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European Archives of Oto-Rhino-Laryngology
Erschienen in: European Archives of Oto-Rhino-Laryngology 5/2015

01.05.2015 | Head and Neck

Prognostic factors of quality of life after transoral laser microsurgery for laryngeal cancer

verfasst von: Isabel Vilaseca, Manuel Bernal-Sprekelsen, Ruth Him, Alexandra Mandry, Eduardo Lehrer, José Luis Blanch

Erschienen in: European Archives of Oto-Rhino-Laryngology | Ausgabe 5/2015

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Abstract

We aimed to evaluate factors influencing quality of life (QOL) after transoral laser microsurgery (TLM) of laryngeal cancer. Four hundred and one consecutive disease-free patients were evaluated 1 year after treatment using the University of Washington-QOL v4, the SF-12 (short form of SF-36), and a questionnaire about self-rated health status. The importance of age, gender, tumor location, tumor size, tumor stage, neck dissection and adjuvant treatment were evaluated. One year after TLM patients had a good QOL, with only 6 % of patients reporting a worsening in their health status. Radiation therapy (p = 0.000) and neck dissection (p = 0.000) were negative factors for disease-specific QOL, whereas age ≥70 (p = 0.01) was a positive independent factor for mental score of SF-12. Speech was negatively influenced by tumor size (p = 0.001) as was swallowing by age (p = 0.001) and postoperative radiation (p = 0.000). Patients treated with TLM present a good QOL 1 year after surgery. Radiation and neck dissection negatively impact QOL. Elderly patients cope better with their disabilities.
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Metadaten
Titel
Prognostic factors of quality of life after transoral laser microsurgery for laryngeal cancer
verfasst von
Isabel Vilaseca
Manuel Bernal-Sprekelsen
Ruth Him
Alexandra Mandry
Eduardo Lehrer
José Luis Blanch
Publikationsdatum
01.05.2015
Verlag
Springer Berlin Heidelberg
Erschienen in
European Archives of Oto-Rhino-Laryngology / Ausgabe 5/2015
Print ISSN: 0937-4477
Elektronische ISSN: 1434-4726
DOI
https://doi.org/10.1007/s00405-014-3030-6

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