Skip to main content
Erschienen in: Child's Nervous System 1/2017

06.08.2016 | Original Paper

Proposed caudal appendage classification system; spinal cord tethering associated with sacrococcygeal eversion

verfasst von: C. Corbett Wilkinson, Arianne J Boylan

Erschienen in: Child's Nervous System | Ausgabe 1/2017

Einloggen, um Zugang zu erhalten

Abstract

Introduction

The most commonly used classification system for caudal appendages (aka human tails) dates from the 1980s and classifies appendages (tails) as either true tails or pseudotails. Advances in neuroimaging since the 1980s, however, as well as an ever-increasing number of reported cases, have made this system outdated. Sacrococcygeal eversion is a condition in which the distal sacral and coccygeal vertebrae are curved in a retroverted rather than anteverted direction. It can give rise to one type of caudal appendage. Sacrococcygeal eversion has never been associated with spinal cord tethering in any previously published reports.

Methods

We reviewed all cases of caudal appendage encountered by pediatric neurosurgeons at Children’s Hospital Colorado since 2000 in which the appendage would be classified as a true tail by the most commonly used system mentioned above. We also reviewed cases of sacrococcygeal eversion encountered since 2000 by the same group of pediatric neurosurgeons. We searched the hospital electronic medical record system for additional appendages using the terms “caudal appendage” and “persistent human tail.”

Results

We found 9 “true” tails (as classified by the most commonly used system). All 9 were associated with tethering or possible tethering of the spinal cord and 6 were associated with a low-lying conus medullaris. There were 8 cases of sacrococcygeal eversion, including 2 associated with Apert or Pfeiffer syndrome and fibroblast growth factor receptor 2 (FGFR2) mutations; these have previously been reported. There was a single case of sacrococcygeal eversion associated with Goldenhar or Turner syndrome; the former was associated with a potentially tethering lesion. Four cases of sacrococcygeal eversion not associated with any known syndrome were also found; two of these were associated with tethering or potentially tethering lesions.

Conclusions

Most so-called true tails are likely cutaneous markers for spinal dysraphism and spinal cord tethering and are not remnants of the embryonic human tail. Sacrococcygeal eversion can be associated with spinal cord tethering. Based on our cases, and on review of the literature, we devised a five-category classification system for caudal appendages: (1) soft-tissue caudal appendages, (2) bony caudal appendages, (3) bony caudal prominences, (4) true tails, and (5) “other” caudal appendages.
Literatur
1.
Zurück zum Zitat Bartels M (1884) Die geschwanzten Menschen. Arch Anthropol 15:45–132 Bartels M (1884) Die geschwanzten Menschen. Arch Anthropol 15:45–132
2.
Zurück zum Zitat Virchow R (1880) Über Schwanzbildung beim Menschen. Virchows Arch Pathol Anat Physiol 79:176–182CrossRef Virchow R (1880) Über Schwanzbildung beim Menschen. Virchows Arch Pathol Anat Physiol 79:176–182CrossRef
6.
Zurück zum Zitat Wilkinson CC, Manchester DK, Keating RF, Ketch LL, Winston KW (2012) Syndromic craniosynostosis, fibroblast growth factor 2 (FGFR2) mutations, and sacrococcygeal eversion presenting as human tails. Childs Nerv Syst 28:1221–1226PubMedCrossRef Wilkinson CC, Manchester DK, Keating RF, Ketch LL, Winston KW (2012) Syndromic craniosynostosis, fibroblast growth factor 2 (FGFR2) mutations, and sacrococcygeal eversion presenting as human tails. Childs Nerv Syst 28:1221–1226PubMedCrossRef
7.
Zurück zum Zitat Fallon JF, Simandl BK (1978) Evidence of a role for cell death in the disappearance of the embryonic human tail. Am J Anat 152:111–129PubMedCrossRef Fallon JF, Simandl BK (1978) Evidence of a role for cell death in the disappearance of the embryonic human tail. Am J Anat 152:111–129PubMedCrossRef
8.
Zurück zum Zitat Darwin C (1874) The descent of man and selection in relation to sex, Second edn. Rand McNally, ChicagoCrossRef Darwin C (1874) The descent of man and selection in relation to sex, Second edn. Rand McNally, ChicagoCrossRef
9.
Zurück zum Zitat Lundberg GD, Parsons RW (1962) A case of a human tail. Am J Dis Child 104:72–73PubMed Lundberg GD, Parsons RW (1962) A case of a human tail. Am J Dis Child 104:72–73PubMed
10.
Zurück zum Zitat Standfast AL (1992) The human tail. NY State J Med 92:116 Standfast AL (1992) The human tail. NY State J Med 92:116
11.
12.
Zurück zum Zitat Lin P-J, Chang Y-T, Tseng H-I, Lin J-Y, Huang Y-S (2007) Human tail and myelomeningocele. Pediatr Neurosurg 43:334–337PubMedCrossRef Lin P-J, Chang Y-T, Tseng H-I, Lin J-Y, Huang Y-S (2007) Human tail and myelomeningocele. Pediatr Neurosurg 43:334–337PubMedCrossRef
13.
Zurück zum Zitat Cai C, Shi O, Shen C (2011) Surgical treatment of a patient with human tail and multiple abnormalities of the spinal cord and spinal column. Adv Orthop. doi:10.4061/2011/153797 PubMed Cai C, Shi O, Shen C (2011) Surgical treatment of a patient with human tail and multiple abnormalities of the spinal cord and spinal column. Adv Orthop. doi:10.​4061/​2011/​153797 PubMed
14.
Zurück zum Zitat Harrison RG (1901) On the occurrence of tails in man, with a description of the case reported by Dr. Watson Johns Hopkins Hosp Bull 12:96–101 Harrison RG (1901) On the occurrence of tails in man, with a description of the case reported by Dr. Watson Johns Hopkins Hosp Bull 12:96–101
15.
Zurück zum Zitat Rijsbosch JKC (1977) Tail formation in man: some historical notes on a case report. Arch Chir Neerl 29:261–268PubMed Rijsbosch JKC (1977) Tail formation in man: some historical notes on a case report. Arch Chir Neerl 29:261–268PubMed
16.
Zurück zum Zitat Tavafoghi V, Ghandchi A, Hambrick GW, Udverhelyi GB (1978) Cutaneous signs of spinal dysraphism: report of a patient with a tail-like lipoma and review of 200 cases in the literature. Arch Dermatol 114:573–577PubMedCrossRef Tavafoghi V, Ghandchi A, Hambrick GW, Udverhelyi GB (1978) Cutaneous signs of spinal dysraphism: report of a patient with a tail-like lipoma and review of 200 cases in the literature. Arch Dermatol 114:573–577PubMedCrossRef
18.
Zurück zum Zitat Spiegelman R, Schinder E, Mintz M, Blakstein A (1985) The human tail: a benign stigma. J Neurosurg 63:461–462CrossRef Spiegelman R, Schinder E, Mintz M, Blakstein A (1985) The human tail: a benign stigma. J Neurosurg 63:461–462CrossRef
19.
Zurück zum Zitat Aso M, Kawaguchi T, Mihara M, Shimao S, Morimoto K, Sakinaga Y (1987) Pseudotail associated with spinal dysraphism. Dermatologica 174:45–48PubMedCrossRef Aso M, Kawaguchi T, Mihara M, Shimao S, Morimoto K, Sakinaga Y (1987) Pseudotail associated with spinal dysraphism. Dermatologica 174:45–48PubMedCrossRef
21.
Zurück zum Zitat James HE, Canty TG (1995) Human tails and associated spinal anomalies. Clin Pediatr (Phila) 34:286–288CrossRef James HE, Canty TG (1995) Human tails and associated spinal anomalies. Clin Pediatr (Phila) 34:286–288CrossRef
23.
Zurück zum Zitat Muthukumar N (2004) The “human tail”: a rare cause of tethered cord. Spine 29:E476–E478PubMedCrossRef Muthukumar N (2004) The “human tail”: a rare cause of tethered cord. Spine 29:E476–E478PubMedCrossRef
24.
Zurück zum Zitat Samura K, Morioka T, Hashiguchi K, Yoshida F, Miyagi Y, Yoshiura T, Suzuki SO, Sasaki T (2009) Coexistence of a human tail and congenital dermal sinus associated with lumbosacral lipoma. Childs Nerv Syst 25:137–141PubMedCrossRef Samura K, Morioka T, Hashiguchi K, Yoshida F, Miyagi Y, Yoshiura T, Suzuki SO, Sasaki T (2009) Coexistence of a human tail and congenital dermal sinus associated with lumbosacral lipoma. Childs Nerv Syst 25:137–141PubMedCrossRef
25.
Zurück zum Zitat Salunke P, Sura S, Tripathi M, Mukherjee K (2011) Human tail continuing as transitional lipoma. Neurol India 59:637–638PubMedCrossRef Salunke P, Sura S, Tripathi M, Mukherjee K (2011) Human tail continuing as transitional lipoma. Neurol India 59:637–638PubMedCrossRef
26.
Zurück zum Zitat Shad J, Biswas R (2012) An infant with caudal appendage. BMJ Case Reports. doi:10. 1136/bcr.11.2011.5160, Published 2012 Shad J, Biswas R (2012) An infant with caudal appendage. BMJ Case Reports. doi:10. 1136/bcr.11.2011.5160, Published 2012
27.
Zurück zum Zitat Theiler K (1959) Anatomy and development of the “truncate” (boneless) mutation in the mouse. Am J Anat 104:319–343PubMedCrossRef Theiler K (1959) Anatomy and development of the “truncate” (boneless) mutation in the mouse. Am J Anat 104:319–343PubMedCrossRef
28.
Zurück zum Zitat Gaskill SJ, Marlin AE (1989) Neuroectodermal appendages: the human tail explained. Pediatr Neurosci 15:95–99PubMedCrossRef Gaskill SJ, Marlin AE (1989) Neuroectodermal appendages: the human tail explained. Pediatr Neurosci 15:95–99PubMedCrossRef
29.
Zurück zum Zitat Mohindra S (2007) The “human tail” causing tethered cervical cord. Spinal Cord 45:583–585PubMedCrossRef Mohindra S (2007) The “human tail” causing tethered cervical cord. Spinal Cord 45:583–585PubMedCrossRef
30.
Zurück zum Zitat Erşahin Y, Gezen F, Baysefer A, Bedük A (1993) Neuroectodermal appendage: a case report and review. Turk Neurosurg 3:25–27 Erşahin Y, Gezen F, Baysefer A, Bedük A (1993) Neuroectodermal appendage: a case report and review. Turk Neurosurg 3:25–27
31.
Zurück zum Zitat Venkataramana N, Rao S, Naik A, Awasthy N, Gupta H, Sharma S (2008) The tale of a tail. J Pediatr Neurosci 3:142–145CrossRef Venkataramana N, Rao S, Naik A, Awasthy N, Gupta H, Sharma S (2008) The tale of a tail. J Pediatr Neurosci 3:142–145CrossRef
32.
Zurück zum Zitat Yamada S, Mandybur GT, Thompson JR (1996) Dorsal midline proboscosis associated with diastematomyelia and tethered cord syndrome. J Neurosurg 85:709–712PubMedCrossRef Yamada S, Mandybur GT, Thompson JR (1996) Dorsal midline proboscosis associated with diastematomyelia and tethered cord syndrome. J Neurosurg 85:709–712PubMedCrossRef
33.
Zurück zum Zitat Belzberg AJ, Myles ST, Trevenen CL (1991) The human tail and spinal dysraphism. J Pediatr Surg 26:1243–1245PubMedCrossRef Belzberg AJ, Myles ST, Trevenen CL (1991) The human tail and spinal dysraphism. J Pediatr Surg 26:1243–1245PubMedCrossRef
34.
Zurück zum Zitat Matsumoto S, Yamamoto T, Okura K (1994) Human tail associated with lipomeningocele. Neurol Med Chir (Tokyo) 34:44–47CrossRef Matsumoto S, Yamamoto T, Okura K (1994) Human tail associated with lipomeningocele. Neurol Med Chir (Tokyo) 34:44–47CrossRef
35.
Zurück zum Zitat Wright JD, Marder SJ, Geevarghese S, Shumway JB (2004) Prenatally diagnosed human caudal appendage. J Reprod Med 49:566–568PubMed Wright JD, Marder SJ, Geevarghese S, Shumway JB (2004) Prenatally diagnosed human caudal appendage. J Reprod Med 49:566–568PubMed
36.
Zurück zum Zitat Donovan DJ, Pedersen RC (2005) Human tail with noncontiguous intraspinal lipoma and spinal cord tethering: case report and embryologic discussion. Pediatr Neurosurg 41:35–40PubMedCrossRef Donovan DJ, Pedersen RC (2005) Human tail with noncontiguous intraspinal lipoma and spinal cord tethering: case report and embryologic discussion. Pediatr Neurosurg 41:35–40PubMedCrossRef
37.
Zurück zum Zitat Farook S, O’Kane R, Tyagi A (2008) Tale of a human tail: case report of a torted human tail. Br J Neurosurg 22:135–136PubMedCrossRef Farook S, O’Kane R, Tyagi A (2008) Tale of a human tail: case report of a torted human tail. Br J Neurosurg 22:135–136PubMedCrossRef
38.
Zurück zum Zitat Herman TE, Siegel MJ (2008) Human tail—caudal appendage: tethered cord. J Perinatol 28:518–519PubMedCrossRef Herman TE, Siegel MJ (2008) Human tail—caudal appendage: tethered cord. J Perinatol 28:518–519PubMedCrossRef
39.
Zurück zum Zitat Singh DK, Kumar B, Sinha VD, Bagaria HR (2008) The human tail: rare lesion with occult spinal dysraphism—a case report. J Pediatr Surg 43:E41–E43PubMedCrossRef Singh DK, Kumar B, Sinha VD, Bagaria HR (2008) The human tail: rare lesion with occult spinal dysraphism—a case report. J Pediatr Surg 43:E41–E43PubMedCrossRef
40.
Zurück zum Zitat Ohhara Y (1980) Human tails and other abnormalities of the lumbosacral region related to tethered cord syndrome. Ann Plast Surg 4:507–510PubMedCrossRef Ohhara Y (1980) Human tails and other abnormalities of the lumbosacral region related to tethered cord syndrome. Ann Plast Surg 4:507–510PubMedCrossRef
41.
Zurück zum Zitat Gönül E, İzci Y, Öngürü Ö, Timurkaynak E, Seber N (2000) The human tail associated with intraspinal lipoma: case report. Minim Invasive Neurosurg 43:215–218PubMedCrossRef Gönül E, İzci Y, Öngürü Ö, Timurkaynak E, Seber N (2000) The human tail associated with intraspinal lipoma: case report. Minim Invasive Neurosurg 43:215–218PubMedCrossRef
42.
Zurück zum Zitat Alexiou GA, Sfakianos G, Prodromou N (2009) Human tail and spinal dysraphism. J Pediatr Surg 44:477–478PubMedCrossRef Alexiou GA, Sfakianos G, Prodromou N (2009) Human tail and spinal dysraphism. J Pediatr Surg 44:477–478PubMedCrossRef
43.
Zurück zum Zitat Puvabanditsin S, Garrow E, Gowda S, Joshi-Kale M, Mehta R (2012) A gelatinous human tail with lipomyelocele: case report. J Child Neurol 28:124–127PubMedCrossRef Puvabanditsin S, Garrow E, Gowda S, Joshi-Kale M, Mehta R (2012) A gelatinous human tail with lipomyelocele: case report. J Child Neurol 28:124–127PubMedCrossRef
44.
Zurück zum Zitat Chauhan SPS, Gopal NN, Jain M, Gupta A (2009) Human tail with spina bifida. Br J Neurosurg 23:634–635PubMedCrossRef Chauhan SPS, Gopal NN, Jain M, Gupta A (2009) Human tail with spina bifida. Br J Neurosurg 23:634–635PubMedCrossRef
45.
Zurück zum Zitat Akhil P, Ashutosh N, Fais F, Shashank M, Sanjay P, Singhal BM, Attri PC, Arvind G (2010) True vestigeal tail with lumbosacral meningomyelocoel: a rare case report. Br J Neurosurg 24:597–599PubMedCrossRef Akhil P, Ashutosh N, Fais F, Shashank M, Sanjay P, Singhal BM, Attri PC, Arvind G (2010) True vestigeal tail with lumbosacral meningomyelocoel: a rare case report. Br J Neurosurg 24:597–599PubMedCrossRef
46.
Zurück zum Zitat Pang D, Zovickian J, Wong S-T, Hou YJ, Moes GS (2013) Limited dorsal myeloschisis: a not-so-rare form of primary neurulation defect. Childs Nerv Syst 29:1459–1484PubMedCrossRef Pang D, Zovickian J, Wong S-T, Hou YJ, Moes GS (2013) Limited dorsal myeloschisis: a not-so-rare form of primary neurulation defect. Childs Nerv Syst 29:1459–1484PubMedCrossRef
48.
49.
50.
Zurück zum Zitat Abbott JF, Davis GH, Endicott B, Pfleghaar K, Wapner RJ (1992) Prenatal diagnosis of vestigial tail. J Ultrasound Med 11:53–55PubMedCrossRef Abbott JF, Davis GH, Endicott B, Pfleghaar K, Wapner RJ (1992) Prenatal diagnosis of vestigial tail. J Ultrasound Med 11:53–55PubMedCrossRef
51.
Zurück zum Zitat Dubrow TJ, Wackym PA, Lesavoy MA (1988) Detailing the human tail. Ann Plast Surg 20:340–344PubMedCrossRef Dubrow TJ, Wackym PA, Lesavoy MA (1988) Detailing the human tail. Ann Plast Surg 20:340–344PubMedCrossRef
52.
Zurück zum Zitat Kabra NS, Srinivasan G, Udani RH (1999) True tail in a neonate. Indian Pediatr 36:712–713PubMed Kabra NS, Srinivasan G, Udani RH (1999) True tail in a neonate. Indian Pediatr 36:712–713PubMed
53.
Zurück zum Zitat Baruchin AM, Mahler D, Hauben DJ, Rosenberg L (1983) The human caudal appendage (human tail). Br J Plast Surg 36:120–123PubMedCrossRef Baruchin AM, Mahler D, Hauben DJ, Rosenberg L (1983) The human caudal appendage (human tail). Br J Plast Surg 36:120–123PubMedCrossRef
55.
56.
Zurück zum Zitat Fára M, Šmahel J (1973) Human tail. Acta Chir Plast 15:184–189PubMed Fára M, Šmahel J (1973) Human tail. Acta Chir Plast 15:184–189PubMed
57.
Zurück zum Zitat Amirjamshidi A, Abbassioun K, Shirani Bidabadi M (2006) Skin-covered midline spinal anomalies: a report of four rare cases with a discussion on their genesis and milestones in surgical management. Childs Nerv Syst 22:460–465PubMedCrossRef Amirjamshidi A, Abbassioun K, Shirani Bidabadi M (2006) Skin-covered midline spinal anomalies: a report of four rare cases with a discussion on their genesis and milestones in surgical management. Childs Nerv Syst 22:460–465PubMedCrossRef
59.
Zurück zum Zitat Walker AE, Bucy PC (1934) Congenital dermal sinuses: a source of spinal meningeal infection and subdural abscesses. Brain 57:401–421CrossRef Walker AE, Bucy PC (1934) Congenital dermal sinuses: a source of spinal meningeal infection and subdural abscesses. Brain 57:401–421CrossRef
60.
61.
Zurück zum Zitat Dickinson RL (1894) A child with a tail. Brooklyn Med J 8:568–569 Dickinson RL (1894) A child with a tail. Brooklyn Med J 8:568–569
62.
Zurück zum Zitat Bai DM, Kalidasan V, Govindarajan R, Shanbhogue HR (1993) Human tails. Pediatr Surg Int 9:133–134 Bai DM, Kalidasan V, Govindarajan R, Shanbhogue HR (1993) Human tails. Pediatr Surg Int 9:133–134
63.
Zurück zum Zitat Falzoni P, Boldorini R, Zilioli M, Sorrentino G (1995) The human tail: report of a case of coccygeal retroposition. Minerva Pediatr 47:489–491PubMed Falzoni P, Boldorini R, Zilioli M, Sorrentino G (1995) The human tail: report of a case of coccygeal retroposition. Minerva Pediatr 47:489–491PubMed
64.
Zurück zum Zitat Bar-Maor JA, Kesner KM, Kaftori JK (1980) Human tails. J Bone Joint Surg Brit 62-B:508–510PubMed Bar-Maor JA, Kesner KM, Kaftori JK (1980) Human tails. J Bone Joint Surg Brit 62-B:508–510PubMed
65.
66.
Zurück zum Zitat Sugamata A, Sato M, Ikeda J, Kinosita J, Tanihira S, Makino K (1988) Two cases of a true human tail. Jpn J Plast Reconstr Surg 31:1072 Sugamata A, Sato M, Ikeda J, Kinosita J, Tanihira S, Makino K (1988) Two cases of a true human tail. Jpn J Plast Reconstr Surg 31:1072
67.
Zurück zum Zitat Chakrabortty S, Oi S, Yoshida Y, Yamada H, Yamaguchi M, Tamaki N, Matsumoto S (1993) Myelomeningocele and thick filum terminale with tethered cord appearing as a human tail. J Neurosurg 78:966–969PubMedCrossRef Chakrabortty S, Oi S, Yoshida Y, Yamada H, Yamaguchi M, Tamaki N, Matsumoto S (1993) Myelomeningocele and thick filum terminale with tethered cord appearing as a human tail. J Neurosurg 78:966–969PubMedCrossRef
68.
Zurück zum Zitat Rijsbosch JKC (1960) Tail formation in man. Arch Chir Neerl 12:216–219PubMed Rijsbosch JKC (1960) Tail formation in man. Arch Chir Neerl 12:216–219PubMed
69.
70.
Zurück zum Zitat Ikpeze OC, Onuigbo WIB (1999) A bisegmented human tail in an African baby. Br J Plast Surg 52:329–330PubMed Ikpeze OC, Onuigbo WIB (1999) A bisegmented human tail in an African baby. Br J Plast Surg 52:329–330PubMed
71.
72.
Zurück zum Zitat Muthukumar N (2014) A bony tail causing tethered cord syndrome: case report. Childs Nerv Syst 30:703–707PubMedCrossRef Muthukumar N (2014) A bony tail causing tethered cord syndrome: case report. Childs Nerv Syst 30:703–707PubMedCrossRef
74.
Zurück zum Zitat Krishna A, Chandna S, Mishra NK, Gupta AK, Upadhyaya P (1989) Accessory limb associated with spina bifida. J Pediatr Surg 24:604–606CrossRef Krishna A, Chandna S, Mishra NK, Gupta AK, Upadhyaya P (1989) Accessory limb associated with spina bifida. J Pediatr Surg 24:604–606CrossRef
75.
Zurück zum Zitat Humphreys RP, Manwaring KH, Carroll NC (1991) Accessory arm—dysraphism or disparity? J Neurosurg 74:297–300PubMedCrossRef Humphreys RP, Manwaring KH, Carroll NC (1991) Accessory arm—dysraphism or disparity? J Neurosurg 74:297–300PubMedCrossRef
76.
Zurück zum Zitat Parkinson D (1991) Accessory limbs and spinal dysraphism. J Neurosurg 75:498–499PubMed Parkinson D (1991) Accessory limbs and spinal dysraphism. J Neurosurg 75:498–499PubMed
77.
Zurück zum Zitat Nanni L, Perreli L, Velardi F (1994) Accessory lower limb in a newborn with multiple malformations. Eur J Pediatr Surg 4:51–53PubMedCrossRef Nanni L, Perreli L, Velardi F (1994) Accessory lower limb in a newborn with multiple malformations. Eur J Pediatr Surg 4:51–53PubMedCrossRef
78.
Zurück zum Zitat Krishna A, Lal P (1999) Accessory limbs associated with spina bifida—a second look. Pediatr Surg Int 15:248–250PubMedCrossRef Krishna A, Lal P (1999) Accessory limbs associated with spina bifida—a second look. Pediatr Surg Int 15:248–250PubMedCrossRef
79.
Zurück zum Zitat Gamanagatti S, Garg R, Srivastava DP, Gupta A, Aggarwal S (2003) Spinal dysraphism with accessory thigh. Pediatr Radiol 33:809–810PubMedCrossRef Gamanagatti S, Garg R, Srivastava DP, Gupta A, Aggarwal S (2003) Spinal dysraphism with accessory thigh. Pediatr Radiol 33:809–810PubMedCrossRef
80.
Zurück zum Zitat Lende G, Wendemu W, Mørk S, Wester K (2007) A girl with spina bifida, an extra leg, and ectopic intestinal loops—a “foetus in foetu” or a whim of the neural crest? Acta Neurochir 149:1071–1075PubMedCrossRef Lende G, Wendemu W, Mørk S, Wester K (2007) A girl with spina bifida, an extra leg, and ectopic intestinal loops—a “foetus in foetu” or a whim of the neural crest? Acta Neurochir 149:1071–1075PubMedCrossRef
81.
Zurück zum Zitat Bayri Y, Tanrıkulu B, Ekşi MS, Dağçinar A (2014) Accessory lower limb associated with spina bifida: case report. Childs Nerv Syst 30:2123–2126PubMedCrossRef Bayri Y, Tanrıkulu B, Ekşi MS, Dağçinar A (2014) Accessory lower limb associated with spina bifida: case report. Childs Nerv Syst 30:2123–2126PubMedCrossRef
82.
Zurück zum Zitat Parks C, Mugamba J (2014) Accessory limb with myelomeningocele: a rare case challenging previously held beliefs. Childs Nerv Syst 30:2127–2128PubMedCrossRef Parks C, Mugamba J (2014) Accessory limb with myelomeningocele: a rare case challenging previously held beliefs. Childs Nerv Syst 30:2127–2128PubMedCrossRef
83.
Zurück zum Zitat Fulmer BB, Wilkins RH, Oakes WJ, Filston HC (1997) Midline dorsal appendages. Pediatr Neurosurg 27:242–245PubMedCrossRef Fulmer BB, Wilkins RH, Oakes WJ, Filston HC (1997) Midline dorsal appendages. Pediatr Neurosurg 27:242–245PubMedCrossRef
84.
85.
Zurück zum Zitat Ishikawa E, Matsumura A, Enomoto T, Tsurubuchi T, Nose T (2001) Ectopic fingerlike structure in the thoracic region. J Neurosurg 95(Spine 2):250–252PubMed Ishikawa E, Matsumura A, Enomoto T, Tsurubuchi T, Nose T (2001) Ectopic fingerlike structure in the thoracic region. J Neurosurg 95(Spine 2):250–252PubMed
86.
Zurück zum Zitat Kumar A, Kumar R (2013) Accessory digit and rudimentary male external genitalia associated with spinal dysraphism: a rare case of dysraphic appendages. Indian J Neurosurg 2:101–102CrossRef Kumar A, Kumar R (2013) Accessory digit and rudimentary male external genitalia associated with spinal dysraphism: a rare case of dysraphic appendages. Indian J Neurosurg 2:101–102CrossRef
87.
Zurück zum Zitat ter Haar B, Hamel B, Hendriks J, de Jager J (1982) Melnick-Needles syndrome: indication for an autosomal recessive form. Am J Med Genet 13:469–477PubMedCrossRef ter Haar B, Hamel B, Hendriks J, de Jager J (1982) Melnick-Needles syndrome: indication for an autosomal recessive form. Am J Med Genet 13:469–477PubMedCrossRef
88.
Zurück zum Zitat Kozlowski K, Campbell J, Anderson B, Erken EHW, Jequier S, Nelson M, Sliman N, Sprague P, Tamaela LA (1988) Metatropic dysplasia and its variants (analysis of 14 cases). Australas Radiol 32:325–337PubMedCrossRef Kozlowski K, Campbell J, Anderson B, Erken EHW, Jequier S, Nelson M, Sliman N, Sprague P, Tamaela LA (1988) Metatropic dysplasia and its variants (analysis of 14 cases). Australas Radiol 32:325–337PubMedCrossRef
89.
Zurück zum Zitat Teebi AS, Shaltout AA (1989) Craniofacial anomalies, abnormal hair, camptodactyly, and caudal appendage. Am J Med Genet 33:58–60PubMedCrossRef Teebi AS, Shaltout AA (1989) Craniofacial anomalies, abnormal hair, camptodactyly, and caudal appendage. Am J Med Genet 33:58–60PubMedCrossRef
90.
Zurück zum Zitat Lynch SA, Lee SG, Murday VA (1994) Caudal appendage, short terminal phalanges, deafness, cryptorchidism and mental retardation: a new syndrome? Clin Dysmorphol 3:340–346PubMedCrossRef Lynch SA, Lee SG, Murday VA (1994) Caudal appendage, short terminal phalanges, deafness, cryptorchidism and mental retardation: a new syndrome? Clin Dysmorphol 3:340–346PubMedCrossRef
91.
Zurück zum Zitat Guion-Almeida ML (1995) Apparent Malpuech syndrome: report on three Brazilian patients with additional signs. Am J Med Genet 58:13–17PubMedCrossRef Guion-Almeida ML (1995) Apparent Malpuech syndrome: report on three Brazilian patients with additional signs. Am J Med Genet 58:13–17PubMedCrossRef
92.
Zurück zum Zitat Crisponi G, Marras AR, Corrias A (1999) Two sibs with Malpuech syndrome. Am J Med Genet 86:294–299PubMedCrossRef Crisponi G, Marras AR, Corrias A (1999) Two sibs with Malpuech syndrome. Am J Med Genet 86:294–299PubMedCrossRef
93.
Zurück zum Zitat Galán-Gómez E, Carbonell-Pérez JM, Cardesa-García JJ, Val-Sánchez de León JM, Campo-Sampedro FM, Martínez-Frías ML, Frías JL (2004) A diagnostic conundrum: two siblings with features overlapping the Kabuki and Malpuech syndromes. A new MCA syndrome? Am J Med Genet 125A:306–309PubMedCrossRef Galán-Gómez E, Carbonell-Pérez JM, Cardesa-García JJ, Val-Sánchez de León JM, Campo-Sampedro FM, Martínez-Frías ML, Frías JL (2004) A diagnostic conundrum: two siblings with features overlapping the Kabuki and Malpuech syndromes. A new MCA syndrome? Am J Med Genet 125A:306–309PubMedCrossRef
94.
Zurück zum Zitat Turnbull C, Lees M, Chitty LS (2006) Prenatal sonographic diagnosis of Malpuech syndrome. Prenat Diagn 26:1121–1123PubMedCrossRef Turnbull C, Lees M, Chitty LS (2006) Prenatal sonographic diagnosis of Malpuech syndrome. Prenat Diagn 26:1121–1123PubMedCrossRef
95.
Zurück zum Zitat Leal GF, Silva EO, Duarte AR, Campos JF (2008) Blepharophimosis, blepharoptosis, defects of the anterior chamber of the eye, caudal appendage, radioulnar synostosis, hearing loss and umbilical anomalies in sibs: the 3MC syndrome? Am J Med Genet A 146A:1059–1062PubMedCrossRef Leal GF, Silva EO, Duarte AR, Campos JF (2008) Blepharophimosis, blepharoptosis, defects of the anterior chamber of the eye, caudal appendage, radioulnar synostosis, hearing loss and umbilical anomalies in sibs: the 3MC syndrome? Am J Med Genet A 146A:1059–1062PubMedCrossRef
96.
Zurück zum Zitat Sirmaci A, Walsh T, Akay H, Spiliopoulos M, Şakalar YB, Hasenefendioğlu-Bayrak A, Duman D, Farooq A, King M-C, Tekin M (2010) MASP1 mutations in patients with facial, umbilical, coccygeal, and auditory findings of Carnevale, Malpuech, OSA, and Michels syndromes. Am J Hum Genet 87:679–686PubMedPubMedCentralCrossRef Sirmaci A, Walsh T, Akay H, Spiliopoulos M, Şakalar YB, Hasenefendioğlu-Bayrak A, Duman D, Farooq A, King M-C, Tekin M (2010) MASP1 mutations in patients with facial, umbilical, coccygeal, and auditory findings of Carnevale, Malpuech, OSA, and Michels syndromes. Am J Hum Genet 87:679–686PubMedPubMedCentralCrossRef
97.
Zurück zum Zitat Chaouachi S, Ben Hamida E, Ennine I, Chaabouni M, Sfar R, Chaabouni H, Marrakchi Z (2010) Pallister-Killian syndrome with additional manifestations of cleft palate and sacral appendage. Tunis Med 88:614–616PubMed Chaouachi S, Ben Hamida E, Ennine I, Chaabouni M, Sfar R, Chaabouni H, Marrakchi Z (2010) Pallister-Killian syndrome with additional manifestations of cleft palate and sacral appendage. Tunis Med 88:614–616PubMed
98.
Zurück zum Zitat Petrides G, Bhat M, Holder S, Wakeling E (2008) Caudal appendage in focal dermal hypoplasia (Goltz syndrome). Clin Dysmorphol 17:129–131PubMedCrossRef Petrides G, Bhat M, Holder S, Wakeling E (2008) Caudal appendage in focal dermal hypoplasia (Goltz syndrome). Clin Dysmorphol 17:129–131PubMedCrossRef
99.
Zurück zum Zitat Cogulu O, Pariltay E, Koroglu OA, Aykut A, Ozyurek R, Levent E, Kultursay N, Ozkinay F (2013) Genome wide analysis in a discordant monozygotic twin with caudal appendage and multiple congenital anomalies. Genet Couns 24:85–91PubMed Cogulu O, Pariltay E, Koroglu OA, Aykut A, Ozyurek R, Levent E, Kultursay N, Ozkinay F (2013) Genome wide analysis in a discordant monozygotic twin with caudal appendage and multiple congenital anomalies. Genet Couns 24:85–91PubMed
100.
101.
Zurück zum Zitat Noack F, Reusche E, Gembruch U (2003) Prenatal diagnosis of ‘true tail’ with cartilage content? Fetal Diagn Ther 18:226–229PubMedCrossRef Noack F, Reusche E, Gembruch U (2003) Prenatal diagnosis of ‘true tail’ with cartilage content? Fetal Diagn Ther 18:226–229PubMedCrossRef
102.
Zurück zum Zitat Grangé G, Tantau J, Pannier E, Aubry M-C, Viot G, Fallet-Bianco C, Terrasse G, Cabrol D (2001) Prenatal diagnosis of fetal tail and postabortum anatomical description. Ultrasound Obstet Gynecol 18:531–533PubMedCrossRef Grangé G, Tantau J, Pannier E, Aubry M-C, Viot G, Fallet-Bianco C, Terrasse G, Cabrol D (2001) Prenatal diagnosis of fetal tail and postabortum anatomical description. Ultrasound Obstet Gynecol 18:531–533PubMedCrossRef
103.
Zurück zum Zitat Zimmer EZ, Bronshtein M (1996) Early sonographic findings suggestive of the human fetal tail. Prenat Diagn 16:360–362PubMedCrossRef Zimmer EZ, Bronshtein M (1996) Early sonographic findings suggestive of the human fetal tail. Prenat Diagn 16:360–362PubMedCrossRef
104.
Zurück zum Zitat Efrat Z, Perri T, Meizner I, Chen R, Ben-Rafael Z, Dekel A (2001) Early sonographic detection of a ‘human tail’: a case report. Ultrasound Obstet Gynecol 18:534–535PubMedCrossRef Efrat Z, Perri T, Meizner I, Chen R, Ben-Rafael Z, Dekel A (2001) Early sonographic detection of a ‘human tail’: a case report. Ultrasound Obstet Gynecol 18:534–535PubMedCrossRef
105.
Zurück zum Zitat Harirah H, Hsu C-D, Bahado-Singh R, Copel JA (2000) Human caudal appendage diagnosed prenatally with ultrasound. Obstet Gynecol 95:1038PubMed Harirah H, Hsu C-D, Bahado-Singh R, Copel JA (2000) Human caudal appendage diagnosed prenatally with ultrasound. Obstet Gynecol 95:1038PubMed
106.
Zurück zum Zitat Von Goethe JW (1977) Schriften zur Naturwissenschaft. Cotta, Stuttgart Von Goethe JW (1977) Schriften zur Naturwissenschaft. Cotta, Stuttgart
107.
Zurück zum Zitat Takada S, Stark KL, Shea MJ, Vassileva G, McMahon JA, McMahon AP (1994) Wnt-3a regulates somite and tailbud formation in the mouse embryo. Genes Dev 8:174–179PubMedCrossRef Takada S, Stark KL, Shea MJ, Vassileva G, McMahon JA, McMahon AP (1994) Wnt-3a regulates somite and tailbud formation in the mouse embryo. Genes Dev 8:174–179PubMedCrossRef
108.
Zurück zum Zitat Greco TL, Takada S, Newhouse MM, McMahon JA, McMahon AP, Camper SA (1996) Analysis of the vestigial tail mutation demonstrates that Wnt-3a gene dosage regulates mouse axial development. Genes Dev 10:313–324PubMedCrossRef Greco TL, Takada S, Newhouse MM, McMahon JA, McMahon AP, Camper SA (1996) Analysis of the vestigial tail mutation demonstrates that Wnt-3a gene dosage regulates mouse axial development. Genes Dev 10:313–324PubMedCrossRef
109.
Zurück zum Zitat Gould GM, Pyle WL (1896) Anomalies and curiosities of medicine. Philadelphia: Saunders 1896:277–279 Gould GM, Pyle WL (1896) Anomalies and curiosities of medicine. Philadelphia: Saunders 1896:277–279
Metadaten
Titel
Proposed caudal appendage classification system; spinal cord tethering associated with sacrococcygeal eversion
verfasst von
C. Corbett Wilkinson
Arianne J Boylan
Publikationsdatum
06.08.2016
Verlag
Springer Berlin Heidelberg
Erschienen in
Child's Nervous System / Ausgabe 1/2017
Print ISSN: 0256-7040
Elektronische ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-016-3208-x

Weitere Artikel der Ausgabe 1/2017

Child's Nervous System 1/2017 Zur Ausgabe

Mehr Frauen im OP – weniger postoperative Komplikationen

21.05.2024 Allgemeine Chirurgie Nachrichten

Ein Frauenanteil von mindestens einem Drittel im ärztlichen Op.-Team war in einer großen retrospektiven Studie aus Kanada mit einer signifikanten Reduktion der postoperativen Morbidität assoziiert.

„Übersichtlicher Wegweiser“: Lauterbachs umstrittener Klinik-Atlas ist online

17.05.2024 Klinik aktuell Nachrichten

Sie sei „ethisch geboten“, meint Gesundheitsminister Karl Lauterbach: mehr Transparenz über die Qualität von Klinikbehandlungen. Um sie abzubilden, lässt er gegen den Widerstand vieler Länder einen virtuellen Klinik-Atlas freischalten.

Was nützt die Kraniektomie bei schwerer tiefer Hirnblutung?

17.05.2024 Hirnblutung Nachrichten

Eine Studie zum Nutzen der druckentlastenden Kraniektomie nach schwerer tiefer supratentorieller Hirnblutung deutet einen Nutzen der Operation an. Für überlebende Patienten ist das dennoch nur eine bedingt gute Nachricht.

Klinikreform soll zehntausende Menschenleben retten

15.05.2024 Klinik aktuell Nachrichten

Gesundheitsminister Lauterbach hat die vom Bundeskabinett beschlossene Klinikreform verteidigt. Kritik an den Plänen kommt vom Marburger Bund. Und in den Ländern wird über den Gang zum Vermittlungsausschuss spekuliert.

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

Karpaltunnelsyndrom BDC Leitlinien Webinare
CME: 2 Punkte

Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

Radiusfraktur BDC Leitlinien Webinare
CME: 2 Punkte

Das Webinar beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

Appendizitis BDC Leitlinien Webinare
CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.