Skip to main content
Erschienen in: Journal of Urban Health 1/2009

01.01.2009

HIV Prevalence Rates among Injection Drug Users in 96 Large US Metropolitan Areas, 1992–2002

verfasst von: Barbara Tempalski, Spencer Lieb, Charles M. Cleland, Hannah Cooper, Joanne E. Brady, Samuel R. Friedman

Erschienen in: Journal of Urban Health | Ausgabe 1/2009

Einloggen, um Zugang zu erhalten

Abstract

This research presents estimates of HIV prevalence rates among injection drug users (IDUs) in large US metropolitan statistical areas (MSAs) during 1992–2002. Trend data on HIV prevalence rates in geographic areas over time are important for research on determinants of changes in HIV among IDUs. Such data also provide a foundation for the design and implementation of structural interventions for preventing the spread of HIV among IDUs. Our estimates of HIV prevalence rates among IDUs in 96 US MSAs during 1992–2002 are derived from four independent sets of data: (1) research-based HIV prevalence rate estimates; (2) Centers for Disease Control and Prevention Voluntary HIV Counseling and Testing data (CDC CTS); (3) data on the number of people living with AIDS compiled by the CDC (PLWAs); and (4) estimates of HIV prevalence in the US. From these, we calculated two independent sets of estimates: (1) calculating CTS-based Method (CBM) using regression adjustments to CDC CTS; and (2) calculating the PLWA-based Method (PBM) by taking the ratio of the number of injectors living with HIV to the numbers of injectors living in the MSA. We take the mean of CBM and PBM to calculate over all HIV prevalence rates for 1992–2002. We evaluated trends in IDU HIV prevalence rates by calculating estimated annual percentage changes (EAPCs) for each MSA. During 1992–2002, HIV prevalence rates declined in 85 (88.5%) of the 96 MSAs, with EAPCs ranging from −12.9% to −2.1% (mean EAPC = −6.5%; p < 0.01). Across the 96 MSAs, collectively, the annual mean HIV prevalence rate declined from 11.2% in 1992 to 6.2 in 2002 (EAPC, −6.4%; p < 0.01). Similarly, the median HIV prevalence rate declined from 8.1% to 4.4% (EAPC, −6.5%; p < 0.01). The maximum HIV prevalence rate across the 11 years declined from 43.5% to 22.8% (EAPC, −6.7%; p < 0.01). Declining HIV prevalence rates may reflect high continuing mortality among infected IDUs, as well as primary HIV prevention for non-infected IDUs and self-protection efforts by them. These results warrant further research into the population dynamics of disease progression, access to health services, and the effects of HIV prevention interventions for IDUs.
Anhänge
Nur mit Berechtigung zugänglich
Fußnoten
1
e.g., number of IDUS tested in 1992 N = 673; number tested in 1997 N = 88.
 
2
Akron, OH; Charleston, SC; Gary, IN; Greenville, SC; Kansas City, KS; Minneapolis–St. Paul, MN-WI; Syracuse, NY; Ventura, CA; Youngstown, PA.
 
3
Birmingham, AL; Little Rock, AR; Norfolk, VA; San Juan, PR; Wichita, KS.
 
4
Albany-Schenectady, NY; Ann Arbor, MI; Atlanta, GA; Buffalo-Niagara Falls, NY; Nassau–Suffolk, NY; Providence–Fall River–Warwick, RI–MA; Rochester, NY.
 
Literatur
1.
Zurück zum Zitat Brown BS, Beschner GM. Handbook on Risk of AIDS: Injection Drug Users and Sexual Partners. Westport, CT: Greenwood; 1993. Brown BS, Beschner GM. Handbook on Risk of AIDS: Injection Drug Users and Sexual Partners. Westport, CT: Greenwood; 1993.
2.
Zurück zum Zitat Friedman SR, Jose B, Deren S, Des Jarlais DC, Neaigus A. Risk factors for HIV seroconversion among out-of-treatment drug injectors in high- and low-seroprevalence cities. Am J Epidemiol. 1995;142:864–874.PubMed Friedman SR, Jose B, Deren S, Des Jarlais DC, Neaigus A. Risk factors for HIV seroconversion among out-of-treatment drug injectors in high- and low-seroprevalence cities. Am J Epidemiol. 1995;142:864–874.PubMed
4.
Zurück zum Zitat Kral AH, Bluthenthal RN, Booth RE, Watters JK. HIV seroprevalence among street-recruited injection drug and crack cocaine users in 16 US municipalities. Am J Public Health. 1998;88:108–113.PubMedCrossRef Kral AH, Bluthenthal RN, Booth RE, Watters JK. HIV seroprevalence among street-recruited injection drug and crack cocaine users in 16 US municipalities. Am J Public Health. 1998;88:108–113.PubMedCrossRef
5.
Zurück zum Zitat Malliori M, Zunzunegui MV, Rodriguez-Arenas A, Goldberg D. Drug injecting and HIV-1 infection: major findings from a multi-city study. In: Stimson GV, Des Jarlais DC, Ball A, eds. Drug Injecting and HIV Infection: Global Dimensions and Local Responses. London: Taylor and Francis; 1998. Malliori M, Zunzunegui MV, Rodriguez-Arenas A, Goldberg D. Drug injecting and HIV-1 infection: major findings from a multi-city study. In: Stimson GV, Des Jarlais DC, Ball A, eds. Drug Injecting and HIV Infection: Global Dimensions and Local Responses. London: Taylor and Francis; 1998.
6.
Zurück zum Zitat Stimson GV, Des Jarlais DC, Ball A. Drug Injecting and HIV Infection: Global Dimensions and Local Responses. London: UCL; 1998. Stimson GV, Des Jarlais DC, Ball A. Drug Injecting and HIV Infection: Global Dimensions and Local Responses. London: UCL; 1998.
9.
Zurück zum Zitat Kral AH, Page-Shafer K, Kellogg T, et al. Persistent HIV incidence among injection drug users in San Francisco during the 1990s: results of five studies. J Acquir Immune Defic Syndr. 2004;37:1667–1669. doi:10.1097/00126334-200412150-00025.PubMed Kral AH, Page-Shafer K, Kellogg T, et al. Persistent HIV incidence among injection drug users in San Francisco during the 1990s: results of five studies. J Acquir Immune Defic Syndr. 2004;37:1667–1669. doi:10.​1097/​00126334-200412150-00025.PubMed
13.
Zurück zum Zitat Novick DM, Trigg HL, Des Jarlais DC, Friedman SR, Vlahov D, Kreek MJ. Cocaine injection and ethnicity in parenteral drug users during the early years of the human immunodeficiency virus (HIV) epidemic in New York City. J Med Virol. 1989;29:181–185. doi:10.1002/jmv.1890290307.PubMedCrossRef Novick DM, Trigg HL, Des Jarlais DC, Friedman SR, Vlahov D, Kreek MJ. Cocaine injection and ethnicity in parenteral drug users during the early years of the human immunodeficiency virus (HIV) epidemic in New York City. J Med Virol. 1989;29:181–185. doi:10.​1002/​jmv.​1890290307.PubMedCrossRef
17.
Zurück zum Zitat Joint Assessment of HIV/AIDS Prevention. Treatment and Care in China. State Council HIV/AIDS Working Committee Office and UN Theme Group on HIV/AIDS in China. 2004. Joint Assessment of HIV/AIDS Prevention. Treatment and Care in China. State Council HIV/AIDS Working Committee Office and UN Theme Group on HIV/AIDS in China. 2004.
21.
Zurück zum Zitat Holmberg SD. The estimated prevalence and incidence of HIV in 96 large US metropolitan areas. Am J Public Health. 1996;86:642–654.PubMedCrossRef Holmberg SD. The estimated prevalence and incidence of HIV in 96 large US metropolitan areas. Am J Public Health. 1996;86:642–654.PubMedCrossRef
24.
Zurück zum Zitat Centers for Disease Control and Prevention. HIV/AIDS Surveillance Report, 2004. Atlanta: US Department of Health and Human Services. Centers Dis Contr Prev 2005;16:1–46. Centers for Disease Control and Prevention. HIV/AIDS Surveillance Report, 2004. Atlanta: US Department of Health and Human Services. Centers Dis Contr Prev 2005;16:1–46.
26.
Zurück zum Zitat Centers for Disease Control and Prevention. Trends in HIV/AIDS diagnoses among men who have sex with men—33 states, 2001–2006. Morb Mort Wkly Rep. 2008;57:681–716. Centers for Disease Control and Prevention. Trends in HIV/AIDS diagnoses among men who have sex with men—33 states, 2001–2006. Morb Mort Wkly Rep. 2008;57:681–716.
27.
Zurück zum Zitat Lieb S, Friedman SR, Zeni MB, et al. An HIV prevalence-based model for estimating urban risk-populations of injection drug users and men who have sex with men. J Urban Health. 2004;81:401–415. doi:10.1093/jurban/jth126.PubMed Lieb S, Friedman SR, Zeni MB, et al. An HIV prevalence-based model for estimating urban risk-populations of injection drug users and men who have sex with men. J Urban Health. 2004;81:401–415. doi:10.​1093/​jurban/​jth126.PubMed
28.
Zurück zum Zitat Lieb S, Trepka MJ, Thompson DR, et al. Men who have sex with men: estimated population sizes and mortality rates, by race/ethnicity, Miami–Dade County, Florida. J Acquir Immune Defic Syndr. 2007;46:485–490.PubMed Lieb S, Trepka MJ, Thompson DR, et al. Men who have sex with men: estimated population sizes and mortality rates, by race/ethnicity, Miami–Dade County, Florida. J Acquir Immune Defic Syndr. 2007;46:485–490.PubMed
29.
Zurück zum Zitat Office of Management and Budget. Standards for defining metropolitan and micropolitan statistical areas. Fed Regist. 2000;65:8228–82238. Office of Management and Budget. Standards for defining metropolitan and micropolitan statistical areas. Fed Regist. 2000;65:8228–82238.
30.
Zurück zum Zitat Brady JE, Friedman SR, Cooper HL, Flom PL, Tempalski B, Gostnell K. Estimating the prevalence of injection drug users in the US and in large US metropolitan areas from 1992 to 2002. J Urban Health. 2008;85:323–351. doi:10.1007/s11524-007-9248-5.PubMedCrossRef Brady JE, Friedman SR, Cooper HL, Flom PL, Tempalski B, Gostnell K. Estimating the prevalence of injection drug users in the US and in large US metropolitan areas from 1992 to 2002. J Urban Health. 2008;85:323–351. doi:10.​1007/​s11524-007-9248-5.PubMedCrossRef
31.
Zurück zum Zitat Centers for Disease Control and Prevention. HIV/AIDS Surveillance Supplemental Report: AHIV/AIDS in Urban and Nonurban Area of the United States. Atlanta: US Department of Health and Human Services. Centers Dis Contr Prev 2000;6:1–15. Centers for Disease Control and Prevention. HIV/AIDS Surveillance Supplemental Report: AHIV/AIDS in Urban and Nonurban Area of the United States. Atlanta: US Department of Health and Human Services. Centers Dis Contr Prev 2000;6:1–15.
32.
Zurück zum Zitat Cronk CE, Sarvela PD. Alcohol, tobacco, and other drug use among rural/small town and urban youth: A secondary analysis of the monitoring the future data set. Am J Public Health. 1997;80:760–764.CrossRef Cronk CE, Sarvela PD. Alcohol, tobacco, and other drug use among rural/small town and urban youth: A secondary analysis of the monitoring the future data set. Am J Public Health. 1997;80:760–764.CrossRef
34.
Zurück zum Zitat Hutchison L, Blakely C. Substance Abuse Trends in Rural Areas. Rural Healthy People 2010: A companion document to Healthy People 2010. Volume 1. College Station, TX: The Texas AM University System Health Science Center, School of Rural Public Health, Southwest Rural Health Research Center; 2003. Hutchison L, Blakely C. Substance Abuse Trends in Rural Areas. Rural Healthy People 2010: A companion document to Healthy People 2010. Volume 1. College Station, TX: The Texas AM University System Health Science Center, School of Rural Public Health, Southwest Rural Health Research Center; 2003.
35.
Zurück zum Zitat Kline A, Mammo A, Culleton R, et al. Trends in injection drug use among persons entering addiction treatment—New Jersey, 1992–1999. Morb Mort Wkly Rep. 2001;50:378–381. Kline A, Mammo A, Culleton R, et al. Trends in injection drug use among persons entering addiction treatment—New Jersey, 1992–1999. Morb Mort Wkly Rep. 2001;50:378–381.
36.
Zurück zum Zitat Substance Abuse and Mental Health Services Administration, Office of Applied Studies. The NSDUH Report: Demographic and Geographic Variations in Injection Drug Use. Rockville, MD; 2007. Substance Abuse and Mental Health Services Administration, Office of Applied Studies. The NSDUH Report: Demographic and Geographic Variations in Injection Drug Use. Rockville, MD; 2007.
37.
Zurück zum Zitat Steel E, Fleming PL, Needle R. The HIV rates of injection drug users in less-populated areas. Am J Public Health. 1993;83:286–287.PubMedCrossRef Steel E, Fleming PL, Needle R. The HIV rates of injection drug users in less-populated areas. Am J Public Health. 1993;83:286–287.PubMedCrossRef
38.
Zurück zum Zitat Cleveland WS, Grosse E, Shyu WM. Local regression models. Chapter 8 of Statistical Models in Social Sciences. Chambers JM, Hastie TJ, eds. Brooks/Cole; 1992. Cleveland WS, Grosse E, Shyu WM. Local regression models. Chapter 8 of Statistical Models in Social Sciences. Chambers JM, Hastie TJ, eds. Brooks/Cole; 1992.
39.
Zurück zum Zitat Friedman SR, Perlis T, Des Jarlais DC. Laws prohibiting over-the-counter syringe sales to injection drug users: relations to population density, HIV prevalence, and HIV incidence. Am J Public Health. 2001;91:791–793.PubMedCrossRef Friedman SR, Perlis T, Des Jarlais DC. Laws prohibiting over-the-counter syringe sales to injection drug users: relations to population density, HIV prevalence, and HIV incidence. Am J Public Health. 2001;91:791–793.PubMedCrossRef
41.
Zurück zum Zitat Friedman SR, Cooper HL, Tempalski B, et al. Relationships of deterrence and law enforcement to drug-related harms among drug injectors in US metropolitan areas. AIDS. 2006;20:93–99.PubMed Friedman SR, Cooper HL, Tempalski B, et al. Relationships of deterrence and law enforcement to drug-related harms among drug injectors in US metropolitan areas. AIDS. 2006;20:93–99.PubMed
42.
Zurück zum Zitat Bluthenthal RN, Kral AH, Erringer EA, Edlin BR. Drug paraphernalia laws and injection-related infectious disease risk among drug injectors. Drug Issues. 1999a;22:1–16. Bluthenthal RN, Kral AH, Erringer EA, Edlin BR. Drug paraphernalia laws and injection-related infectious disease risk among drug injectors. Drug Issues. 1999a;22:1–16.
43.
Zurück zum Zitat Friedman SR, Perlis T, Lynch J, Des Jarlais DC. Economic inequality, poverty, and laws against syringe access as predictors of metropolitan area rates of drug injection and HIV infection. Proceedings of the Global Research Network Meeting, Durban, South Africa. July 2000. Friedman SR, Perlis T, Lynch J, Des Jarlais DC. Economic inequality, poverty, and laws against syringe access as predictors of metropolitan area rates of drug injection and HIV infection. Proceedings of the Global Research Network Meeting, Durban, South Africa. July 2000.
49.
Zurück zum Zitat Federal Bureau of Investigation. US Uniform Crime Reporting Program Data: County-Level Detailed Arrest and Offense Data. 1992–2002. Federal Bureau of Investigation. US Uniform Crime Reporting Program Data: County-Level Detailed Arrest and Offense Data. 1992–2002.
50.
Zurück zum Zitat United States Census Bureau. United States Census Annual Surveys of Government Finances. 1992. United States Census Bureau. United States Census Annual Surveys of Government Finances. 1992.
51.
Zurück zum Zitat United States Census Bureau. United States Census Annual Surveys of Government Finances. 1997. United States Census Bureau. United States Census Annual Surveys of Government Finances. 1997.
52.
Zurück zum Zitat United States Census Bureau. United States Census Annual Surveys of Government Finances. 2002. United States Census Bureau. United States Census Annual Surveys of Government Finances. 2002.
54.
Zurück zum Zitat Kaplan GA, Pamuk ER, Lynch JW, Cohen RD, Balfour JL. Inequality in income and mortality in the United States: analysis of mortality and potential pathways. BMJ. 1996;312:999–1003.PubMed Kaplan GA, Pamuk ER, Lynch JW, Cohen RD, Balfour JL. Inequality in income and mortality in the United States: analysis of mortality and potential pathways. BMJ. 1996;312:999–1003.PubMed
55.
Zurück zum Zitat Diez-Roux AV, Nieto FJ, Muntaner C, et al. Neighborhood environments and coronary heart disease: a multilevel analysis. Am J Epidemiol. 1997;146:48–63.PubMed Diez-Roux AV, Nieto FJ, Muntaner C, et al. Neighborhood environments and coronary heart disease: a multilevel analysis. Am J Epidemiol. 1997;146:48–63.PubMed
56.
Zurück zum Zitat Diez-Roux AV, Nieto FJ, Caulfield L, Tyroler HA, Watson RL, Szklo M. Neighborhood differences in diet: the Atherosclerosis in Communities (ARIC) Study. J Epidemiol Community Health. 1999;53:55–63.PubMedCrossRef Diez-Roux AV, Nieto FJ, Caulfield L, Tyroler HA, Watson RL, Szklo M. Neighborhood differences in diet: the Atherosclerosis in Communities (ARIC) Study. J Epidemiol Community Health. 1999;53:55–63.PubMedCrossRef
57.
58.
Zurück zum Zitat United States Census Bureau. Housing and Household Economic Statistics Division. Poverty Index; 2000. United States Census Bureau. Housing and Household Economic Statistics Division. Poverty Index; 2000.
59.
Zurück zum Zitat Des Jarlais DC, Hagan H, Friedman SR, Ward TP. HIV among injecting drug users: epidemiology and emerging public health perspectives. In: Merigan TC Jr, Bartlett JG, Bolognesi D, eds. Textbook of AIDS Medicine, 2nd edn. Baltimore: Williams Wilkins; 1999. Des Jarlais DC, Hagan H, Friedman SR, Ward TP. HIV among injecting drug users: epidemiology and emerging public health perspectives. In: Merigan TC Jr, Bartlett JG, Bolognesi D, eds. Textbook of AIDS Medicine, 2nd edn. Baltimore: Williams Wilkins; 1999.
60.
Zurück zum Zitat Burris S, Vernick J, Ditzler A, Strathdee S. The legality of selling or giving syringes to injection drug users. In: Jones TS, Coffin PO, eds. Preventing blood-borne infections through pharmacy syringe sales and safe community syringe disposal. J Am Pharm Assoc 2002;42(Suppl. 2):S13–S17. Burris S, Vernick J, Ditzler A, Strathdee S. The legality of selling or giving syringes to injection drug users. In: Jones TS, Coffin PO, eds. Preventing blood-borne infections through pharmacy syringe sales and safe community syringe disposal. J Am Pharm Assoc 2002;42(Suppl. 2):S13–S17.
61.
Zurück zum Zitat SAS Institute. SAS/STAT® 9.1 User’s Guide. Cary, NC: SAS Institute; 2004. SAS Institute. SAS/STAT® 9.1 User’s Guide. Cary, NC: SAS Institute; 2004.
62.
Zurück zum Zitat R Development Core Team. (2008). R: A language and environment for statistical computing. Foundation for Statistical Computing, Vienna, Austria. ISBN 3-900051-07-0, URL http://www.R-project.org. R Development Core Team. (2008). R: A language and environment for statistical computing. Foundation for Statistical Computing, Vienna, Austria. ISBN 3-900051-07-0, URL http://​www.​R-project.​org.
66.
Zurück zum Zitat Morris JD, Golub ET, Mehta SH, Jacobson L, Gange SJ. Injection drug use and patterns of highly active antiretroviral therapy use: an analysis of ALIVE, WIHS, and MACS cohorts. AIDS Res Ther. 2007;4:1–8. doi:10.1186/1742-6405-4-12.CrossRef Morris JD, Golub ET, Mehta SH, Jacobson L, Gange SJ. Injection drug use and patterns of highly active antiretroviral therapy use: an analysis of ALIVE, WIHS, and MACS cohorts. AIDS Res Ther. 2007;4:1–8. doi:10.​1186/​1742-6405-4-12.CrossRef
67.
Zurück zum Zitat Des Jarlais DC, Perlis TE, Friedman SR, et al. Declining seroprevalence in a very large HIV epidemic: Injecting drug users in New York City, 1991 to 1996. Am J Public Health. 1998;88:1801–1806.PubMedCrossRef Des Jarlais DC, Perlis TE, Friedman SR, et al. Declining seroprevalence in a very large HIV epidemic: Injecting drug users in New York City, 1991 to 1996. Am J Public Health. 1998;88:1801–1806.PubMedCrossRef
68.
Zurück zum Zitat Des Jarlais DC, Marmor M, Friedmann P, et al. HIV incidence among injection drug users in New York City, 1992–1997: evidence for a declining epidemic. Am J Public Health. 2000;90:352–359.PubMedCrossRef Des Jarlais DC, Marmor M, Friedmann P, et al. HIV incidence among injection drug users in New York City, 1992–1997: evidence for a declining epidemic. Am J Public Health. 2000;90:352–359.PubMedCrossRef
69.
Zurück zum Zitat Friedman SR, Curtis R, Neaigus A, Jose B, Des Jarlais DC. Social networks, drug injectors’ lives, and HIV/AIDS. New York: Kluwer/Plenum; 1999. Friedman SR, Curtis R, Neaigus A, Jose B, Des Jarlais DC. Social networks, drug injectors’ lives, and HIV/AIDS. New York: Kluwer/Plenum; 1999.
72.
Zurück zum Zitat Tempalski B, Flom PL, Friedman SR, et al. Social and political factors predicting the presence of syringe exchange programs in 96 Metropolitan areas in the United States. Am J Public Health. 2007;97:437–447. doi:10.2105/AJPH.2005.065961.PubMedCrossRef Tempalski B, Flom PL, Friedman SR, et al. Social and political factors predicting the presence of syringe exchange programs in 96 Metropolitan areas in the United States. Am J Public Health. 2007;97:437–447. doi:10.​2105/​AJPH.​2005.​065961.PubMedCrossRef
73.
Zurück zum Zitat Tempalski B, Cooper H, Friedman SR, Des Jarlais DC, Brady J. Correlates of syringe coverage for heroin injection in 35 large metropolitan areas in the US in which heroin is the dominant injected drug. Int J Drug Policy. 2008;19S:S47–S58. doi:10.1016/j.drugpo.2007.11.011.CrossRef Tempalski B, Cooper H, Friedman SR, Des Jarlais DC, Brady J. Correlates of syringe coverage for heroin injection in 35 large metropolitan areas in the US in which heroin is the dominant injected drug. Int J Drug Policy. 2008;19S:S47–S58. doi:10.​1016/​j.​drugpo.​2007.​11.​011.CrossRef
Metadaten
Titel
HIV Prevalence Rates among Injection Drug Users in 96 Large US Metropolitan Areas, 1992–2002
verfasst von
Barbara Tempalski
Spencer Lieb
Charles M. Cleland
Hannah Cooper
Joanne E. Brady
Samuel R. Friedman
Publikationsdatum
01.01.2009
Verlag
Springer US
Erschienen in
Journal of Urban Health / Ausgabe 1/2009
Print ISSN: 1099-3460
Elektronische ISSN: 1468-2869
DOI
https://doi.org/10.1007/s11524-008-9328-1

Weitere Artikel der Ausgabe 1/2009

Journal of Urban Health 1/2009 Zur Ausgabe

Literature in Brief

Literature in Brief