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Knee Surgery, Sports Traumatology, Arthroscopy

Erschienen in:

01.01.2014 | Knee

Is there a role for adult non-cultivated bone marrow stem cells in ACL reconstruction?

verfasst von: Alcindo Silva, Ricardo Sampaio, Rui Fernandes, Elisabete Pinto

Erschienen in: Knee Surgery, Sports Traumatology, Arthroscopy | Ausgabe 1/2014

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Abstract

Purpose

To assess by magnetic resonance imaging (MRI) if adult non-cultivated bone marrow stem cells accelerate tendon-to-bone healing in the femoral tunnel, after hamstring anterior cruciate ligament (ACL) reconstruction.

Methods

Forty-three patients underwent ACL reconstruction and were prospectively randomized into two groups: 20 patients in the experimental group (group A) with adult non-cultivated bone marrow stem cells and 23 patients in the control group (group B) without adult non-cultivated bone marrow stem cells. All patients underwent MRI of the knee at three months after surgery to evaluate the signal-to-noise ratio of the interzone.

Results

There was no difference in the signal-to-noise ratio of the interzone on MRI between the experimental and the control group.

Conclusions

Adult non-cultivated bone marrow stem cells do not seem to accelerate graft-to-bone healing in ACL reconstruction. The clinical relevance of this finding is that adult non-cultivated bone marrow stem cells apparently have a limited role in ACL reconstruction.

Level of evidence

II.

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Titel: Is there a role for adult non-cultivated bone marrow stem cells in ACL reconstruction?
verfasst von: Alcindo Silva
Ricardo Sampaio
Rui Fernandes
Elisabete Pinto
Publikationsdatum: 01.01.2014
Verlag: Springer Berlin Heidelberg
Erschienen in: Knee Surgery, Sports Traumatology, Arthroscopy / Ausgabe 1/2014
Print ISSN: 0942-2056
Elektronische ISSN: 1433-7347
DOI: https://doi.org/10.1007/s00167-012-2279-9

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Abstract

Purpose

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Level of evidence

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