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International Urogynecology Journal

Erschienen in:

03.03.2020 | Original Article

Lightweight transvaginal mesh is associated with lower mesh exposure rates than heavyweight mesh

verfasst von: Nicola Dykes, Debjyoti Karmakar, Lynsey Hayward

Erschienen in: International Urogynecology Journal | Ausgabe 9/2020

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Abstract

Introduction and hypothesis

There has been a scarcity of long-term published data comparing lightweight versus heavier weight transvaginal mesh for prolapse repair. The aim was to ascertain the long-term rates of recurrent prolapse and mesh exposure in a cohort of vaginal repairs utilizing two different weights of transvaginal mesh.

Methods

Data were prospectively collected on all mesh-augmented vaginal prolapse repairs performed with Apogee® or Perigee® mesh kits (IntePro® or IntePro Lite®) at a single centre over an 11-year period, with patients receiving ongoing annual follow-up. A sequential stepwise univariate and multivariate Cox regression analysis was performed to identify variables that were significantly associated with mesh exposure.

Results

Eighty-eight women with 113 mesh kits were reviewed from the original cohort of 158 women. The median length of follow-up was 6.4 years (range 1.1–12.5 years). Mesh exposure rate per implant in the IntePro® group was 16/40 (40%) versus 4/73 (5.5%) in the IntePro Lite® group (p < 0.0001). A hazard ratio of 4.2 was identified for mesh exposure for IntePro® versus IntePro Lite® (95% CI 3.0–6.8). There was no difference in rates of recurrent prolapse between the heavy- and lightweight mesh groups.

Conclusions

Lightweight transvaginal mesh is associated with lower mesh exposure rates than heavyweight mesh at a median follow-up of 6.4 years, with no difference in rates of recurrent prolapse.

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Titel: Lightweight transvaginal mesh is associated with lower mesh exposure rates than heavyweight mesh
verfasst von: Nicola Dykes
Debjyoti Karmakar
Lynsey Hayward
Publikationsdatum: 03.03.2020
Verlag: Springer International Publishing
Erschienen in: International Urogynecology Journal / Ausgabe 9/2020
Print ISSN: 0937-3462
Elektronische ISSN: 1433-3023
DOI: https://doi.org/10.1007/s00192-020-04270-z

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