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Erschienen in: Current Atherosclerosis Reports 4/2012

01.08.2012 | Cardiovascular Disease and Stroke (M Fink and J Safdieh, Section Editors)

Intracranial Hemorrhage in Patients with Cancer

verfasst von: Alan J. Velander, Lisa M. DeAngelis, Babak B. Navi

Erschienen in: Current Atherosclerosis Reports | Ausgabe 4/2012

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Abstract

Intracranial hemorrhage (ICH) is a common neurological emergency in patients with cancer, typically occurring late in the disease course, although it occasionally heralds the cancer diagnosis. ICH in these patients often occurs from unique mechanisms, especially intratumoral hemorrhage or coagulopathy, whereas hypertensive hemorrhage is rare. Lung, melanoma, breast, and glioblastoma multiforme are the most commonly associated solid tumors, partly because of their ubiquity and frequent brain involvement, whereas leukemia is the most commonly associated hematological cancer. Patients typically present with focal neurological deficits, headache, and encephalopathy, and their initial diagnostic evaluation and management should follow standard guidelines, although steroids and/or surgical resection should be strongly considered in those with intratumoral hemorrhage. Short-term outcomes are comparable to ICH in the community, whereas long-term outcomes are generally poor, corresponding to the prognosis of the underlying cancer. This review focuses on the recent advances and special considerations in cancer-related intracranial hemorrhage.
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Metadaten
Titel
Intracranial Hemorrhage in Patients with Cancer
verfasst von
Alan J. Velander
Lisa M. DeAngelis
Babak B. Navi
Publikationsdatum
01.08.2012
Verlag
Current Science Inc.
Erschienen in
Current Atherosclerosis Reports / Ausgabe 4/2012
Print ISSN: 1523-3804
Elektronische ISSN: 1534-6242
DOI
https://doi.org/10.1007/s11883-012-0250-3

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