Introduction
Methods
Study design and participants
Data collection
Statistical analysis
Results
Responders (n = 169) | PRESENT-cohorta (n = 432) | |
---|---|---|
Gender | ||
Male (%) | 104 (62) | 255 (56) |
Age at inclusion (years) | ||
Median (range) | 66 (33–92) | 67 (28–90) |
Primary cancer site (%) | ||
Prostate | 54 (35) | 127 (29) |
Breast | 40 (26) | 97 (23) |
Lung | 28 (18) | 97 (23) |
Other | 34 (22) | 111 (25) |
Non-bone metastases (%) | ||
Visceral | 64 (38) | 170 (39) |
Brain | 2 (1) | 6 (1) |
Radiation treatment | ||
8 Gy; 1 × 8 Gy | 72 (43) | 290 (67) |
30 Gy; 10 × 3 Gy | 46 (27) | 72 (17) |
Other | 51 (39) | 70 (16) |
Age at time of start lockdown (years) | ||
Median (range) | 68 (38–92) | N/A |
Time between lockdown date and questionnaire (median) | ||
Before lockdown-1 | 3 months | N/A |
Before lockdown-2 | 8 months | N/A |
Living situation | ||
Alone | 25 (15) | N/A |
With Partner | 132 (78) | N/A |
With Children | 16 (10) | N/A |
Other | 6 (4) | N/A |
Number of patients (N = 169) | Percentage | |
---|---|---|
Are / were you infected by the COVID-19 virus? | ||
Yes, confirmed by nasopharyngeal swab | 0 | 0.0 |
Possibly, I have or had fever and symptoms, but was not tested | 11 | 6.5 |
No, I was tested negative | 3 | 1.8 |
No, I had/ have no symptoms and I was not tested | 148 | 87.6 |
Are you concerned about being infected by the COVID-19 virus? | ||
Not at all | 17 | 10.1 |
A little bit | 93 | 55.0 |
Quite a bit | 45 | 26.6 |
Very much | 6 | 3.6 |
Are you worried about your health care as a result of COVID-19? | ||
I worry more about my health care / treatment | 83 | 49.1 |
I worry less about my health care / treatment | 15 | 8.9 |
no difference since the start of COVID-19 | 64 | 37.9 |
Global patient impression of change regarding your global health status since start of COVID-19 lockdown | ||
Improved global health status | 12 | 7.1 |
No change in global health status | 112 | 66.3 |
Worsened global health status | 43 | 25.4 |
Were there any changes in your health care as a result of COVID-19? | ||
No changes | 52 | 30.8 |
Measures were taken but appointments were kept face to face | 11 | 6.5 |
Hospital appointments were converted to online appointments | 62 | 36.7 |
Hospital appointments were cancelled | 25 | 14.8 |
Hospital appointments were postponed | 17 | 10.1 |
My treatment was altered | 15 | 8.9 |
My treatment was postponed | 10 | 5.9 |
My treatment was cancelled | 9 | 5.3 |
Second opinion was postponed | 3 | 1.8 |
Second opinion was cancelled | 1 | 0.6 |
Did the threshold to contact your general practitioner or oncologist change because of the COVID-19 situation? | ||
Yes, I contact my physician less easily | 26 | 15.4 |
Yes, I contact my physician more easily | 3 | 1.8 |
No, nothing changed in how easily I contact my physician | 133 | 78.7 |
Did you leave your house the last few days? | ||
I don't go outside at all anymore due to COVID-19 | 28 | 16.6 |
I go outside rarely, for instance to go for a short walk | 79 | 46.7 |
I go outside as much as I can taking social distancing into account | 31 | 18.3 |
I go outside just as much as before COVID-19 | 10 | 5.9 |
Other | 13 | 7.7 |
How were your social contacts (physical and virtual) the last few days? | ||
I have no or barely any contact with family and friends | 23 | 13.6 |
Contact with my family and friends decreased | 83 | 49.1 |
Contact with my family and friends stayed the same | 37 | 21.9 |
I have more contact with my family and friends | 18 | 11.1 |
Do you experience stress or anxiety due to the coronavirus? | ||
I am stressed or anxious due to COVID-19 | 47 | 27.8 |
I am not at all stressed or anxious due to COVID-19 | 49 | 29.1 |
There's no difference in my stress level due to COVID-19 | 65 | 38.5 |
Quality of life
Scale | Timepoint | n | Mean | SD | t | P |
---|---|---|---|---|---|---|
Worst pain 3 days (BPI) | During Lockdown | 177 | 2.85 | 2.58 | 2.63 | 0.009 |
Before Lockdown-1 | 177 | 3.36 | 2.82 | |||
During Lockdown | 154 | 2.74 | 2.53 | 0.58 | 0.566 | |
Before Lockdown-2 | 154 | 2.86 | 2.73 | |||
General Quality of Life (EORTC-C15-PAL) | During Lockdown | 174 | 68.68 | 19.32 | 2.75 | 0.007 |
Before Lockdown-1 | 174 | 72.41 | 18.77 | |||
During Lockdown | 152 | 69.3 | 19.19 | 0.99 | 0.326 | |
Before Lockdown-2 | 152 | 71.05 | 20.37 | |||
Emotional functioning scale (EORTC-C15-PAL) | During Lockdown | 177 | 79.24 | 20.73 | 2.92 | 0.004 |
Before Lockdown-1 | 177 | 83.57 | 18.55 | |||
During Lockdown | 154 | 80.36 | 19.74 | 2.62 | 0.01 | |
Before Lockdown-2 | 154 | 84.80 | 18.20 |
Discussion
Before lockdown-2 N (%) | Before lockdown-1 N (%) | During lockdown N (%) | |
---|---|---|---|
Stress | N = 155 | N = 178 | N = 200 |
Not at all | 84 (54) | 98 (55) | 85 (43) |
A little bit | 58 (37) | 64 (36) | 86 (43) |
Quite a bit | 11 (7) | 13 (7) | 26 (13) |
Very much | 2 (1) | 3 (2) | 3 (2) |
Isolationfrom close friends and relatives | N = 153 | N = 176 | N = 197 |
Not at all | 128 (84) | 144 (82) | 66 (34) |
A little bit | 19 (12) | 25 (14) | 78 (40) |
Quite a bit | 4 (3) | 6 (3) | 39 (20) |
Very much | 2 (1) | 1 (1) | 14 (7) |
Dependence | N = 154 | N = 176 | N = 198 |
Not at all | 79 (51) | 81 (46) | 75 (38) |
A little bit | 52 (34) | 58 (33) | 82 (41) |
Quite a bit | 16 (10) | 27 (15) | 32 (16) |
Very much | 7 (5) | 10 (6) | 9 (5) |
Worry about health | N = 154 | N = 176 | N = 198 |
Not at all | 30 (20) | 42 (24) | 29 (15) |
A little bit | 79 (51) | 66 (38) | 99 (50) |
Quite a bit | 30 (20) | 51 (29) | 55 (28) |
Very much | 15 (10) | 17 (10) | 15 (8) |