Skip to main content
Erschienen in: Abdominal Radiology 6/2007

01.11.2007

Sclerosing Hepatic Carcinoma: Helical CT Features

verfasst von: Seong Hyun Kim, Won Jae Lee, Hyo K. Lim, Cheol Keun Park

Erschienen in: Abdominal Radiology | Ausgabe 6/2007

Einloggen, um Zugang zu erhalten

Abstract

Background

The purpose of this study was to describe our experience, particularly for CT features, with four patients who had pathologically proven sclerosing hepatic carcinoma that mimicked other malignant hepatic tumors with abundant fibrosis at CT.

Methods

Over a 10-year period, we collected four patients with surgically proven sclerosing hepatic carcinoma. All patients were men (age range, 49–63 years; mean, 56 years). Three-phase helical CT images were obtained in all patients, and their CT features were correlated with pathologic findings.

Results

The tumor size ranged from 2.7 to 11 cm (mean, 7.2 cm). The tumors were manifested as a hypoattenuating mass with peripheral, rim enhancement at hepatic arterial phase, followed by centripetal enhancement progressively during portal venous and equilibrium phases. Histopathologically, the tumors showed features intermediate between hepatocellular carcinoma and cholangiocarcinoma with abundant fibrosis and surrounding liver had no liver cirrhosis.

Conclusion

As described above, the CT features of sclerosing hepatic carcinoma may be similar to other malignant hepatic tumors with abundant fibrosis. Although sclerosing hepatic carcinoma is extremely rare, the radiologists should recognize that this tumor may be one of the malignant hepatic tumors with abundant fibrosis, especially in the non-cirrhotic liver.
Literatur
1.
Zurück zum Zitat Omata M, Peters RL, Tatter D (1981) Sclerosing hepatic carcinoma: relationship to hypercalcimia. Liver 1:33–49PubMed Omata M, Peters RL, Tatter D (1981) Sclerosing hepatic carcinoma: relationship to hypercalcimia. Liver 1:33–49PubMed
2.
Zurück zum Zitat Park C, Park YN (1994) Immunohistochemical profile of sclerosing hepatic carcinoma. Korean J Pathol 28:636–642 Park C, Park YN (1994) Immunohistochemical profile of sclerosing hepatic carcinoma. Korean J Pathol 28:636–642
3.
Zurück zum Zitat Llovet JM, Miquel R (1999) Sclerosing hepatic carcinoma in non-cirrhotic liver resembling metastatic adenocarcinoma. J Hepatol 30:161PubMedCrossRef Llovet JM, Miquel R (1999) Sclerosing hepatic carcinoma in non-cirrhotic liver resembling metastatic adenocarcinoma. J Hepatol 30:161PubMedCrossRef
4.
Zurück zum Zitat MacSween RNM, Burt AD, Portmann BC, et al. (2002) Pathology of the liver, 4th ed. London: Churchill Livingstone, pp 711–775 MacSween RNM, Burt AD, Portmann BC, et al. (2002) Pathology of the liver, 4th ed. London: Churchill Livingstone, pp 711–775
5.
Zurück zum Zitat Kim H, Park C, Han KH, et al. (2004) Primary liver carcinoma of intermediate (hepatocyte-cholangiocyte) phenotype. J Hepatol 40:298–304PubMedCrossRef Kim H, Park C, Han KH, et al. (2004) Primary liver carcinoma of intermediate (hepatocyte-cholangiocyte) phenotype. J Hepatol 40:298–304PubMedCrossRef
6.
Zurück zum Zitat Maeda A, Ebata T, Matsunaga K, et al. (2005) Primary liver cancer with bidirectional differentiation into hepatocytes and biliary epithelium. J Hepatobiliary Pancreat Surg 12:484–487PubMedCrossRef Maeda A, Ebata T, Matsunaga K, et al. (2005) Primary liver cancer with bidirectional differentiation into hepatocytes and biliary epithelium. J Hepatobiliary Pancreat Surg 12:484–487PubMedCrossRef
7.
Zurück zum Zitat Wu P, Lai V, Fang J, et al. (1996) Classification of hepatocellular carcinoma according to hepatocellular and biliary differentiation markers: clinical and biological implications. Am J Pathol 149:1167–1175PubMed Wu P, Lai V, Fang J, et al. (1996) Classification of hepatocellular carcinoma according to hepatocellular and biliary differentiation markers: clinical and biological implications. Am J Pathol 149:1167–1175PubMed
8.
Zurück zum Zitat Robrechts C, De Vos R, Van den Heuvel M, et al. (1998) Primary liver tumor of intermediate (hepatocyte-bile duct cell) phenotype: a progenitor cell tumour? Liver 18:288–293PubMed Robrechts C, De Vos R, Van den Heuvel M, et al. (1998) Primary liver tumor of intermediate (hepatocyte-bile duct cell) phenotype: a progenitor cell tumour? Liver 18:288–293PubMed
9.
Zurück zum Zitat Matsuura S, Aishima S, Taguchi K, et al. (2005) ‘Scirrhous’ type hepatocellular carcinomas: a special reference to expression of cytokeratin 7 and hepatocyte paraffin 1. Histopathology 47:382–390PubMedCrossRef Matsuura S, Aishima S, Taguchi K, et al. (2005) ‘Scirrhous’ type hepatocellular carcinomas: a special reference to expression of cytokeratin 7 and hepatocyte paraffin 1. Histopathology 47:382–390PubMedCrossRef
10.
Zurück zum Zitat Yoshikawa J, Matsui O, Kadoya M, et al. (1992) Delayed enhancement of fibrotic areas in hepatic masses: CT-pathologic correlation. J Comput Assist Tomogr 16:206–211PubMedCrossRef Yoshikawa J, Matsui O, Kadoya M, et al. (1992) Delayed enhancement of fibrotic areas in hepatic masses: CT-pathologic correlation. J Comput Assist Tomogr 16:206–211PubMedCrossRef
11.
Zurück zum Zitat Yamashita Y, Fan ZM, Yamamoto H, et al. (1993) Sclerosing hepatocellular carcinoma: radiologic findings. Abdom Imaging 18:347–351PubMedCrossRef Yamashita Y, Fan ZM, Yamamoto H, et al. (1993) Sclerosing hepatocellular carcinoma: radiologic findings. Abdom Imaging 18:347–351PubMedCrossRef
12.
Zurück zum Zitat Hong T, Lee R, Chiang J, Chang C (2001) Centrally-located sclerosing hepatocellular carcinoma: a case report with imaging findings before and after transcatheter arterial chemoembolization. Chin J Radiol 26:147–152 Hong T, Lee R, Chiang J, Chang C (2001) Centrally-located sclerosing hepatocellular carcinoma: a case report with imaging findings before and after transcatheter arterial chemoembolization. Chin J Radiol 26:147–152
13.
Zurück zum Zitat Blachar A, Federle MP, Brancatelli G (2002) Hepatic capsular retraction: spectrum of benign and malignant etiologies. Abdom Imaging 27:690–699PubMedCrossRef Blachar A, Federle MP, Brancatelli G (2002) Hepatic capsular retraction: spectrum of benign and malignant etiologies. Abdom Imaging 27:690–699PubMedCrossRef
Metadaten
Titel
Sclerosing Hepatic Carcinoma: Helical CT Features
verfasst von
Seong Hyun Kim
Won Jae Lee
Hyo K. Lim
Cheol Keun Park
Publikationsdatum
01.11.2007
Verlag
Springer-Verlag
Erschienen in
Abdominal Radiology / Ausgabe 6/2007
Print ISSN: 2366-004X
Elektronische ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-006-9174-0

Weitere Artikel der Ausgabe 6/2007

Abdominal Radiology 6/2007 Zur Ausgabe

PET kann infarktgefährdete Koronararterien entdecken

04.06.2024 Koronare Herzerkrankung Nachrichten

Der Nachweis aktiver Plaques mittels 18F-Natriumfluorid-PET hilft nicht nur, infarktgefährdete Patienten, sondern auch infarktgefährdete Koronararterien zu erkennen. Von einer gezielten Behandlung vulnerabler Plaques ist man trotzdem weit entfernt.

Mammakarzinom: Brustdichte beeinflusst rezidivfreies Überleben

26.05.2024 Mammakarzinom Nachrichten

Frauen, die zum Zeitpunkt der Brustkrebsdiagnose eine hohe mammografische Brustdichte aufweisen, haben ein erhöhtes Risiko für ein baldiges Rezidiv, legen neue Daten nahe.

„Übersichtlicher Wegweiser“: Lauterbachs umstrittener Klinik-Atlas ist online

17.05.2024 Klinik aktuell Nachrichten

Sie sei „ethisch geboten“, meint Gesundheitsminister Karl Lauterbach: mehr Transparenz über die Qualität von Klinikbehandlungen. Um sie abzubilden, lässt er gegen den Widerstand vieler Länder einen virtuellen Klinik-Atlas freischalten.

Klinikreform soll zehntausende Menschenleben retten

15.05.2024 Klinik aktuell Nachrichten

Gesundheitsminister Lauterbach hat die vom Bundeskabinett beschlossene Klinikreform verteidigt. Kritik an den Plänen kommt vom Marburger Bund. Und in den Ländern wird über den Gang zum Vermittlungsausschuss spekuliert.

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.