for the Revision of the International Criteria for Behçet’s Disease (ITRICBD). The International Criteria for Behçet’s Disease (ICBD): a collaborative study of 27 countries on the sensitivity and specificity of the new criteria. J Eur Acad Dermatol Venereol 2014; 28: 338–47 International Team for the Revision of the International Criteria for Behçet’s Disease (ITRICBD). The International Criteria for Behçet’s Disease (ICBD): a collaborative study of 27 countries on the sensitivity and specificity of the new criteria. J Eur Acad Dermatol Venereol 2014; 28: 338–47
16.
Zurück zum Zitat Alpsoy E. Behçet’s disease: A comprehensive review with a focus on epidemiology, etiology and clinical features, and management of mucocutaneous lesions. J Dermatol 2016; 43: 620–32CrossRef Alpsoy E. Behçet’s disease: A comprehensive review with a focus on epidemiology, etiology and clinical features, and management of mucocutaneous lesions. J Dermatol 2016; 43: 620–32CrossRef
17.
Zurück zum Zitat Hatemi G et al. Apremilast for Behçet’s syndrome — a phase 2, placebo-controlled study. N Engl J Med 2015; 372: 1510–8CrossRef Hatemi G et al. Apremilast for Behçet’s syndrome — a phase 2, placebo-controlled study. N Engl J Med 2015; 372: 1510–8CrossRef
18.
Zurück zum Zitat Liang MW et al. Oral Aphthosis. Management gaps and recent advances. Ann Acad Med Singapore 2012; 41: 463–70PubMed Liang MW et al. Oral Aphthosis. Management gaps and recent advances. Ann Acad Med Singapore 2012; 41: 463–70PubMed
19.
Zurück zum Zitat S2k-Leitlinie (Langversion): Diagnostik und Therapieoptionen von Aphthen und aphthoiden Läsionen der Mund- und Rachenschleimhaut. AWMF-Registernummer: 007-101, Stand: November 2016 S2k-Leitlinie (Langversion): Diagnostik und Therapieoptionen von Aphthen und aphthoiden Läsionen der Mund- und Rachenschleimhaut. AWMF-Registernummer: 007-101, Stand: November 2016
20.
21.
Zurück zum Zitat Horváth ON et al. Entzündliche orale Schleimhautkrankheiten. Hautarzt 2016; 67: 786–92CrossRef Horváth ON et al. Entzündliche orale Schleimhautkrankheiten. Hautarzt 2016; 67: 786–92CrossRef
22.
Zurück zum Zitat Benoit S et al. Differenzialdiagnose erosiver und ulzeröser Mundschleimhautkrankheiten im Kindesalter. Hautarzt 2015; 66: 258–66CrossRef Benoit S et al. Differenzialdiagnose erosiver und ulzeröser Mundschleimhautkrankheiten im Kindesalter. Hautarzt 2015; 66: 258–66CrossRef
23.
Zurück zum Zitat Akintoye SO et al. Recurrent aphthous stomatitis. Dent Clin North Am. 2014; 58: 281–97CrossRef Akintoye SO et al. Recurrent aphthous stomatitis. Dent Clin North Am. 2014; 58: 281–97CrossRef
24.
Zurück zum Zitat Dhanrajani P et al. Oral eosinophilic or traumatic ulcer: A case report and brief review. Natl J Maxillofac Surg 2015; 6: 237–40CrossRef Dhanrajani P et al. Oral eosinophilic or traumatic ulcer: A case report and brief review. Natl J Maxillofac Surg 2015; 6: 237–40CrossRef
25.
Zurück zum Zitat Lengfeld J et al. Biphosphonate-mediated oral ulcers: A rare diagnosis of erosive oral lesions. Dermatology 2016; 232: 117–21CrossRef Lengfeld J et al. Biphosphonate-mediated oral ulcers: A rare diagnosis of erosive oral lesions. Dermatology 2016; 232: 117–21CrossRef
26.
Zurück zum Zitat Lambertini M et al. Oral melanoma and other pigmentations: when to biopsy? J Eur Acad Dermato Venereol 2017; http://doi.org/10.111/jdv.14574 Lambertini M et al. Oral melanoma and other pigmentations: when to biopsy? J Eur Acad Dermato Venereol 2017; http://​doi.​org/​10.​111/​jdv.​14574
27.
Zurück zum Zitat Al-Ansari S et al. Oral mucositis induced by anticancer therapies. Curr Oral Health Rep 2014; 2: 202–11CrossRef Al-Ansari S et al. Oral mucositis induced by anticancer therapies. Curr Oral Health Rep 2014; 2: 202–11CrossRef
28.
Zurück zum Zitat Buglione M et al. Oral toxicity management in head and neck cancer patients treated with chemotherapy and radiation: Xerostomia and trismus (Part 2). Literature review and consensus statement. Crit Rev Oncol Hematol 2016; 102: 47–54CrossRef Buglione M et al. Oral toxicity management in head and neck cancer patients treated with chemotherapy and radiation: Xerostomia and trismus (Part 2). Literature review and consensus statement. Crit Rev Oncol Hematol 2016; 102: 47–54CrossRef
29.
Zurück zum Zitat Edens MH et al. Intraoral pain disorders. Oral Maxillofac Surg Clin North Am 2016; 28: 275–88CrossRef Edens MH et al. Intraoral pain disorders. Oral Maxillofac Surg Clin North Am 2016; 28: 275–88CrossRef
30.
31.
Zurück zum Zitat De Sanctis V et al. Mucositis in head and neck cancer patients treated with radiotherapy and systemic therapies: Literature review and consensus statements. Crit Rev Oncol Hematol 2016; 100: 147–66CrossRef De Sanctis V et al. Mucositis in head and neck cancer patients treated with radiotherapy and systemic therapies: Literature review and consensus statements. Crit Rev Oncol Hematol 2016; 100: 147–66CrossRef
32.
33.
Zurück zum Zitat Manzi Nde M et al. Prophylaxis for mucositis induced by ambulatory chemotherapy: Systematic review. J Adv Nurs 2016; 72: 735–46CrossRef Manzi Nde M et al. Prophylaxis for mucositis induced by ambulatory chemotherapy: Systematic review. J Adv Nurs 2016; 72: 735–46CrossRef
34.
Zurück zum Zitat Tanasiewicz M et al. Xerostomia of various etiologies: A review of the literature. Adv Clin Exp Med 2016; 25: 199–206CrossRef Tanasiewicz M et al. Xerostomia of various etiologies: A review of the literature. Adv Clin Exp Med 2016; 25: 199–206CrossRef
35.
Zurück zum Zitat Cuba LF et al. Cannabidiol: an alternative therapeutic agent for oral mucositis? J Clin Pharm Ther 2017; 42: 245–50CrossRef Cuba LF et al. Cannabidiol: an alternative therapeutic agent for oral mucositis? J Clin Pharm Ther 2017; 42: 245–50CrossRef
Metadaten
Titel
Von harmlosen Aphthen bis zu fortgeschrittenen Leukoplakien
Krankheiten der oralen Mukosa
verfasst von
Prof. Dr. med. Thomas Dirschka
Publikationsdatum
06.02.2019
Verlag
Springer Medizin
Erschienen in
HNO Nachrichten / Ausgabe 1/2019
Print ISSN: 0177-1000
Elektronische ISSN: 2198-6533
DOI
https://doi.org/10.1007/s00060-019-5803-4

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