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Erschienen in: Osteoporosis International 12/2012

01.12.2012 | Original Article

Burden of pelvis fracture: a population-based study of incidence, hospitalisation and mortality

verfasst von: D. Prieto-Alhambra, F. F. Avilés, A. Judge, T. Van Staa, X. Nogués, N. K. Arden, A. Díez-Pérez, C. Cooper, M. K. Javaid

Erschienen in: Osteoporosis International | Ausgabe 12/2012

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Abstract

Summary

The objective of this study was to describe the incidence and consequences of pelvic fractures in a community cohort. The incidence of pelvic fractures increases with age with a protective effect of higher body mass index. Almost 60% of those with a pelvic fracture required an inpatient stay, with a median of 9 days. There was a higher 3-year mortality in those admitted (17%) vs. those not admitted (6.3%). Given the substantial health burden, further work is required to identify the optimal post-fracture therapeutic strategy to improve outcomes.

Introduction

The burden of pelvis fractures is projected to increase, but there is a paucity of community-based studies describing rates, mortality and future fracture risk. We therefore estimated the age, gender and BMI-specific incidence of pelvis fracture in Catalonia (North-East Spain), and assessed hospital stay and mortality following fracture.

Methods

The SIDIAPQ database contains validated clinical information from computerised medical records of a representative sample of 30% of the population of Catalonia. We conducted a retrospective cohort study including all subjects aged ≥40 in SIDIAPQ and linked to the regional Hospital Admissions Database from 2007 to 2009. Pelvis fractures were ascertained using ICD-10 codes. Incidence and mortality rates were calculated.

Results

A total of 1,118,173 patients (582,820 women) were observed for 3 years and 1,356 had a pelvic fracture. The rate for pelvic fracture was 4.35/10,000 person-years (pyar) [95% CI 4.13–4.59] (men—2.73 [2.48–3.01]; women—5.82 [5.46–6.20]). This increased with age, peaking in those over 90 years: 29.41 [25.74–33.59]. Higher BMI was protective (HR 0.75 per SD BMI; [0.69–0.82]). Moreover, 59.1% of fractured patients were hospitalised with a median (IQR) stay of 9 (5–16) days, and after the 3-year follow-up 13.9% died (mortality rate 10.7/100 pyar [9.3–12.3]) with higher rates in those hospitalised (17.0%).

Conclusions

Pelvic fractures are associated with high rates of hospitalisation and mortality. Given this, further work is required to identify the optimal post-fracture therapeutic strategy to improve outcomes in this elderly patient group.
Literatur
1.
Zurück zum Zitat Morris RO, Sonibare A, Green DJ, Masud T (2000) Closed pelvic fractures: characteristics and outcomes in older patients admitted to medical and geriatric wards. Postgrad Med J 76:646–650PubMedCrossRef Morris RO, Sonibare A, Green DJ, Masud T (2000) Closed pelvic fractures: characteristics and outcomes in older patients admitted to medical and geriatric wards. Postgrad Med J 76:646–650PubMedCrossRef
2.
Zurück zum Zitat Pike C, Birnbaum HG, Schiller M, Sharma H, Burge R, Edgell ET (2010) Direct and indirect costs of non-vertebral fracture patients with osteoporosis in the US. PharmacoEconomics 28:395–409PubMedCrossRef Pike C, Birnbaum HG, Schiller M, Sharma H, Burge R, Edgell ET (2010) Direct and indirect costs of non-vertebral fracture patients with osteoporosis in the US. PharmacoEconomics 28:395–409PubMedCrossRef
3.
Zurück zum Zitat Islam S, Liu Q, Chines A, Helzner E (2009) Trend in incidence of osteoporosis-related fractures among 40- to 69-year-old women: analysis of a large insurance claims database, 2000–2005. Menopause 16:77–83PubMedCrossRef Islam S, Liu Q, Chines A, Helzner E (2009) Trend in incidence of osteoporosis-related fractures among 40- to 69-year-old women: analysis of a large insurance claims database, 2000–2005. Menopause 16:77–83PubMedCrossRef
4.
Zurück zum Zitat Parkkari J, Kannus P, Niemi S, Pasanen M, Jarvinen M, Luthje P, Vuori I (1996) Secular trends in osteoporotic pelvic fractures in Finland: number and incidence of fractures in 1970–1991 and prediction for the future. Calcif Tissue Int 59:79–83PubMedCrossRef Parkkari J, Kannus P, Niemi S, Pasanen M, Jarvinen M, Luthje P, Vuori I (1996) Secular trends in osteoporotic pelvic fractures in Finland: number and incidence of fractures in 1970–1991 and prediction for the future. Calcif Tissue Int 59:79–83PubMedCrossRef
5.
Zurück zum Zitat Krappinger D, Kammerlander C, Hak DJ, Blauth M (2010) Low-energy osteoporotic pelvic fractures. Arch Orthop Trauma Surg 130:1167–1175PubMedCrossRef Krappinger D, Kammerlander C, Hak DJ, Blauth M (2010) Low-energy osteoporotic pelvic fractures. Arch Orthop Trauma Surg 130:1167–1175PubMedCrossRef
6.
Zurück zum Zitat Boufous S, Finch C, Close J, Day L, Lord S (2007) Hospital admissions following presentations to emergency departments for a fracture in older people. Inj Prev 13:211–214PubMedCrossRef Boufous S, Finch C, Close J, Day L, Lord S (2007) Hospital admissions following presentations to emergency departments for a fracture in older people. Inj Prev 13:211–214PubMedCrossRef
7.
Zurück zum Zitat Ragnarsson B, Jacobsson B (1992) Epidemiology of pelvic fractures in a Swedish county. Acta Orthop Scand 63:297–300PubMedCrossRef Ragnarsson B, Jacobsson B (1992) Epidemiology of pelvic fractures in a Swedish county. Acta Orthop Scand 63:297–300PubMedCrossRef
8.
Zurück zum Zitat Garcia-Gil M, Hermosilla E, Prieto-Alhambra D, Fina F, Rossell M, Ramos R, Rodriguez J, Williams T, Van Staa T, Bolibar B (2011) Construction and validation of a scoring system for selction of high quality data in a Spanish population primary care database (SIDIAP). Informatics in Primary Care (in press) Garcia-Gil M, Hermosilla E, Prieto-Alhambra D, Fina F, Rossell M, Ramos R, Rodriguez J, Williams T, Van Staa T, Bolibar B (2011) Construction and validation of a scoring system for selction of high quality data in a Spanish population primary care database (SIDIAP). Informatics in Primary Care (in press)
9.
Zurück zum Zitat Ramos R, Balló E, Marrugat J, Elosúa R, Sala J, Grau M, Vila J, Bolíbar B, García-Gil M, Martí R, Fina F, Hermosilla E, Rossell M, Muñoz MA, Prieto-Alhambra D, Quesada M (2012) Validity for use in research on vascular diseases of the SIDIAP (Information System for the Development of Research in Primary Care): the EMMA Study. Rev Esp Cardiol 65(1):29–37 Ramos R, Balló E, Marrugat J, Elosúa R, Sala J, Grau M, Vila J, Bolíbar B, García-Gil M, Martí R, Fina F, Hermosilla E, Rossell M, Muñoz MA, Prieto-Alhambra D, Quesada M (2012) Validity for use in research on vascular diseases of the SIDIAP (Information System for the Development of Research in Primary Care): the EMMA Study. Rev Esp Cardiol 65(1):29–37
10.
Zurück zum Zitat Diez A, Puig J, Martinez MT, Diez JL, Aubia J, Vivancos J (1989) Epidemiology of fractures of the proximal femur associated with osteoporosis in Barcelona, Spain. Calcif Tissue Int 44:382–386PubMedCrossRef Diez A, Puig J, Martinez MT, Diez JL, Aubia J, Vivancos J (1989) Epidemiology of fractures of the proximal femur associated with osteoporosis in Barcelona, Spain. Calcif Tissue Int 44:382–386PubMedCrossRef
11.
Zurück zum Zitat Alvarez-Nebreda ML, Jimenez AB, Rodriguez P, Serra JA (2008) Epidemiology of hip fracture in the elderly in Spain. Bone 42:278–285PubMedCrossRef Alvarez-Nebreda ML, Jimenez AB, Rodriguez P, Serra JA (2008) Epidemiology of hip fracture in the elderly in Spain. Bone 42:278–285PubMedCrossRef
12.
Zurück zum Zitat IDESCAT (2011) Anuari Estadístic de Catalunya. Taxes de Mortalitat per grups d'edat i gènere. In Departament de Salut GdC (ed). Barcelona IDESCAT (2011) Anuari Estadístic de Catalunya. Taxes de Mortalitat per grups d'edat i gènere. In Departament de Salut GdC (ed). Barcelona
13.
Zurück zum Zitat Pohlemann T, Tosounidis G, Bircher M, Giannoudis P, Culemann U (2007) The German Multicentre Pelvis Registry: a template for an European Expert Network? Injury 38:416–423PubMedCrossRef Pohlemann T, Tosounidis G, Bircher M, Giannoudis P, Culemann U (2007) The German Multicentre Pelvis Registry: a template for an European Expert Network? Injury 38:416–423PubMedCrossRef
14.
Zurück zum Zitat Wubben RC (1996) Mortality rate of pelvic fracture patients. Wis Med J 95:702–704PubMed Wubben RC (1996) Mortality rate of pelvic fracture patients. Wis Med J 95:702–704PubMed
15.
Zurück zum Zitat Dodge G, Brison R (2010) Low-impact pelvic fractures in the emergency department. CJEM 12:509–513PubMed Dodge G, Brison R (2010) Low-impact pelvic fractures in the emergency department. CJEM 12:509–513PubMed
16.
Zurück zum Zitat Spaniolas K, Cheng JD, Gestring ML, Sangosanya A, Stassen NA, Bankey PE (2010) Ground level falls are associated with significant mortality in elderly patients. J Trauma 69:821–825PubMedCrossRef Spaniolas K, Cheng JD, Gestring ML, Sangosanya A, Stassen NA, Bankey PE (2010) Ground level falls are associated with significant mortality in elderly patients. J Trauma 69:821–825PubMedCrossRef
17.
Zurück zum Zitat Margolis KL, Ensrud KE, Schreiner PJ, Tabor HK (2000) Body size and risk for clinical fractures in older women. Study of Osteoporotic Fractures Research Group. Ann Intern Med 133:123–127PubMed Margolis KL, Ensrud KE, Schreiner PJ, Tabor HK (2000) Body size and risk for clinical fractures in older women. Study of Osteoporotic Fractures Research Group. Ann Intern Med 133:123–127PubMed
18.
Zurück zum Zitat Premaor MO, Pilbrow L, Tonkin C, Parker RA, Compston J (2010) Obesity and fractures in postmenopausal women. J Bone Miner Res 25:292–297PubMedCrossRef Premaor MO, Pilbrow L, Tonkin C, Parker RA, Compston J (2010) Obesity and fractures in postmenopausal women. J Bone Miner Res 25:292–297PubMedCrossRef
19.
Zurück zum Zitat Melton LJ, 3rd, Sampson JM, Morrey BF, Ilstrup DM (1981) Epidemiologic features of pelvic fractures. Clin Orthop Relat Res 43-47 Melton LJ, 3rd, Sampson JM, Morrey BF, Ilstrup DM (1981) Epidemiologic features of pelvic fractures. Clin Orthop Relat Res 43-47
20.
Zurück zum Zitat van Staa TP, Dennison EM, Leufkens HG, Cooper C (2001) Epidemiology of fractures in England and Wales. Bone 29:517–522PubMedCrossRef van Staa TP, Dennison EM, Leufkens HG, Cooper C (2001) Epidemiology of fractures in England and Wales. Bone 29:517–522PubMedCrossRef
21.
Zurück zum Zitat De Laet C, Kanis JA, Oden A, Johanson H, Johnell O, Delmas P, Eisman JA, Kroger H, Fujiwara S, Garnero P, McCloskey EV, Mellstrom D, Melton LJ 3rd, Meunier PJ, Pols HA, Reeve J, Silman A, Tenenhouse A (2005) Body mass index as a predictor of fracture risk: a meta-analysis. Osteoporos Int 16:1330–1338PubMedCrossRef De Laet C, Kanis JA, Oden A, Johanson H, Johnell O, Delmas P, Eisman JA, Kroger H, Fujiwara S, Garnero P, McCloskey EV, Mellstrom D, Melton LJ 3rd, Meunier PJ, Pols HA, Reeve J, Silman A, Tenenhouse A (2005) Body mass index as a predictor of fracture risk: a meta-analysis. Osteoporos Int 16:1330–1338PubMedCrossRef
22.
Zurück zum Zitat Kanis J, Johnell O, Gullberg B, Allander E, Elffors L, Ranstam J, Dequeker J, Dilsen G, Gennari C, Vaz AL, Lyritis G, Mazzuoli G, Miravet L, Passeri M, Perez Cano R, Rapado A, Ribot C (1999) Risk factors for hip fracture in men from southern Europe: the MEDOS study. Mediterranean Osteoporosis Study. Osteoporos Int 9:45–54PubMedCrossRef Kanis J, Johnell O, Gullberg B, Allander E, Elffors L, Ranstam J, Dequeker J, Dilsen G, Gennari C, Vaz AL, Lyritis G, Mazzuoli G, Miravet L, Passeri M, Perez Cano R, Rapado A, Ribot C (1999) Risk factors for hip fracture in men from southern Europe: the MEDOS study. Mediterranean Osteoporosis Study. Osteoporos Int 9:45–54PubMedCrossRef
23.
Zurück zum Zitat Burger HG, Dudley EC, Hopper JL, Groome N, Guthrie JR, Green A, Dennerstein L (1999) Prospectively measured levels of serum follicle-stimulating hormone, estradiol, and the dimeric inhibins during the menopausal transition in a population-based cohort of women. J Clin Endocrinol Metab 84:4025–4030PubMedCrossRef Burger HG, Dudley EC, Hopper JL, Groome N, Guthrie JR, Green A, Dennerstein L (1999) Prospectively measured levels of serum follicle-stimulating hormone, estradiol, and the dimeric inhibins during the menopausal transition in a population-based cohort of women. J Clin Endocrinol Metab 84:4025–4030PubMedCrossRef
24.
Zurück zum Zitat Randolph JF Jr, Zheng H, Sowers MR, Crandall C, Crawford S, Gold EB, Vuga M (2010) Change in follicle-stimulating hormone and estradiol across the menopausal transition: effect of age at the final menstrual period. J Clin Endocrinol Metab 96:746–754PubMedCrossRef Randolph JF Jr, Zheng H, Sowers MR, Crandall C, Crawford S, Gold EB, Vuga M (2010) Change in follicle-stimulating hormone and estradiol across the menopausal transition: effect of age at the final menstrual period. J Clin Endocrinol Metab 96:746–754PubMedCrossRef
25.
Zurück zum Zitat Ettinger B, Pressman A, Sklarin P, Bauer DC, Cauley JA, Cummings SR (1998) Associations between low levels of serum estradiol, bone density, and fractures among elderly women: the study of osteoporotic fractures. J Clin Endocrinol Metab 83:2239–2243PubMedCrossRef Ettinger B, Pressman A, Sklarin P, Bauer DC, Cauley JA, Cummings SR (1998) Associations between low levels of serum estradiol, bone density, and fractures among elderly women: the study of osteoporotic fractures. J Clin Endocrinol Metab 83:2239–2243PubMedCrossRef
26.
Zurück zum Zitat Beck TJ, Petit MA, Wu G, LeBoff MS, Cauley JA, Chen Z (2009) Does obesity really make the femur stronger? BMD, geometry, and fracture incidence in the women's health initiative—observational study. J Bone Miner Res 24:1369–1379PubMedCrossRef Beck TJ, Petit MA, Wu G, LeBoff MS, Cauley JA, Chen Z (2009) Does obesity really make the femur stronger? BMD, geometry, and fracture incidence in the women's health initiative—observational study. J Bone Miner Res 24:1369–1379PubMedCrossRef
27.
Zurück zum Zitat Becker DJ, Yun H, Kilgore ML, Curtis JR, Delzell E, Gary LC, Saag KG, Morrisey MA (2010) Health services utilization after fractures: evidence from Medicare. J Gerontol A Biol Sci Med Sci 65:1012–1020PubMedCrossRef Becker DJ, Yun H, Kilgore ML, Curtis JR, Delzell E, Gary LC, Saag KG, Morrisey MA (2010) Health services utilization after fractures: evidence from Medicare. J Gerontol A Biol Sci Med Sci 65:1012–1020PubMedCrossRef
28.
Zurück zum Zitat Breuil V, Roux CH, Testa J, Albert C, Chassang M, Brocq O, Euller-Ziegler L (2008) Outcome of osteoporotic pelvic fractures: an underestimated severity. Survey of 60 cases. Joint Bone Spine 75:585–588PubMedCrossRef Breuil V, Roux CH, Testa J, Albert C, Chassang M, Brocq O, Euller-Ziegler L (2008) Outcome of osteoporotic pelvic fractures: an underestimated severity. Survey of 60 cases. Joint Bone Spine 75:585–588PubMedCrossRef
29.
Zurück zum Zitat Krappinger D, Struve P, Schmid R, Kroesslhuber J, Blauth M (2009) Fractures of the pubic rami: a retrospective review of 534 cases. Arch Orthop Trauma Surg 129:1685–1690PubMedCrossRef Krappinger D, Struve P, Schmid R, Kroesslhuber J, Blauth M (2009) Fractures of the pubic rami: a retrospective review of 534 cases. Arch Orthop Trauma Surg 129:1685–1690PubMedCrossRef
30.
Zurück zum Zitat Bischoff-Ferrari HA, Dawson-Hughes B, Platz A, Orav EJ, Stahelin HB, Willett WC, Can U, Egli A, Mueller NJ, Looser S, Bretscher B, Minder E, Vergopoulos A, Theiler R (2010) Effect of high-dosage cholecalciferol and extended physiotherapy on complications after hip fracture: a randomized controlled trial. Arch Intern Med 170:813–820PubMedCrossRef Bischoff-Ferrari HA, Dawson-Hughes B, Platz A, Orav EJ, Stahelin HB, Willett WC, Can U, Egli A, Mueller NJ, Looser S, Bretscher B, Minder E, Vergopoulos A, Theiler R (2010) Effect of high-dosage cholecalciferol and extended physiotherapy on complications after hip fracture: a randomized controlled trial. Arch Intern Med 170:813–820PubMedCrossRef
31.
Zurück zum Zitat Deakin DE, Boulton C, Moran CG (2007) Mortality and causes of death among patients with isolated limb and pelvic fractures. Injury 38:312–317PubMedCrossRef Deakin DE, Boulton C, Moran CG (2007) Mortality and causes of death among patients with isolated limb and pelvic fractures. Injury 38:312–317PubMedCrossRef
32.
Zurück zum Zitat Rossvoll I, Finsen V (1989) Mortality after pelvic fractures in the elderly. J Orthop Trauma 3:115–117PubMedCrossRef Rossvoll I, Finsen V (1989) Mortality after pelvic fractures in the elderly. J Orthop Trauma 3:115–117PubMedCrossRef
33.
Zurück zum Zitat van Dijk WA, Poeze M, van Helden SH, Brink PR, Verbruggen JP (2010) Ten-year mortality among hospitalised patients with fractures of the pubic rami. Injury 41:411–414PubMedCrossRef van Dijk WA, Poeze M, van Helden SH, Brink PR, Verbruggen JP (2010) Ten-year mortality among hospitalised patients with fractures of the pubic rami. Injury 41:411–414PubMedCrossRef
34.
Zurück zum Zitat Hill RM, Robinson CM, Keating JF (2001) Fractures of the pubic rami. Epidemiology and five-year survival. J Bone Joint Surg Br 83:1141–1144PubMedCrossRef Hill RM, Robinson CM, Keating JF (2001) Fractures of the pubic rami. Epidemiology and five-year survival. J Bone Joint Surg Br 83:1141–1144PubMedCrossRef
35.
Zurück zum Zitat Taillandier J, Langue F, Alemanni M, Taillandier-Heriche E (2003) Mortality and functional outcomes of pelvic insufficiency fractures in older patients. Joint Bone Spine 70:287–289PubMedCrossRef Taillandier J, Langue F, Alemanni M, Taillandier-Heriche E (2003) Mortality and functional outcomes of pelvic insufficiency fractures in older patients. Joint Bone Spine 70:287–289PubMedCrossRef
36.
Zurück zum Zitat Rapp K, Becker C, Lamb SE, Icks A, Klenk J (2008) Hip fractures in institutionalized elderly people: incidence rates and excess mortality. J Bone Miner Res 23:1825–1831PubMedCrossRef Rapp K, Becker C, Lamb SE, Icks A, Klenk J (2008) Hip fractures in institutionalized elderly people: incidence rates and excess mortality. J Bone Miner Res 23:1825–1831PubMedCrossRef
Metadaten
Titel
Burden of pelvis fracture: a population-based study of incidence, hospitalisation and mortality
verfasst von
D. Prieto-Alhambra
F. F. Avilés
A. Judge
T. Van Staa
X. Nogués
N. K. Arden
A. Díez-Pérez
C. Cooper
M. K. Javaid
Publikationsdatum
01.12.2012
Verlag
Springer-Verlag
Erschienen in
Osteoporosis International / Ausgabe 12/2012
Print ISSN: 0937-941X
Elektronische ISSN: 1433-2965
DOI
https://doi.org/10.1007/s00198-012-1907-z

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