Introduction
Methods
Patient population
CTA data acquisition
CTA data analysis
ICA and revascularization
Statistical analysis
Results
Study population
Age (years) | 56 ± 12 |
Men/women | 296/341 |
Diabetes | 19 % |
Hypercholesterolemiaa
| 34 % |
Hypertensionb
| 43 % |
Family history of CADc
| 46 % |
Smoking | 20 % |
Obesityd
| 21 % |
Reason of referral for CTA | |
Typical chest pain | 21 % |
Atypical chest pain | 46 % |
Non-anginal chest pain | 33 % |
CTA results
ICA
Variable | Univariate | Multivariate | ||
---|---|---|---|---|
OR (95 % CI) |
p-value | OR (95 % CI) |
p-value | |
ICA | ||||
Age | 1.05 (1.03–1.06) | <0.001 | 1.02 (0.99–1.04) | 0.112 |
Gender | 1.92 (1.35–2.73) | <0.001 | 1.81 (1.13–2.91) | 0.014 |
Diabetes | 1.35 (0.87–2.08) | 0.182 | – | – |
Hypercholesterolemia | 2.19 (1.53–3.14) | <0.001 | 1.42 (0.87–2.30) | 0.162 |
Hypertension | 2.09 (1.47–2.98) | <0.001 | 1.51 (0.93–2.46) | 0.098 |
Family history of CAD | 0.83 (0.58–1.17) | 0.282 | – | – |
Smoking | 2.70 (1.78–4.09) | <0.001 | 2.35 (1.33–4.14) | 0.003 |
Obesity | 1.08 (0.69–1.67) | 0.749 | – | – |
Significant CAD on CTAa
| 22.62 (14.41–35.51) | <0.001 | 18.60 (11.46–30.19) | <0.001 |
Significant three-vessel or left main disease on CTAa
| 18.23 (6.32–52.59) | <0.001 | 15.67 (4.59–53.43) | <0.001 |
Revascularization | ||||
Age | 1.05 (1.03–1.07) | <0.001 | 1.02 (0.99–1.06) | 0.134 |
Gender | 2.80 (1.73–4.53) | <0.001 | 2.90 (1.54–5.46) | 0.001 |
Diabetes | 2.08 (1.24–3.49) | 0.005 | 2.10 (1.00–4.43) | 0.050 |
Hypercholesterolemia | 2.31 (1.46–3.66) | <0.001 | 1.45 (0.78–2.69) | 0.243 |
Hypertension | 1.92 (1.22–3.04) | 0.005 | – | – |
Family history of CAD | 0.67 (0.42–1.07) | 0.095 | – | – |
Smoking | 3.43 (2.11–5.58) | <0.001 | 3.24 (1.60–6.57) | 0.001 |
Obesity | 1.09 (0.62–1.92) | 0.773 | – | – |
Significant CAD on CTAa
| 338.06 (46.53–2,456.30) | <0.001 | 282.61 (38.21–2,090.31) | <0.001 |
Significant three-vessel or left main disease on CTAa
| 15.62 (7.27–33.54) | <0.001 | 12.31 (5.52–28.91) | <0.001 |