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Current Neurology and Neuroscience Reports
Erschienen in: Current Neurology and Neuroscience Reports 2/2014

01.02.2014 | Headache (R Halker, Section Editor)

Migralepsy: A Borderland of Wavy Lines

verfasst von: Amy Z. Crepeau

Erschienen in: Current Neurology and Neuroscience Reports | Ausgabe 2/2014

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Abstract

The special relationship between migraine and epilepsy has been recognized for centuries and was formally acknowledged by Gowers in his 1906 lecture “Borderland of Epilepsy.” The term migralepsy was introduced by Lennox and Lennox in 1960, with multiple cases described in the literature since that time. In the ensuing years, the relationship between migraine and epilepsy has proven complex. The 2 conditions have been found to be comorbid with each other, suggesting a common underlying mechanism or genetic tendency. Specific diseases with both phenotypes provide further evidence of a common pathophysiology, and as the mechanism of migraine has been further elucidated, commonalities with seizure have been recognized. The terms “hemicrania epileptica” and “migraine triggered seizure” were defined by the International Headache Society, formalizing the concept that one can lead to the other. However, case reports and case series in the literature reveal that distinguishing between the 2 entities can be challenging. The concept of migralepsy is likely to evolve as greater understanding of both conditions is gained.
Literatur
1.
2.
Lennox WG. Epilepsy and related disorders. Boston: Little; 1960.
3.
Vos T, Flaxman AD, Naghavi M, et al. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380:2163–96.PubMedCrossRef
4.
Stewart WF, Lipton RB, Celentano DD, Reed ML. Prevalence of migraine headache in the United States. Relation to age, income, race, and other sociodemographic factors. JAMA. 1992;267:64–9.PubMedCrossRef
5.
Hu XH, Markson LE, Lipton RB, Stewart WF, Berger ML. Burden of migraine in the United States: disability and economic costs. Arch Intern Med. 1999;159:813–8.PubMedCrossRef
6.
England MJ, Liverman CT, Schultz AM, Strawbridge LM. Epilepsy across the spectrum: promoting health and understanding. A summary of the Institute of Medicine report. Epilepsy Behav. 2012;25:266–76.PubMedCentralPubMedCrossRef
7.
Hauser WA, Annegers JF, Kurland LT. Incidence of epilepsy and unprovoked seizures in Rochester, Minnesota: 1935-1984. Epilepsia. 1993;34:453–68.PubMedCrossRef
8.
Vivas AC, Baaj AA, Benbadis SR, Vale FL. The health care burden of patients with epilepsy in the United States: an analysis of a nationwide database over 15 years. Neurosurg Focus. 2012;32:E1.PubMedCrossRef
9.
10.
Yamane LE, Montenegro MA, Guerreiro MM. Comorbidity headache and epilepsy in childhood. Neuropediatrics. 2004;35:99–102.PubMedCrossRef
11.
Giroud M, Couillault G, Arnould S, Dauvergne M, Dumas R, Nivelon JL. Epilepsy with rolandic paroxysms and migraine, a non-fortuitous association. Results of a controlled study. Pediatrie. 1989;44:659–64.PubMed
12.
Wirrell EC, Hamiwka LD. Do children with benign rolandic epilepsy have a higher prevalence of migraine than those with other partial epilepsies or nonepilepsy controls? Epilepsia. 2006;47:1674–81.PubMedCrossRef
13.
14.
Ludvigsson P, Hesdorffer D, Olafsson E, Kjartansson O, Hauser WA. Migraine with aura is a risk factor for unprovoked seizures in children. Ann Neurol. 2006;59:210–3.PubMedCrossRef
15.
16.
Brodtkorb E, Bakken IJ, Sjaastad O. Comorbidity of migraine and epilepsy in a Norwegian community. Eur J Neurol. 2008;15:1421–3.PubMedCrossRef
17.•
Tonini MC, Giordano L, Atzeni L, et al. Primary headache and epilepsy: a multi-center cross-sectional study. Epilepsy Behav. 2012;23:342–7. Multicenter study examining the comorbidity of epilepsy and primary headache.
18.
Deprez L, Peeters K, Van Paesschen W, et al. Familial occipitotemporal lobe epilepsy and migraine with visual aura: linkage to chromosome 9q. Neurology. 2007;68:1995–2002.PubMedCrossRef
19.
Tikka-Kleemola P, Artto V, Vepsalainen S, et al. A visual migraine aura locus maps to 9q21-q22. Neurology. 2010;74:1171–7.PubMedCrossRef
20.
Klopstock T, May A, Seibel P, Papagiannuli E, Diener HC, Reichmann H. Mitochondrial DNA in migraine with aura. Neurology. 1996;46:1735–8.PubMedCrossRef
21.
Engelsen BA, Tzoulis C, Karlsen B, et al. POLG1 mutations cause a syndromic epilepsy with occipital lobe predilection. Brain. 2008;131:818–28.PubMedCrossRef
22.
Cevoli S, Pallotti F, La Morgia C, et al. High frequency of migraine-only patients negative for the 3243 A > G tRNALeu mtDNA mutation in two MELAS families. Cephalalgia. 2010;30:919–27.PubMed
23.
Crompton DE, Berkovic SF. The borderland of epilepsy: clinical and molecular features of phenomena that mimic epileptic seizures. Lancet Neurol. 2009;8:370–81.PubMedCrossRef
24.
Rajakulendran S, Kaski D, Hanna MG. Neuronal P/Q-type calcium channel dysfunction in inherited disorders of the CNS. Nat Rev Neurol. 2012;8:86–96.PubMedCrossRef
25.
Vanmolkot KR, Kors EE, Hottenga JJ, et al. Novel mutations in the Na+, K + -ATPase pump gene ATP1A2 associated with familial hemiplegic migraine and benign familial infantile convulsions. Ann Neurol. 2003;54:360–6.PubMedCrossRef
26.
Dichgans M, Freilinger T, Eckstein G, et al. Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine. Lancet. 2005;366:371–7.PubMedCrossRef
27.
Tfelt-Hansen PC. History of migraine with aura and cortical spreading depression from 1941 and onwards. Cephalalgia. 2010;30:780–92.PubMed
28.
Shatillo A, Koroleva K, Giniatullina R, et al. Cortical spreading depression induces oxidative stress in the trigeminal nociceptive system. Neuroscience. 2013;253:341–9.
29.
Herreras O, Largo C, Ibarz JM, Somjen GG, Martin del Rio R. Role of neuronal synchronizing mechanisms in the propagation of spreading depression in the in vivo hippocampus. J Neurosci. 1994;14:7087–98.PubMed
30.
Larrosa B, Pastor J, Lopez-Aguado L, Herreras O. A role for glutamate and glia in the fast network oscillations preceding spreading depression. Neuroscience. 2006;141:1057–68.PubMedCrossRef
31.
Noebels JL, Jasper HH. Jasper’s basic mechanisms of the epilepsies. 4th ed. New York: Oxford University Press; 2012.CrossRef
32.
Parisi P, Piccioli M, Villa MP, Buttinelli C, Kasteleijn-Nolst Trenite DG. Hypothesis on neurophysiopathological mechanisms linking epilepsy and headache. Med Hypotheses. 2008;70:1150–4.PubMedCrossRef
33.•
The International Classification of Headache Disorders, 3rd edition (beta version). Cephalalgia. 2013;33:629–808. This article presents the most recent International Classification of Headache Disorders.
34.
The International Classification of Headache Disorders, 2nd edition. Cephalalgia. 2004;24(Suppl 1):9–160
35.
Blume WT, Luders HO, Mizrahi E, Tassinari C, van Emde Boas W, Engel Jr J. Glossary of descriptive terminology for ictal semiology: report of the ILAE task force on classification and terminology. Epilepsia. 2001;42:1212–8.PubMedCrossRef
36.
Gastaut H. A new type of epilepsy: benign partial epilepsy of childhood with occipital spike-waves. Clin Electroencephalogr. 1982;13:13–22.PubMed
37.
Caraballo R, Koutroumanidis M, Panayiotopoulos CP, Fejerman N. Idiopathic childhood occipital epilepsy of Gastaut: a review and differentiation from migraine and other epilepsies. J Child Neurol. 2009;24:1536–42.PubMedCrossRef
38.
Parisi P, Kasteleijn-Nolst Trenite DG, Piccioli M, et al. A case with atypical childhood occipital epilepsy “Gastaut type”: an ictal migraine manifestation with a good response to intravenous diazepam. Epilepsia. 2007;48:2181–6.PubMedCrossRef
39.
Panayiotopoulos CP. Benign nocturnal childhood occipital epilepsy: a new syndrome with nocturnal seizures, tonic deviation of the eyes, and vomiting. J Child Neurol. 1989;4:43–9.PubMedCrossRef
40.
Caraballo R, Cersosimo R, Fejerman N. Panayiotopoulos syndrome: a prospective study of 192 patients. Epilepsia. 2007;48:1054–61.PubMedCrossRef
41.
Panayiotopoulos CP. Visual phenomena and headache in occipital epilepsy: a review, a systematic study and differentiation from migraine. Epileptic Disord. 1999;1:205–16.PubMed
42.
Panayiotopoulos CP. Elementary visual hallucinations, blindness, and headache in idiopathic occipital epilepsy: differentiation from migraine. J Neurol Neurosurg Psychiatry. 1999;66:536–40.PubMedCrossRef
43.
Dainese F, Mai R, Francione S, Mainardi F, Zanchin G, Paladin F. Ictal headache: headache as first ictal symptom in focal epilepsy. Epilepsy Behav. 2011;22:790–2.PubMedCrossRef
44.
Piccioli M, Parisi P, Tisei P, Villa MP, Buttinelli C, Kasteleijn-Nolst Trenite DG. Ictal headache and visual sensitivity. Cephalalgia. 2009;29:194–203.PubMedCrossRef
45.
Marks DA, Ehrenberg BL. Migraine-related seizures in adults with epilepsy, with EEG correlation. Neurology. 1993;43:2476–83.PubMedCrossRef
46.
Laplante P, Saint-Hilaire JM, Bouvier G. Headache as an epileptic manifestation. Neurology. 1983;33:1493–5.PubMedCrossRef
47.
Fusco L, Specchio N, Ciofetta G, Longo D, Trivisano M, Vigevano F. Migraine triggered by epileptic discharges in a Rasmussen’s encephalitis patient after surgery. Brain Dev. 2011;33:597–600.PubMedCrossRef
48.
Berg AT, Berkovic SF, Brodie MJ, et al. Revised terminology and concepts for organization of seizures and epilepsies: report of the ILAE Commission on Classification and Terminology, 2005–2009. Epilepsia. 2010;51:676–85.PubMedCrossRef
49.
Donnet A, Bartolomei F. Migraine with visual aura and photosensitive epileptic seizures. Epilepsia. 1997;38:1032–4.PubMedCrossRef
50.
Niedermeyer E. Migraine-triggered epilepsy. Clin Electroencephalogr. 1993;24:37–43.PubMed
51.
Colombo B, Dalla Libera D, Volonte MA, et al. Migralepsy: a new case confirming the existence of this migraine complication and proposing therapy. Neurol Sci. 2013;34:1465–6.PubMedCrossRef
52.
Friedenberg S, Dodick DW. Migraine-associated seizure: a case of reversible MRI abnormalities and persistent nondominant hemisphere syndrome. Headache. 2000;40:487–90.PubMedCrossRef
53.•
Verrotti A, Coppola G, Di Fonzo A, et al. Should “migralepsy” be considered an obsolete concept? A multi-center retrospective clinical/EEG study and review of the literature. Epilepsy Behav. 2011;21:52–9. Recent review of the evidence behind the concept of migralepsy.
Metadaten
Titel
Migralepsy: A Borderland of Wavy Lines
verfasst von
Amy Z. Crepeau
Publikationsdatum
01.02.2014
Verlag
Springer US
Erschienen in
Current Neurology and Neuroscience Reports / Ausgabe 2/2014
Print ISSN: 1528-4042
Elektronische ISSN: 1534-6293
DOI
https://doi.org/10.1007/s11910-013-0427-3

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