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01.08.2015 | Nuclear Medicine

PET/MRI and PET/CT in advanced gynaecological tumours: initial experience and comparison

verfasst von: Marcelo A. Queiroz, Rahel A. Kubik-Huch, Nik Hauser, Bianka Freiwald-Chilla, Gustav von Schulthess, Johannes M. Froehlich, Patrick Veit-Haibach

Erschienen in: European Radiology | Ausgabe 8/2015

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Abstract

Purpose

To compare the diagnostic accuracy of PET/MRI and PET/CT for staging and re-staging advanced gynaecological cancer patients as well as identify the potential benefits of each method in such a population.

Material and methods

Twenty-six patients with suspicious or proven advanced gynaecological cancer (12 ovarian, seven cervical, one vulvar and four endometrial tumours, one uterine metastasis, and one primary peritoneal cancer) underwent whole-body imaging with a sequential trimodality PET/CT/MR system. Images were analysed regarding primary tumour detection and delineation, loco-regional lymph node staging, and abdominal/extra-abdominal distant metastasis detection (last only by PET/CT).

Results

Eighteen (69.2 %) patients underwent PET/MRI for primary staging and eight patients (30.8 %) for re-staging their gynaecological malignancies. For primary tumour delineation, PET/MRI accuracy was statistically superior to PET/CT (p < 0.001). Among the different types of cancer, PET/MRI presented better tumour delineation mainly for cervical (6/7) and endometrial (2/3) cancers. PET/MRI for local evaluation as well as PET/CT for extra-abdominal metastases had therapeutic consequences in three and one patients, respectively. PET/CT detected 12 extra-abdominal distant metastases in 26 patients.

Conclusion

PET/MRI is superior to PET/CT for primary tumour delineation. No differences were found in detection of regional lymph node involvement and abdominal metastases detection.

Key Points

• PET/MRI is superior to PET/CT for primary tumour delineation

• PET/CT represents a reliable tool to detect extra-abdominal distant metastasis

• PET/MRI might be the preferred imaging modality for staging cervical and endometrial tumours

• Whole-body staging for detection and evaluation of extra-abdominal metastases is mandatory

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Titel: PET/MRI and PET/CT in advanced gynaecological tumours: initial experience and comparison
verfasst von: Marcelo A. Queiroz
Rahel A. Kubik-Huch
Nik Hauser
Bianka Freiwald-Chilla
Gustav von Schulthess
Johannes M. Froehlich
Patrick Veit-Haibach
Publikationsdatum: 01.08.2015
Verlag: Springer Berlin Heidelberg
Erschienen in: European Radiology / Ausgabe 8/2015
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-015-3657-8

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PET/MRI and PET/CT in advanced gynaecological tumours: initial experience and comparison