Skip to main content
Erschienen in: Knee Surgery, Sports Traumatology, Arthroscopy 6/2016

16.04.2016 | Knee

The role of meniscal tissue in joint protection in early osteoarthritis

verfasst von: Rene Verdonk, Henning Madry, Nogah Shabshin, Florian Dirisamer, Giuseppe M. Peretti, Nicolas Pujol, Tim Spalding, Peter Verdonk, Romain Seil, Vincenzo Condello, Berardo Di Matteo, Johannes Zellner, Peter Angele

Erschienen in: Knee Surgery, Sports Traumatology, Arthroscopy | Ausgabe 6/2016

Einloggen, um Zugang zu erhalten

Abstract

It is widely accepted that partial meniscectomy leads to early onset of osteoarthritis (OA). A strong correlation exists between the amount and location of the resected meniscus and the development of degenerative changes in the knee. On the other hand, osteoarthritic changes of the joint alter the structural and functional integrity of meniscal tissue. These alterations might additionally compromise the limited healing capacity of the meniscus. In young, active patients without cartilage damage, meniscus therapy including partial meniscectomy, meniscus suture, and meniscus replacement has proven beneficial effects in long-term studies. Even in an early osteoarthritic milieu, there is a relevant regenerative potential of the meniscus and the surrounding cartilage. This potential should be taken into account, and meniscal surgery can be performed with the correct timing and the proper indication even in the presence of early OA.
Level of evidence IV.
Literatur
1.
Zurück zum Zitat Abdon P, Turner MS, Pettersson H, Lindstrand A, Stenstrom A, Swanson AJ (1990) A long-term follow-up study of total meniscectomy in children. Clin Orthop Relat Res 257:166–170PubMed Abdon P, Turner MS, Pettersson H, Lindstrand A, Stenstrom A, Swanson AJ (1990) A long-term follow-up study of total meniscectomy in children. Clin Orthop Relat Res 257:166–170PubMed
2.
Zurück zum Zitat Abraham AC, Pauly HM, Donahue TL (2014) Deleterious effects of osteoarthritis on the structure and function of the meniscal enthesis. Osteoarthr Cartil 22(2):275–283CrossRefPubMedPubMedCentral Abraham AC, Pauly HM, Donahue TL (2014) Deleterious effects of osteoarthritis on the structure and function of the meniscal enthesis. Osteoarthr Cartil 22(2):275–283CrossRefPubMedPubMedCentral
3.
Zurück zum Zitat Abrams GD, Frank RM, Gupta AK, Harris JD, McCormick FM, Cole BJ (2013) Trends in meniscus repair and meniscectomy in the United States, 2005-2011. Am J Sports Med 41(10):2333–2339CrossRefPubMed Abrams GD, Frank RM, Gupta AK, Harris JD, McCormick FM, Cole BJ (2013) Trends in meniscus repair and meniscectomy in the United States, 2005-2011. Am J Sports Med 41(10):2333–2339CrossRefPubMed
4.
Zurück zum Zitat Accadbled F, Cassard X, Sales de Gauzy J, Cahuzac JP (2007) Meniscal tears in children and adolescents: results of operative treatment. J Pediatr Orthop B 16(1):56–60CrossRefPubMed Accadbled F, Cassard X, Sales de Gauzy J, Cahuzac JP (2007) Meniscal tears in children and adolescents: results of operative treatment. J Pediatr Orthop B 16(1):56–60CrossRefPubMed
5.
Zurück zum Zitat Ahn JH, Kwon OJ, Nam TS (2015) Arthroscopic repair of horizontal meniscal cleavage tears with marrow-stimulating technique. Arthroscopy 31(1):92–98CrossRefPubMed Ahn JH, Kwon OJ, Nam TS (2015) Arthroscopic repair of horizontal meniscal cleavage tears with marrow-stimulating technique. Arthroscopy 31(1):92–98CrossRefPubMed
6.
Zurück zum Zitat Allen CR, Wong EK, Livesay GA, Sakane M, Fu FH, Woo SL (2000) Importance of the medial meniscus in the anterior cruciate ligament-deficient knee. J Orthop Res 18(1):109–115CrossRefPubMed Allen CR, Wong EK, Livesay GA, Sakane M, Fu FH, Woo SL (2000) Importance of the medial meniscus in the anterior cruciate ligament-deficient knee. J Orthop Res 18(1):109–115CrossRefPubMed
7.
Zurück zum Zitat Andrish JT (1996) Meniscal injuries in children and adolescents: diagnosis and management. J Am Acad Orthop Surg 4(5):231–237CrossRefPubMed Andrish JT (1996) Meniscal injuries in children and adolescents: diagnosis and management. J Am Acad Orthop Surg 4(5):231–237CrossRefPubMed
9.
Zurück zum Zitat Angele P, Muller R, Schumann D, Englert C, Zellner J, Johnstone B, Yoo J, Hammer J, Fierlbeck J, Angele MK, Nerlich M, Kujat R (2009) Characterization of esterified hyaluronan-gelatin polymer composites suitable for chondrogenic differentiation of mesenchymal stem cells. J Biomed Mater Res A 91(2):416–427CrossRefPubMedPubMedCentral Angele P, Muller R, Schumann D, Englert C, Zellner J, Johnstone B, Yoo J, Hammer J, Fierlbeck J, Angele MK, Nerlich M, Kujat R (2009) Characterization of esterified hyaluronan-gelatin polymer composites suitable for chondrogenic differentiation of mesenchymal stem cells. J Biomed Mater Res A 91(2):416–427CrossRefPubMedPubMedCentral
10.
Zurück zum Zitat Beaufils P, Hulet C, Dhenain M, Nizard R, Nourissat G, Pujol N (2009) Clinical practice guidelines for the management of meniscal lesions and isolated lesions of the anterior cruciate ligament of the knee in adults. Orthop Traumatol Surg Res 95(6):437–442CrossRefPubMed Beaufils P, Hulet C, Dhenain M, Nizard R, Nourissat G, Pujol N (2009) Clinical practice guidelines for the management of meniscal lesions and isolated lesions of the anterior cruciate ligament of the knee in adults. Orthop Traumatol Surg Res 95(6):437–442CrossRefPubMed
11.
Zurück zum Zitat Bhattacharyya T, Gale D, Dewire P, Totterman S, Gale ME, McLaughlin S, Einhorn TA, Felson DT (2003) The clinical importance of meniscal tears demonstrated by magnetic resonance imaging in osteoarthritis of the knee. J Bone Joint Surg Am 85(1):4–9PubMed Bhattacharyya T, Gale D, Dewire P, Totterman S, Gale ME, McLaughlin S, Einhorn TA, Felson DT (2003) The clinical importance of meniscal tears demonstrated by magnetic resonance imaging in osteoarthritis of the knee. J Bone Joint Surg Am 85(1):4–9PubMed
12.
Zurück zum Zitat Biedert RM (1993) Intrasubstance meniscal tears. Clinical aspects and the role of MRI. Arch Orthop Trauma Surg 112(3):142–147CrossRefPubMed Biedert RM (1993) Intrasubstance meniscal tears. Clinical aspects and the role of MRI. Arch Orthop Trauma Surg 112(3):142–147CrossRefPubMed
13.
Zurück zum Zitat Bloecker K, Guermazi A, Wirth W, Benichou O, Kwoh CK, Hunter DJ, Englund M, Resch H, Eckstein F, Investigators OAI (2013) Tibial coverage, meniscus position, size and damage in knees discordant for joint space narrowing—data from the Osteoarthritis Initiative. Osteoarthr Cartil 21(3):419–427CrossRefPubMedPubMedCentral Bloecker K, Guermazi A, Wirth W, Benichou O, Kwoh CK, Hunter DJ, Englund M, Resch H, Eckstein F, Investigators OAI (2013) Tibial coverage, meniscus position, size and damage in knees discordant for joint space narrowing—data from the Osteoarthritis Initiative. Osteoarthr Cartil 21(3):419–427CrossRefPubMedPubMedCentral
14.
Zurück zum Zitat Bloecker K, Wirth W, Guermazi A, Hunter DJ, Resch H, Hochreiter J, Eckstein F (2015) Medial meniscal extrusion relates to cartilage loss in specific femorotibial subregions-data from the osteoarthritis initiative. Arthritis Care Res (Hoboken) 67(11):1545–1552CrossRef Bloecker K, Wirth W, Guermazi A, Hunter DJ, Resch H, Hochreiter J, Eckstein F (2015) Medial meniscal extrusion relates to cartilage loss in specific femorotibial subregions-data from the osteoarthritis initiative. Arthritis Care Res (Hoboken) 67(11):1545–1552CrossRef
15.
Zurück zum Zitat Bouyarmane H, Beaufils P, Pujol N, Bellemans J, Roberts S, Spalding T, Zaffagnini S, Marcacci M, Verdonk P, Womack M, Verdonk R (2014) Polyurethane scaffold in lateral meniscus segmental defects: clinical outcomes at 24 months follow-up. Orthop Traumatol Surg Res 100(1):153–157CrossRefPubMed Bouyarmane H, Beaufils P, Pujol N, Bellemans J, Roberts S, Spalding T, Zaffagnini S, Marcacci M, Verdonk P, Womack M, Verdonk R (2014) Polyurethane scaffold in lateral meniscus segmental defects: clinical outcomes at 24 months follow-up. Orthop Traumatol Surg Res 100(1):153–157CrossRefPubMed
16.
Zurück zum Zitat Bulgheroni P, Murena L, Ratti C, Bulgheroni E, Ronga M, Cherubino P (2010) Follow-up of collagen meniscus implant patients: clinical, radiological, and magnetic resonance imaging results at 5 years. Knee 17(3):224–229CrossRefPubMed Bulgheroni P, Murena L, Ratti C, Bulgheroni E, Ronga M, Cherubino P (2010) Follow-up of collagen meniscus implant patients: clinical, radiological, and magnetic resonance imaging results at 5 years. Knee 17(3):224–229CrossRefPubMed
17.
Zurück zum Zitat Busch MT (1990) Meniscal injuries in children and adolescents. Clin Sports Med 9(3):661–680PubMed Busch MT (1990) Meniscal injuries in children and adolescents. Clin Sports Med 9(3):661–680PubMed
18.
Zurück zum Zitat Caplan AI, Dennis JE (2006) Mesenchymal stem cells as trophic mediators. J Cell Biochem 98(5):1076–1084CrossRefPubMed Caplan AI, Dennis JE (2006) Mesenchymal stem cells as trophic mediators. J Cell Biochem 98(5):1076–1084CrossRefPubMed
19.
Zurück zum Zitat Cicuttini FM, Forbes A, Yuanyuan W, Rush G, Stuckey SL (2002) Rate of knee cartilage loss after partial meniscectomy. J Rheumatol 29(9):1954–1956PubMed Cicuttini FM, Forbes A, Yuanyuan W, Rush G, Stuckey SL (2002) Rate of knee cartilage loss after partial meniscectomy. J Rheumatol 29(9):1954–1956PubMed
20.
Zurück zum Zitat Crues JV 3rd, Mink J, Levy TL, Lotysch M, Stoller DW (1987) Meniscal tears of the knee: accuracy of MR imaging. Radiology 164(2):445–448CrossRefPubMed Crues JV 3rd, Mink J, Levy TL, Lotysch M, Stoller DW (1987) Meniscal tears of the knee: accuracy of MR imaging. Radiology 164(2):445–448CrossRefPubMed
21.
Zurück zum Zitat de Girolamo L, Galliera E, Volpi P, Denti M, Dogliotti G, Quaglia A, Cabitza P, Corsi Romanelli MM, Randelli P (2015) Why menisci show higher healing rate when repaired during ACL reconstruction? Growth factors release can be the explanation. Knee Surg Sports Traumatol Arthrosc 23(1):90–96CrossRefPubMed de Girolamo L, Galliera E, Volpi P, Denti M, Dogliotti G, Quaglia A, Cabitza P, Corsi Romanelli MM, Randelli P (2015) Why menisci show higher healing rate when repaired during ACL reconstruction? Growth factors release can be the explanation. Knee Surg Sports Traumatol Arthrosc 23(1):90–96CrossRefPubMed
22.
Zurück zum Zitat De Smet AA, Norris MA, Yandow DR, Quintana FA, Graf BK, Keene JS (1993) MR diagnosis of meniscal tears of the knee: importance of high signal in the meniscus that extends to the surface. Am J Roentgenol 161(1):101–107CrossRef De Smet AA, Norris MA, Yandow DR, Quintana FA, Graf BK, Keene JS (1993) MR diagnosis of meniscal tears of the knee: importance of high signal in the meniscus that extends to the surface. Am J Roentgenol 161(1):101–107CrossRef
23.
Zurück zum Zitat De Smet AA, Tuite MJ (2006) Use of the “two-slice-touch” rule for the MRI diagnosis of meniscal tears. Am J Roentgenol 187(4):911–914CrossRef De Smet AA, Tuite MJ (2006) Use of the “two-slice-touch” rule for the MRI diagnosis of meniscal tears. Am J Roentgenol 187(4):911–914CrossRef
24.
Zurück zum Zitat Di Matteo B, Perdisa F, Gostynska N, Kon E, Filardo G, Marcacci M (2015) Meniscal scaffolds—preclinical evidence to support their use: a systematic review. Open Orthop J 15(9):143–156CrossRef Di Matteo B, Perdisa F, Gostynska N, Kon E, Filardo G, Marcacci M (2015) Meniscal scaffolds—preclinical evidence to support their use: a systematic review. Open Orthop J 15(9):143–156CrossRef
25.
Zurück zum Zitat Elsner JJ, Portnoy S, Guilak F, Shterling A, Linder-Ganz E (2010) MRI-based characterization of bone anatomy in the human knee for size matching of a medial meniscal implant. J Biomech Eng 132(10):101008CrossRefPubMed Elsner JJ, Portnoy S, Guilak F, Shterling A, Linder-Ganz E (2010) MRI-based characterization of bone anatomy in the human knee for size matching of a medial meniscal implant. J Biomech Eng 132(10):101008CrossRefPubMed
26.
Zurück zum Zitat Elsner JJ, Portnoy S, Zur G, Guilak F, Shterling A, Linder-Ganz E (2010) Design of a free-floating polycarbonate-urethane meniscal implant using finite element modeling and experimental validation. J Biomech Eng 132(9):095001CrossRefPubMed Elsner JJ, Portnoy S, Zur G, Guilak F, Shterling A, Linder-Ganz E (2010) Design of a free-floating polycarbonate-urethane meniscal implant using finite element modeling and experimental validation. J Biomech Eng 132(9):095001CrossRefPubMed
27.
Zurück zum Zitat Englund M, Lohmander LS (2004) Risk factors for symptomatic knee osteoarthritis fifteen to twenty-two years after meniscectomy. Arthritis Rheum 50(9):2811–2819CrossRefPubMed Englund M, Lohmander LS (2004) Risk factors for symptomatic knee osteoarthritis fifteen to twenty-two years after meniscectomy. Arthritis Rheum 50(9):2811–2819CrossRefPubMed
28.
Zurück zum Zitat Englund M, Roos EM, Roos HP, Lohmander LS (2001) Patient-relevant outcomes fourteen years after meniscectomy: influence of type of meniscal tear and size of resection. Rheumatology (Oxford) 40(6):631–639CrossRef Englund M, Roos EM, Roos HP, Lohmander LS (2001) Patient-relevant outcomes fourteen years after meniscectomy: influence of type of meniscal tear and size of resection. Rheumatology (Oxford) 40(6):631–639CrossRef
29.
Zurück zum Zitat Fairbank TJ (1948) Knee joint changes after meniscectomy. J Bone Joint Surg Br 30B(4):664–670PubMed Fairbank TJ (1948) Knee joint changes after meniscectomy. J Bone Joint Surg Br 30B(4):664–670PubMed
30.
Zurück zum Zitat Filardo G, Andriolo L, Kon E, de Caro F, Marcacci M (2015) Meniscal scaffolds: results and indications A systematic literature review. Int Orthop 39(1):35–46CrossRefPubMed Filardo G, Andriolo L, Kon E, de Caro F, Marcacci M (2015) Meniscal scaffolds: results and indications A systematic literature review. Int Orthop 39(1):35–46CrossRefPubMed
31.
Zurück zum Zitat Filardo G, Kon E, Roffi A, Di Matteo B, Merli ML, Marcacci M (2015) Platelet-rich plasma: why intra-articular? A systematic review of preclinical studies and clinical evidence on PRP for joint degeneration. Knee Surg Sports Traumatol Arthrosc 9:2459–2474CrossRef Filardo G, Kon E, Roffi A, Di Matteo B, Merli ML, Marcacci M (2015) Platelet-rich plasma: why intra-articular? A systematic review of preclinical studies and clinical evidence on PRP for joint degeneration. Knee Surg Sports Traumatol Arthrosc 9:2459–2474CrossRef
32.
Zurück zum Zitat Grossman JW, De SmetAA, Shinki K (2009) Comparison of the accuracy rates of 3-T and 1.5-T MRI of the knee in the diagnosis of meniscal tear. Am J Roentgenol 193(2):509–514CrossRef Grossman JW, De SmetAA, Shinki K (2009) Comparison of the accuracy rates of 3-T and 1.5-T MRI of the knee in the diagnosis of meniscal tear. Am J Roentgenol 193(2):509–514CrossRef
33.
Zurück zum Zitat Herrlin SV, Wange PO, Lapidus G, Hallander M, Werner S, Weidenhielm L (2013) Is arthroscopic surgery beneficial in treating non-traumatic, degenerative medial meniscal tears? A five year follow-up. Knee Surg Sports Traumatol Arthrosc 21(2):358–364CrossRefPubMed Herrlin SV, Wange PO, Lapidus G, Hallander M, Werner S, Weidenhielm L (2013) Is arthroscopic surgery beneficial in treating non-traumatic, degenerative medial meniscal tears? A five year follow-up. Knee Surg Sports Traumatol Arthrosc 21(2):358–364CrossRefPubMed
34.
Zurück zum Zitat Hirschmann MT, Keller L, Hirschmann A, Schenk L, Berbig R, Lüthi U, Amsler F, Friederich NF, Arnold MP (2013) One-year clinical and MR imaging outcome after partial meniscal replacement in stabilized knees using a collagen meniscus implant. Knee Surg Sports Traumatol Arthrosc 21(3):740–747CrossRefPubMed Hirschmann MT, Keller L, Hirschmann A, Schenk L, Berbig R, Lüthi U, Amsler F, Friederich NF, Arnold MP (2013) One-year clinical and MR imaging outcome after partial meniscal replacement in stabilized knees using a collagen meniscus implant. Knee Surg Sports Traumatol Arthrosc 21(3):740–747CrossRefPubMed
35.
Zurück zum Zitat Horie M, Sekiya I, Muneta T, Ichinose S, Matsumoto K, Saito H, Murakami T, Kobayashi E (2009) Intra-articular Injected synovial stem cells differentiate into meniscal cells directly and promote meniscal regeneration without mobilization to distant organs in rat massive meniscal defect. Stem Cells 27(4):878–887CrossRefPubMed Horie M, Sekiya I, Muneta T, Ichinose S, Matsumoto K, Saito H, Murakami T, Kobayashi E (2009) Intra-articular Injected synovial stem cells differentiate into meniscal cells directly and promote meniscal regeneration without mobilization to distant organs in rat massive meniscal defect. Stem Cells 27(4):878–887CrossRefPubMed
36.
Zurück zum Zitat Hulet C, Schiltz D, Locker B, Beguin J, Vielpeau C (1998) Lateral meniscal cyst. Retrospective study of 105 cysts treated with arthroscopy with 5 year follow-up. Rev Chir Orthop Reparatrice Appar Mot 84(6):531–538PubMed Hulet C, Schiltz D, Locker B, Beguin J, Vielpeau C (1998) Lateral meniscal cyst. Retrospective study of 105 cysts treated with arthroscopy with 5 year follow-up. Rev Chir Orthop Reparatrice Appar Mot 84(6):531–538PubMed
37.
Zurück zum Zitat Ishimura M, Tamai S, Fujisawa Y (1991) Arthroscopic meniscal repair with fibrin glue. Arthroscopy 7(2):177–181CrossRefPubMed Ishimura M, Tamai S, Fujisawa Y (1991) Arthroscopic meniscal repair with fibrin glue. Arthroscopy 7(2):177–181CrossRefPubMed
38.
Zurück zum Zitat Jung JY, Yoon YC, Kim HR, Choe BK, Wang JH, Jung JY (2013) Knee derangements: comparison of isotropic 3D fast spin-echo, isotropic 3D balanced fast field-echo, and conventional 2D fast spin-echo MR imaging. Radiology 268(3):802–813CrossRefPubMed Jung JY, Yoon YC, Kim HR, Choe BK, Wang JH, Jung JY (2013) Knee derangements: comparison of isotropic 3D fast spin-echo, isotropic 3D balanced fast field-echo, and conventional 2D fast spin-echo MR imaging. Radiology 268(3):802–813CrossRefPubMed
39.
Zurück zum Zitat Jung JY, Yoon YC, Kwon JW, Ahn JH, Choe BK (2009) Diagnosis of internal derangement of the knee at 3.0-T MR imaging: 3D isotropic intermediate-weighted versus 2D sequences. Radiology 253(3):780–787CrossRefPubMed Jung JY, Yoon YC, Kwon JW, Ahn JH, Choe BK (2009) Diagnosis of internal derangement of the knee at 3.0-T MR imaging: 3D isotropic intermediate-weighted versus 2D sequences. Radiology 253(3):780–787CrossRefPubMed
40.
Zurück zum Zitat Katz JN, Brophy RH, Chaisson CE, de Chaves L, Cole BJ, Dahm DL, Donnell-Fink LA, Guermazi A, Haas AK, Jones MH, Levy BA, Mandl LA, Martin SD, Marx RG, Miniaci A, Matava MJ, Palmisano J, Reinke EK, Richardson BE, Rome BN, Safran-Norton CE, Skoniecki DJ, Solomon DH, Smith MV, Spindler KP, Stuart MJ, Wright J, Wright RW, Losina E (2013) Surgery versus physical therapy for a meniscal tear and osteoarthritis. N Engl J Med 368(18):1675–1684CrossRefPubMedPubMedCentral Katz JN, Brophy RH, Chaisson CE, de Chaves L, Cole BJ, Dahm DL, Donnell-Fink LA, Guermazi A, Haas AK, Jones MH, Levy BA, Mandl LA, Martin SD, Marx RG, Miniaci A, Matava MJ, Palmisano J, Reinke EK, Richardson BE, Rome BN, Safran-Norton CE, Skoniecki DJ, Solomon DH, Smith MV, Spindler KP, Stuart MJ, Wright J, Wright RW, Losina E (2013) Surgery versus physical therapy for a meniscal tear and osteoarthritis. N Engl J Med 368(18):1675–1684CrossRefPubMedPubMedCentral
41.
Zurück zum Zitat Khan M, Evaniew N, Bedi A, Ayeni OR, Bhandari M (2014) Arthroscopic surgery for degenerative tears of the meniscus: a systematic review and meta-analysis. CMAJ 186(14):1057–1064CrossRefPubMedPubMedCentral Khan M, Evaniew N, Bedi A, Ayeni OR, Bhandari M (2014) Arthroscopic surgery for degenerative tears of the meniscus: a systematic review and meta-analysis. CMAJ 186(14):1057–1064CrossRefPubMedPubMedCentral
42.
Zurück zum Zitat Kraus T, Heidari N, Svehlik M, Schneider F, Sperl M, Linhart W (2012) Outcome of repaired unstable meniscal tears in children and adolescents. Acta Orthop 83(3):261–266CrossRefPubMedPubMedCentral Kraus T, Heidari N, Svehlik M, Schneider F, Sperl M, Linhart W (2012) Outcome of repaired unstable meniscal tears in children and adolescents. Acta Orthop 83(3):261–266CrossRefPubMedPubMedCentral
43.
Zurück zum Zitat Kurzweil PR, Lynch NM, Coleman S, Kearney B (2014) Repair of horizontal meniscus tears: a systematic review. Arthroscopy 30(11):1513–1519CrossRefPubMed Kurzweil PR, Lynch NM, Coleman S, Kearney B (2014) Repair of horizontal meniscus tears: a systematic review. Arthroscopy 30(11):1513–1519CrossRefPubMed
44.
Zurück zum Zitat Lee SY, Jee WH, Kim JM (2008) Radial tear of the medial meniscal root: reliability and accuracy of MRI for diagnosis. Am J Roentgenol 191(1):81–85CrossRef Lee SY, Jee WH, Kim JM (2008) Radial tear of the medial meniscal root: reliability and accuracy of MRI for diagnosis. Am J Roentgenol 191(1):81–85CrossRef
45.
Zurück zum Zitat Linder-Ganz E, Elsner JJ, Danino A, Guilak F, Shterling A (2010) A novel quantitative approach for evaluating contact mechanics of meniscal replacements. J Biomech Eng 132(2):024501CrossRefPubMed Linder-Ganz E, Elsner JJ, Danino A, Guilak F, Shterling A (2010) A novel quantitative approach for evaluating contact mechanics of meniscal replacements. J Biomech Eng 132(2):024501CrossRefPubMed
46.
Zurück zum Zitat Madry H, Luyten FP, Facchini A (2012) Biological aspects of early osteoarthritis. Knee Surg Sports Traumatol Arthrosc 20(3):407–422CrossRefPubMed Madry H, Luyten FP, Facchini A (2012) Biological aspects of early osteoarthritis. Knee Surg Sports Traumatol Arthrosc 20(3):407–422CrossRefPubMed
47.
Zurück zum Zitat Madry H, Ziegler R, Orth P, Goebel L, Ong MF, Kohn D, Cucchiarini M, Pape D (2013) Effect of open wedge high tibial osteotomy on the lateral compartment in sheep. Part I: analysis of the lateral meniscus. Knee Surg Sports Traumatol Arthrosc 21(1):39–48CrossRefPubMed Madry H, Ziegler R, Orth P, Goebel L, Ong MF, Kohn D, Cucchiarini M, Pape D (2013) Effect of open wedge high tibial osteotomy on the lateral compartment in sheep. Part I: analysis of the lateral meniscus. Knee Surg Sports Traumatol Arthrosc 21(1):39–48CrossRefPubMed
48.
Zurück zum Zitat Manzione M, Pizzutillo PD, Peoples AB, Schweizer PA (1983) Meniscectomy in children: a long-term follow-up study. Am J Sports Med 11(3):111–115CrossRefPubMed Manzione M, Pizzutillo PD, Peoples AB, Schweizer PA (1983) Meniscectomy in children: a long-term follow-up study. Am J Sports Med 11(3):111–115CrossRefPubMed
49.
Zurück zum Zitat Matsukura Y, Muneta T, Tsuji K, Koga H, Sekiya I (2014) Mesenchymal stem cells in synovial fluid increase after meniscus injury. Clin Orthop Relat Res 472(5):1357–1364CrossRefPubMedPubMedCentral Matsukura Y, Muneta T, Tsuji K, Koga H, Sekiya I (2014) Mesenchymal stem cells in synovial fluid increase after meniscus injury. Clin Orthop Relat Res 472(5):1357–1364CrossRefPubMedPubMedCentral
50.
Zurück zum Zitat McNicholas MJ, Rowley DI, McGurty D, Adalberth T, Abdon P, Lindstrand A, Lohmander LS (2000) Total meniscectomy in adolescence. A thirty-year follow-up. J Bone Joint Surg Br 82(2):217–221CrossRefPubMed McNicholas MJ, Rowley DI, McGurty D, Adalberth T, Abdon P, Lindstrand A, Lohmander LS (2000) Total meniscectomy in adolescence. A thirty-year follow-up. J Bone Joint Surg Br 82(2):217–221CrossRefPubMed
51.
Zurück zum Zitat Mintzer CM, Richmond JC, Taylor J (1998) Meniscal repair in the young athlete. Am J Sports Med 26(5):630–633PubMed Mintzer CM, Richmond JC, Taylor J (1998) Meniscal repair in the young athlete. Am J Sports Med 26(5):630–633PubMed
52.
Zurück zum Zitat Mitchell J, Graham W, Best TM, Collins C, Currie DW, Comstock RD, Flanigan DC (2015) Epidemiology of meniscal injuries in US high school athletes between 2007 and 2013. Knee Surg Sports Traumatol Arthrosc. doi:10.1007/s00167-015-3814-2 PubMed Mitchell J, Graham W, Best TM, Collins C, Currie DW, Comstock RD, Flanigan DC (2015) Epidemiology of meniscal injuries in US high school athletes between 2007 and 2013. Knee Surg Sports Traumatol Arthrosc. doi:10.​1007/​s00167-015-3814-2 PubMed
53.
Zurück zum Zitat Monllau JC, Gelber PE, Abat F, Pelfort X, Abad R, Hinarejos P, Tey M (2011) Outcome after partial medial meniscus substitution with the collagen meniscal implant at a minimum of 10 years’ follow-up. Arthroscopy 27(7):933–943CrossRefPubMed Monllau JC, Gelber PE, Abat F, Pelfort X, Abad R, Hinarejos P, Tey M (2011) Outcome after partial medial meniscus substitution with the collagen meniscal implant at a minimum of 10 years’ follow-up. Arthroscopy 27(7):933–943CrossRefPubMed
54.
Zurück zum Zitat Moran CJ, Withers DP, Kurzweil PR, Verdonk PC (2015) Clinical application of scaffolds for partial meniscus replacement. Sports Med Arthrosc Rev 23(3):156–161CrossRef Moran CJ, Withers DP, Kurzweil PR, Verdonk PC (2015) Clinical application of scaffolds for partial meniscus replacement. Sports Med Arthrosc Rev 23(3):156–161CrossRef
55.
Zurück zum Zitat Moseley JB, O’Malley K, Petersen NJ, Menke TJ, Brody BA, Kuykendall DH, Hollingsworth JC, Ashton CM, Wray NP (2002) A controlled trial of arthroscopic surgery for osteoarthritis of the knee. N Engl J Med 347(2):81–88CrossRefPubMed Moseley JB, O’Malley K, Petersen NJ, Menke TJ, Brody BA, Kuykendall DH, Hollingsworth JC, Ashton CM, Wray NP (2002) A controlled trial of arthroscopic surgery for osteoarthritis of the knee. N Engl J Med 347(2):81–88CrossRefPubMed
56.
Zurück zum Zitat Noyes FR, Barber-Westin SD (2012) Treatment of meniscus tears during anterior ligament reconstruction. Arthroscopy 28(1):123–130CrossRefPubMed Noyes FR, Barber-Westin SD (2012) Treatment of meniscus tears during anterior ligament reconstruction. Arthroscopy 28(1):123–130CrossRefPubMed
57.
Zurück zum Zitat Okazaki K, Miura H, Matsuda S, Hashizume M, Iwamoto Y (2006) Arthroscopic resection of the discoid lateral meniscus: long-term follow-up for 16 years. Arthroscopy 22(9):967–971CrossRefPubMed Okazaki K, Miura H, Matsuda S, Hashizume M, Iwamoto Y (2006) Arthroscopic resection of the discoid lateral meniscus: long-term follow-up for 16 years. Arthroscopy 22(9):967–971CrossRefPubMed
58.
Zurück zum Zitat Papageorgiou CD, Gil JE, Kanamori A, Fenwick JA, Woo SL, Fu FH (2001) The biomechanical interdependence between the anterior cruciate ligament replacement graft and the medial meniscus. Am J Sports Med 29(2):226–231PubMed Papageorgiou CD, Gil JE, Kanamori A, Fenwick JA, Woo SL, Fu FH (2001) The biomechanical interdependence between the anterior cruciate ligament replacement graft and the medial meniscus. Am J Sports Med 29(2):226–231PubMed
59.
Zurück zum Zitat Paxton ES, Stock MV, Brophy RH (2011) Meniscal repair versus partial meniscectomy: a systematic review comparing reoperation rates and clinical outcomes. Arthroscopy 27(9):1275–1288CrossRefPubMed Paxton ES, Stock MV, Brophy RH (2011) Meniscal repair versus partial meniscectomy: a systematic review comparing reoperation rates and clinical outcomes. Arthroscopy 27(9):1275–1288CrossRefPubMed
60.
Zurück zum Zitat Peretti GM, Gill TJ, Xu JW, Randolph MA, Morse KR, Zaleske DJ (2004) Cell-based therapy for meniscal repair: a large animal study. Am J Sports Med 32(1):146–158CrossRefPubMed Peretti GM, Gill TJ, Xu JW, Randolph MA, Morse KR, Zaleske DJ (2004) Cell-based therapy for meniscal repair: a large animal study. Am J Sports Med 32(1):146–158CrossRefPubMed
61.
Zurück zum Zitat Pernin J, Verdonk P, Di SelmiTA, Massin P, Neyret P (2010) Long-term follow-up of 24.5 years after intra-articular anterior cruciate ligament reconstruction with lateral extra-articular augmentation. Am J Sports Med 38(6):1094–1102CrossRefPubMed Pernin J, Verdonk P, Di SelmiTA, Massin P, Neyret P (2010) Long-term follow-up of 24.5 years after intra-articular anterior cruciate ligament reconstruction with lateral extra-articular augmentation. Am J Sports Med 38(6):1094–1102CrossRefPubMed
62.
Zurück zum Zitat Petty CA, Lubowitz JH (2011) Does arthroscopic partial meniscectomy result in knee osteoarthritis? A systematic review with a minimum of 8 years’ follow-up. Arthroscopy 27(3):419–424CrossRefPubMed Petty CA, Lubowitz JH (2011) Does arthroscopic partial meniscectomy result in knee osteoarthritis? A systematic review with a minimum of 8 years’ follow-up. Arthroscopy 27(3):419–424CrossRefPubMed
63.
Zurück zum Zitat Raber DA, Friederich NF, Hefti F (1998) Discoid lateral meniscus in children. Long-term follow-up after total meniscectomy. J Bone Joint Surg Am 80(11):1579–1586PubMed Raber DA, Friederich NF, Hefti F (1998) Discoid lateral meniscus in children. Long-term follow-up after total meniscectomy. J Bone Joint Surg Am 80(11):1579–1586PubMed
64.
Zurück zum Zitat Rodkey WG, DeHaven KE, Montgomery WH 3rd, Baker CL Jr, Beck CL Jr, Hormel SE, Steadman JR, Cole BJ, Briggs KK (2008) Comparison of the collagen meniscus implant with partial meniscectomy. A prospective randomized trial. J Bone Joint Surg Am 90(7):1413–1426CrossRefPubMed Rodkey WG, DeHaven KE, Montgomery WH 3rd, Baker CL Jr, Beck CL Jr, Hormel SE, Steadman JR, Cole BJ, Briggs KK (2008) Comparison of the collagen meniscus implant with partial meniscectomy. A prospective randomized trial. J Bone Joint Surg Am 90(7):1413–1426CrossRefPubMed
65.
Zurück zum Zitat Roos EM, Ostenberg A, Roos H, Ekdahl C, Lohmander LS (2001) Long-term outcome of meniscectomy: symptoms, function, and performance tests in patients with or without radiographic osteoarthritis compared to matched controls. Osteoarthr Cartil 9(4):316–324CrossRefPubMed Roos EM, Ostenberg A, Roos H, Ekdahl C, Lohmander LS (2001) Long-term outcome of meniscectomy: symptoms, function, and performance tests in patients with or without radiographic osteoarthritis compared to matched controls. Osteoarthr Cartil 9(4):316–324CrossRefPubMed
66.
Zurück zum Zitat Roos H, Lauren M, Adalberth T, Roos EM, Jonsson K, Lohmander LS (1998) Knee osteoarthritis after meniscectomy: prevalence of radiographic changes after twenty-one years, compared with matched controls. Arthritis Rheum 41(4):687–693CrossRefPubMed Roos H, Lauren M, Adalberth T, Roos EM, Jonsson K, Lohmander LS (1998) Knee osteoarthritis after meniscectomy: prevalence of radiographic changes after twenty-one years, compared with matched controls. Arthritis Rheum 41(4):687–693CrossRefPubMed
67.
Zurück zum Zitat Ryu RK, Dunbar VW, Morse GG (2002) Meniscal allograft replacement: a 1-year to 6-year experience. Arthroscopy 18(9):989–994CrossRefPubMed Ryu RK, Dunbar VW, Morse GG (2002) Meniscal allograft replacement: a 1-year to 6-year experience. Arthroscopy 18(9):989–994CrossRefPubMed
68.
Zurück zum Zitat Sakaguchi Y, Sekiya I, Yagishita K, Muneta T (2005) Comparison of human stem cells derived from various mesenchymal tissues: superiority of synovium as a cell source. Arthritis Rheum 52(8):2521–2529CrossRefPubMed Sakaguchi Y, Sekiya I, Yagishita K, Muneta T (2005) Comparison of human stem cells derived from various mesenchymal tissues: superiority of synovium as a cell source. Arthritis Rheum 52(8):2521–2529CrossRefPubMed
69.
Zurück zum Zitat Samitier G, Alentorn-Geli E, Taylor DC, Rill B, Lock T, Moutzouros V, Kolowich P (2015) Meniscal allograft transplantation. Part 2: systematic review of transplant timing, outcomes, return to competition, associated procedures, and prevention of osteoarthritis. Knee Surg Sports Traumatol Arthrosc 23(1):323–333CrossRefPubMed Samitier G, Alentorn-Geli E, Taylor DC, Rill B, Lock T, Moutzouros V, Kolowich P (2015) Meniscal allograft transplantation. Part 2: systematic review of transplant timing, outcomes, return to competition, associated procedures, and prevention of osteoarthritis. Knee Surg Sports Traumatol Arthrosc 23(1):323–333CrossRefPubMed
71.
Zurück zum Zitat Scotti C, Hirschmann MT, Antinolfi P, Martin I, Peretti GM (2013) Meniscus repair and regeneration: review on current methods and research potential. Eur Cell Mater 26:150–170PubMed Scotti C, Hirschmann MT, Antinolfi P, Martin I, Peretti GM (2013) Meniscus repair and regeneration: review on current methods and research potential. Eur Cell Mater 26:150–170PubMed
72.
Zurück zum Zitat Sihvonen R, Paavola M, Malmivaara A, Itala A, Joukainen A, Nurmi H, Kalske J, Jarvinen TL, Finnish Degenerative Meniscal Lesion Study G (2013) Arthroscopic partial meniscectomy versus sham surgery for a degenerative meniscal tear. New Engl J Med 369(26):2515–2524CrossRefPubMed Sihvonen R, Paavola M, Malmivaara A, Itala A, Joukainen A, Nurmi H, Kalske J, Jarvinen TL, Finnish Degenerative Meniscal Lesion Study G (2013) Arthroscopic partial meniscectomy versus sham surgery for a degenerative meniscal tear. New Engl J Med 369(26):2515–2524CrossRefPubMed
73.
Zurück zum Zitat Sowers M, Karvonen-Gutierrez CA, Jacobson JA, Jiang Y, Yosef M (2011) Associations of anatomical measures from MRI with radiographically defined knee osteoarthritis score, pain, and physical functioning. J Bone Joint Surg Am 93(3):241–251CrossRefPubMedPubMedCentral Sowers M, Karvonen-Gutierrez CA, Jacobson JA, Jiang Y, Yosef M (2011) Associations of anatomical measures from MRI with radiographically defined knee osteoarthritis score, pain, and physical functioning. J Bone Joint Surg Am 93(3):241–251CrossRefPubMedPubMedCentral
74.
Zurück zum Zitat Spencer SJ, Saithna A, Carmont MR, Dhillon MS, Thompson P, Spalding T (2012) Meniscal scaffolds: early experience and review of the literature. Knee 19(6):760–765CrossRefPubMed Spencer SJ, Saithna A, Carmont MR, Dhillon MS, Thompson P, Spalding T (2012) Meniscal scaffolds: early experience and review of the literature. Knee 19(6):760–765CrossRefPubMed
75.
Zurück zum Zitat Steadman JR, Rodkey WG (2005) Tissue-engineered collagen meniscus implants: 5- to 6-year feasibility study results. Arthroscopy 21(5):515–525CrossRefPubMed Steadman JR, Rodkey WG (2005) Tissue-engineered collagen meniscus implants: 5- to 6-year feasibility study results. Arthroscopy 21(5):515–525CrossRefPubMed
76.
Zurück zum Zitat Stein T, Mehling AP, Welsch F, von Eisenhart-Rothe R, Jager A (2010) Long-term outcome after arthroscopic meniscal repair versus arthroscopic partial meniscectomy for traumatic meniscal tears. Am J Sports Med 38(8):1542–1548CrossRefPubMed Stein T, Mehling AP, Welsch F, von Eisenhart-Rothe R, Jager A (2010) Long-term outcome after arthroscopic meniscal repair versus arthroscopic partial meniscectomy for traumatic meniscal tears. Am J Sports Med 38(8):1542–1548CrossRefPubMed
77.
Zurück zum Zitat Stone KR, Walgenbach AW, Turek TJ, Freyer A, Hill MD (2006) Meniscus allograft survival in patients with moderate to severe unicompartmental arthritis: a 2- to 7-year follow-up. Arthroscopy 22(5):469–478CrossRefPubMed Stone KR, Walgenbach AW, Turek TJ, Freyer A, Hill MD (2006) Meniscus allograft survival in patients with moderate to severe unicompartmental arthritis: a 2- to 7-year follow-up. Arthroscopy 22(5):469–478CrossRefPubMed
78.
Zurück zum Zitat Takeda Y, Ikata T, Yoshida S, Takai H, Kashiwaguchi S (1998) MRI high-signal intensity in the menisci of asymptomatic children. J Bone Joint Surg Br 80(3):463–467CrossRefPubMed Takeda Y, Ikata T, Yoshida S, Takai H, Kashiwaguchi S (1998) MRI high-signal intensity in the menisci of asymptomatic children. J Bone Joint Surg Br 80(3):463–467CrossRefPubMed
79.
Zurück zum Zitat Van Dyck P, Vanhoenacker FM, Gielen JL, Dossche L, Weyler J, Parizel PM (2010) Three-Tesla magnetic resonance imaging of the meniscus of the knee: what about equivocal errors? Acta Radiol 51(3):296–301CrossRefPubMed Van Dyck P, Vanhoenacker FM, Gielen JL, Dossche L, Weyler J, Parizel PM (2010) Three-Tesla magnetic resonance imaging of the meniscus of the knee: what about equivocal errors? Acta Radiol 51(3):296–301CrossRefPubMed
80.
Zurück zum Zitat Vanderhave KL, Moravek JE, Sekiya JK, Wojtys EM (2011) Meniscus tears in the young athlete: results of arthroscopic repair. J Pediatr Orthop 31(5):496–500CrossRefPubMed Vanderhave KL, Moravek JE, Sekiya JK, Wojtys EM (2011) Meniscus tears in the young athlete: results of arthroscopic repair. J Pediatr Orthop 31(5):496–500CrossRefPubMed
81.
Zurück zum Zitat Vangsness CT Jr, Farr J 2nd, Boyd J, Dellaero DT, Mills CR, LeRoux-Williams M (2014) Adult human mesenchymal stem cells delivered via intra-articular injection to the knee following partial medial meniscectomy: a randomized, double-blind, controlled study. J Bone Joint Surg Am 96(2):90–98CrossRefPubMed Vangsness CT Jr, Farr J 2nd, Boyd J, Dellaero DT, Mills CR, LeRoux-Williams M (2014) Adult human mesenchymal stem cells delivered via intra-articular injection to the knee following partial medial meniscectomy: a randomized, double-blind, controlled study. J Bone Joint Surg Am 96(2):90–98CrossRefPubMed
82.
Zurück zum Zitat Verbruggen D, Verschueren T, Tampere T, Almqvist K, Victor J, Verdonk R, Verdonk P (2014) Revision of meniscal transplants: long-term clinical follow-up. Knee Surg Sports Traumatol Arthrosc 22(2):351–356CrossRefPubMed Verbruggen D, Verschueren T, Tampere T, Almqvist K, Victor J, Verdonk R, Verdonk P (2014) Revision of meniscal transplants: long-term clinical follow-up. Knee Surg Sports Traumatol Arthrosc 22(2):351–356CrossRefPubMed
83.
Zurück zum Zitat Verdonk P, Beaufils P, Bellemans J, Djian P, Heinrichs EL, Huysse W, Laprell H, Siebold R, Verdonk R, Actifit Study G (2012) Successful treatment of painful irreparable partial meniscal defects with a polyurethane scaffold: two-year safety and clinical outcomes. Am J Sports Med 40(4):844–853CrossRefPubMed Verdonk P, Beaufils P, Bellemans J, Djian P, Heinrichs EL, Huysse W, Laprell H, Siebold R, Verdonk R, Actifit Study G (2012) Successful treatment of painful irreparable partial meniscal defects with a polyurethane scaffold: two-year safety and clinical outcomes. Am J Sports Med 40(4):844–853CrossRefPubMed
84.
Zurück zum Zitat Verdonk PC, Demurie A, Almqvist KF, Veys EM, Verbruggen G, Verdonk R (2005) Transplantation of viable meniscal allograft. Survivorship analysis and clinical outcome of one hundred cases. J Bone Joint Surg Am 87(4):715–724CrossRefPubMed Verdonk PC, Demurie A, Almqvist KF, Veys EM, Verbruggen G, Verdonk R (2005) Transplantation of viable meniscal allograft. Survivorship analysis and clinical outcome of one hundred cases. J Bone Joint Surg Am 87(4):715–724CrossRefPubMed
85.
Zurück zum Zitat Verdonk R, Verdonk P, Huysse W, Forsyth R, Heinrichs EL (2011) Tissue ingrowth after implantation of a novel, biodegradable polyurethane scaffold for treatment of partial meniscal lesions. Am J Sports Med 39(4):774–782CrossRefPubMed Verdonk R, Verdonk P, Huysse W, Forsyth R, Heinrichs EL (2011) Tissue ingrowth after implantation of a novel, biodegradable polyurethane scaffold for treatment of partial meniscal lesions. Am J Sports Med 39(4):774–782CrossRefPubMed
86.
Zurück zum Zitat Welsch GH, Juras V, Szomolanyi P, Mamisch TC, Baer P, Kronnerwetter C, Blanke M, Fujita H, Trattnig S (2012) Magnetic resonance imaging of the knee at 3 and 7 tesla: a comparison using dedicated multi-channel coils and optimised 2D and 3D protocols. Eur Radiol 22(9):1852–1859CrossRefPubMed Welsch GH, Juras V, Szomolanyi P, Mamisch TC, Baer P, Kronnerwetter C, Blanke M, Fujita H, Trattnig S (2012) Magnetic resonance imaging of the knee at 3 and 7 tesla: a comparison using dedicated multi-channel coils and optimised 2D and 3D protocols. Eur Radiol 22(9):1852–1859CrossRefPubMed
87.
Zurück zum Zitat Wroble RR, Henderson RC, Campion ER, El-Khoury GY, Albright JP (1992) Meniscectomy in children and adolescents. A long-term follow-up study. Clin Orthop Relat Res 279:180–189PubMed Wroble RR, Henderson RC, Campion ER, El-Khoury GY, Albright JP (1992) Meniscectomy in children and adolescents. A long-term follow-up study. Clin Orthop Relat Res 279:180–189PubMed
88.
Zurück zum Zitat Yoon YC, Kim SS, Chung HW, Choe BK, Ahn JH (2007) Diagnostic efficacy in knee MRI comparing conventional technique and multiplanar reconstruction with one-millimeter FSE PDW images. Acta Radiol 48(8):869–874CrossRefPubMed Yoon YC, Kim SS, Chung HW, Choe BK, Ahn JH (2007) Diagnostic efficacy in knee MRI comparing conventional technique and multiplanar reconstruction with one-millimeter FSE PDW images. Acta Radiol 48(8):869–874CrossRefPubMed
89.
Zurück zum Zitat Zaffagnini S, Giordano G, Vascellari A, Bruni D, Neri MP, Iacono F, Kon E, Presti ML, Marcacci M (2007) Arthroscopic collagen meniscus implant results at 6 to 8 years follow up. Knee Surg Sports Traumatol Arthrosc 15(2):175–183CrossRefPubMed Zaffagnini S, Giordano G, Vascellari A, Bruni D, Neri MP, Iacono F, Kon E, Presti ML, Marcacci M (2007) Arthroscopic collagen meniscus implant results at 6 to 8 years follow up. Knee Surg Sports Traumatol Arthrosc 15(2):175–183CrossRefPubMed
90.
Zurück zum Zitat Zaffagnini S, Marcheggiani Muccioli GM, Lopomo N, Bruni D, Giordano G, Ravazzolo G, Molinari M, Marcacci M (2011) Prospective long-term outcomes of the medial collagen meniscus implant versus partial medial meniscectomy: a minimum 10-year follow-up study. Am J Sports Med 39(5):977–985CrossRefPubMed Zaffagnini S, Marcheggiani Muccioli GM, Lopomo N, Bruni D, Giordano G, Ravazzolo G, Molinari M, Marcacci M (2011) Prospective long-term outcomes of the medial collagen meniscus implant versus partial medial meniscectomy: a minimum 10-year follow-up study. Am J Sports Med 39(5):977–985CrossRefPubMed
91.
Zurück zum Zitat Zellner J, Hierl K, Mueller M, Pfeifer C, Berner A, Dienstknecht T, Krutsch W, Geis S, Gehmert S, Kujat R, Dendorfer S, Prantl L, Nerlich M, Angele P (2013) Stem cell-based tissue-engineering for treatment of meniscal tears in the avascular zone. J Biomed Mater Res B 101(7):1133–1142CrossRef Zellner J, Hierl K, Mueller M, Pfeifer C, Berner A, Dienstknecht T, Krutsch W, Geis S, Gehmert S, Kujat R, Dendorfer S, Prantl L, Nerlich M, Angele P (2013) Stem cell-based tissue-engineering for treatment of meniscal tears in the avascular zone. J Biomed Mater Res B 101(7):1133–1142CrossRef
92.
Zurück zum Zitat Zellner J, Mueller M, Berner A, Dienstknecht T, Kujat R, Nerlich M, Hennemann B, Koller M, Prantl L, Angele M, Angele P (2010) Role of mesenchymal stem cells in tissue engineering of meniscus. J Biomed Mater Res A 94(4):1150–1161PubMed Zellner J, Mueller M, Berner A, Dienstknecht T, Kujat R, Nerlich M, Hennemann B, Koller M, Prantl L, Angele M, Angele P (2010) Role of mesenchymal stem cells in tissue engineering of meniscus. J Biomed Mater Res A 94(4):1150–1161PubMed
93.
Zurück zum Zitat Ziegler R, Goebel L, Seidel R, Cucchiarini M, Pape D, Madry H (2015) Effect of open wedge high tibial osteotomy on the lateral tibiofemoral compartment in sheep. Part III: analysis of the microstructure of the subchondral bone and correlations with the articular cartilage and meniscus. Knee Surg Sports Traumatol Arthrosc 23(9):2704–2714CrossRefPubMed Ziegler R, Goebel L, Seidel R, Cucchiarini M, Pape D, Madry H (2015) Effect of open wedge high tibial osteotomy on the lateral tibiofemoral compartment in sheep. Part III: analysis of the microstructure of the subchondral bone and correlations with the articular cartilage and meniscus. Knee Surg Sports Traumatol Arthrosc 23(9):2704–2714CrossRefPubMed
94.
Zurück zum Zitat Zur G, Linder-Ganz E, Elsner JJ, Shani J, Brenner O, Agar G, Hershman EB, Arnoczky SP, Guilak F, Shterling A (2011) Chondroprotective effects of a polycarbonate-urethane meniscal implant: histopathological results in a sheep model. Knee Surg Sports Traumatol Arthrosc 19(2):255–263CrossRefPubMed Zur G, Linder-Ganz E, Elsner JJ, Shani J, Brenner O, Agar G, Hershman EB, Arnoczky SP, Guilak F, Shterling A (2011) Chondroprotective effects of a polycarbonate-urethane meniscal implant: histopathological results in a sheep model. Knee Surg Sports Traumatol Arthrosc 19(2):255–263CrossRefPubMed
Metadaten
Titel
The role of meniscal tissue in joint protection in early osteoarthritis
verfasst von
Rene Verdonk
Henning Madry
Nogah Shabshin
Florian Dirisamer
Giuseppe M. Peretti
Nicolas Pujol
Tim Spalding
Peter Verdonk
Romain Seil
Vincenzo Condello
Berardo Di Matteo
Johannes Zellner
Peter Angele
Publikationsdatum
16.04.2016
Verlag
Springer Berlin Heidelberg
Erschienen in
Knee Surgery, Sports Traumatology, Arthroscopy / Ausgabe 6/2016
Print ISSN: 0942-2056
Elektronische ISSN: 1433-7347
DOI
https://doi.org/10.1007/s00167-016-4069-2

Weitere Artikel der Ausgabe 6/2016

Knee Surgery, Sports Traumatology, Arthroscopy 6/2016 Zur Ausgabe

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.