Erschienen in:
01.08.2008 | Case Report
Histological evaluation of liver in two rheumatoid arthritis patients with chronic hepatitis B and C treated with TNF-alpha blockade: case reports
verfasst von:
Primal P. Kaur, Virginia C. Chan, Steven N. Berney
Erschienen in:
Clinical Rheumatology
|
Ausgabe 8/2008
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Abstract
Tumor necrosis factor (TNF)-alpha antagonists successfully modulate the pathogenesis of rheumatoid arthritis (RA). However, little is known about the effect of TNF-alpha blockade on the histology of chronic viral hepatitis. We describe the cases of two patients with RA, one with concurrent chronic hepatitis B virus and the other with hepatitis C virus infection who, as part of their evaluation, underwent liver biopsies while undergoing treatment with a TNF-alpha antagonist.