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Experimental Brain Research

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01.01.2010 | Review

The blindsight saga

verfasst von: Alan Cowey

Erschienen in: Experimental Brain Research | Ausgabe 1/2010

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Abstract

Blindsight is the ability of patients with clinically blind field defects, caused by damage to the primary visual cortex V, to detect, localise and even discriminate visual stimuli that they deny seeing. Blindsight tells us much about the nature of visual processing in the absence of the primary visual cortex and is a paradigmatic example of implicit knowledge. It has attracted widespread interest and debate amongst philosophers, cognitive neuropsychologists and visual neuroscientists. Its downside is that possible artefacts abound, much more so than with examples of implicit memory or deaf hearing and numb touch. Unfortunately the artefacts are still frequently ignored, or dismissed as captious, with the result that many of the genuine qualities of blindsight remain uncertain. Now that blindsight in monkeys has been established the substantial literature on the effects of removing parts or all of V1 in monkeys on the residual physiological cerebral responses to visual stimuli in their field defects is at last directly relevant to human blindsight. Whether blindsight is, or could be, useful in everyday life is the next unsolved problem.

Alexander I, Cowey A (2009) The cortical basis of global motion detection in blindsight. Exp Brain Res 192:407–412PubMed

Azzopardi P, Cowey A (1997) Is blindsight like normal, near-threshold vision? Proc Natl Acad Sci USA 94:14190–14194PubMed

Azzopardi P, Cowey A (1998) Blindsight and visual awareness. Conscious Cogn 7:292–311PubMed

Azzopardi P, Cowey A (2002) Cerebral activity related to guessing and attention during a visual detection task. Cortex 38:833–836

Azzopardi P, Fallah M, Gross CG, Rodman HR (2003) Response latencies of neurons in visual areas MT and MST of monkeys with striate cortex lesions. Neuropsychologia 41:1738–1756PubMed

Barbur JL, Watson JD, Frachowiak RSJ, Zeki S (1993) Conscious visual perception without V1. Brain 116:1293–1302PubMed

Bender MB, Krieger HP (1951) Visual function in perimetrically blind fields. Arch Neurol Psychiat 65:72–79

Bennett MR, Hacker PMS (2003) Philosophical foundations of neuroscience. Blackwell, Oxford, p 461

Benson PJ, Guo L, Blakemore C (1998) Direction discrimination of moving gratings and plaids and coherence of dot displays without primary visual cortex (V1). Eur J NeuroSci 10:3767–3772PubMed

Blythe IM, Kennard C, Ruddock KH (1987) Residual vision in patients with retrogeniculate lesions of the visual pathways. Brain 110:887–905PubMed

Braddick OJ, Atkinson J, Hood B, Harkness W, Jackson G, Vargha-Khadem F (1992) Possible blindsight in infants lacking one cerebral hemisphere. Nature 360:461–463PubMed

Bridge H, Thomas O, Jbabdi S, Cowey A (2008) Changes in connectivity after visual cortical brain damage underlie altered visual function. Brain 131:1433–1444PubMed

Brindley GS, Gautier-Smith PC, Lewin W (1969) Cortical blindness and the functions of the non-geniculate fibres of the optic tracts. J Neurol Neurosurg Psychiat 32:259–264PubMed

Brown LE, Kroliczac G, Demonet J-F, Goodale MA (2007) A hand in blindsight: hand placement near target improves size perception in the blind visual field. Neuropsychologia 46:786–802PubMed

Bullier J, Girard P, Salin P-A (1994) The role of area 17 in the transfer of information to extrastriate visual cortex. In: Peters A, Rockland KS (eds) Cer cortex, vol 10. Plenum Press, New York, pp 301–330

Buzsaki G (2006) Rythms of the brain. Oxford University Press, Oxford

Buzsaki G, Draguhn A (2004) Neuronal oscillations in cortical networks. Science 304:1926–1929PubMed

Campion J (2007) Blindsight–Fact or Myth? Psychologist 20:207–208

Campion J, Latto R, Smith YM (1983) Is blindsight an effect of scattered light, spared cortex, and near-threshold vision? Behav Brain Sci 3:423–486

Chalmers D (1996) The conscious mind: in search of a fundamental theory. Oxford University Press, Oxford

Clifford CWG, Arabzadeh E, Harris JA (2008) Getting technical about awareness. Trends Cog Sci 12:54–58

Corbetta M, Marzi CA, Tassinari G, Aglioti S (1990) Effectiveness of different task paradigms in revealing blindsight. Brain 113:603–616PubMed

Cowey A (1967) Perimetric study of visual field defects in monkeys after cortical and retinal ablations. Quart J Exp Psychol 19:232–245

Cowey A (1974) Atrophy of retinal ganglion cells after removal of striate cortex in a rhesus monkey. Perception 3:257–260PubMed

Cowey A (2004) Fact, artefact and myth about blindsight. Quart J Exp Psychol 57A:577–609

Cowey A, Azzopardi P (2001) Is blindsight motion blind? In: de Gelder B, de Haan E, Heywood CA (eds) Out of mind. Oxford University Press, Oxford, pp 87–103

Cowey A, Stoerig P (1989) Projection patterns of surviving neurons in the dorsal lateral genicualte nucleus following discrete lesions of striate cortex: implications for residual vision. Exp Brain Res 75:631–638PubMed

Cowey A, Stoerig P (1995) Blindsight in monkeys. Nature 373:247–249PubMed

Cowey A, Stoerig P (1997) Visual detection in monkeys with blindsight. Neuropsychologia 35:929–939PubMed

Cowey A, Stoerig P (1999) Spectral sensitivity in hemianopic macaque monkeys. Eur J NeuroSci 11:2114–2120PubMed

Cowey A, Stoerig P (2003) Stimulus cueing in blindsight. Prog Brain Res 144:261–277

Cowey A, Walsh V (2000) Magnetically induced phosphenes in sighted, blind and blindsighted observers. NeuroReport 11:3269–3273PubMed

Cowey A, Weiskrantz L (1963) A perimetric study of visual field defects in monkeys. Quart J Exp Psychol 15:91–115

Cowey A, Stoerig P, Perry VH (1989) Transneuronal retrograde degeneration of retinal ganglion cells after damage to striate cortex in macaque monkeys: selective loss of Pß cells. Neuroscience 29:65–80PubMed

Cowey A, Stoerig P, Bannister M (1994) Retinal ganglion cells labelled from the pulvinar nucleus in macaque monkeys. Neuroscience 61:691–705PubMed

Cowey A, Stoerig P, Le Mare C (1998) Effects of unseen stimuli on reaction times to seen stimuli in monkeys with blindsight. Conscious Cogn 7:312–323PubMed

Cowey A, Stoerig P, Williams C (1999) Variance in transneuronal retrograde ganglion cell degeneration in monkeys after removal of striate cortex: effects of size of the cortical lesion. Vision Res 39:3642–3652PubMed

Cowey A, Johnson H, Stoerig P (2001) The retinal projection to the pregeniculate nucleus in normal and destriate monkeys. Eur J NeuroSci 13:279–290PubMed

Dacey DM, Lee BB (1994) The blue-ON opponent pathway in primate retina originates from a distinct bistratified ganglion cell type. Nature 367:731–735PubMed

De Gelder B, Vroomen J, Pourtois G, Weiskrantz L (1999) Non-conscious recognition of affect in the absence of striate cortex. NeuroReport 10:3759–3763PubMed

De Gelder B, Vroomen J, Pourtois G (2001) Covert affective cognition and affective blindsight. In: de Gelder B, de Haan E, Heywood CA (eds) Out of mind. Oxford University Press, Oxford, England, pp 205–221

De Gelder B, Tamietto M, van Boxtel G, Goebel R, Sahraie A, van den Stock J, Steinen BMC, Weiskrantz L, Pegna A (2009) Intact navigation skills after bilateral loss of striate cortex. Curr Biol 18:R1128–R1129

Dienes Z, Scott R (2005) Measuring unconscious knowledge: distinguishing structural knowledge and judgement knowledge. Psychol Res 69:338–351PubMed

Dineen J, Hendrickson A (1981) Age-correlated differences in the amount of retinal degeneration after striate cortex lesions in monkeys. Invest Ophthalmol 21:749–752

Dineen J, Keating EG (1981) The primate visual system after bilateral removal of striate cortex. Survival of complex pattern vision. Exp Brain Res 41:338–345PubMed

Dineen J, Hendrickson A, Keating EG (1982) Alterations of retinal inputs following striate cortex removal in adult monkey. Exp Brain Res 47:446–456PubMed

Dodds WJ (1885) On some central affections of vision. Part I. Brain 8:21–39

Evans S, Azzopardi P (2007) Evaluation of a ‘bias-free’ measure of awareness. Spat Vis 20:61–77PubMed

Farah MJ, Soso MJ, Dashieff RM (1992) Visual angle of the mind’s eye before and after unilateral occipital lobectomy. J Exp Psychol Hum Percep Perform 18:241–246

Faubert J, Diaconu V (2001) From visual consciousness to spectral absorption in the human retina. Prog Brain Res 134:300–409

Faubert J, Diaconu V, Ptito M, Ptito A (1999) Residual vision in the blind field of hemidecorticated humans predicted by a diffusion scatter model and selective spectral absorption of the human eye. Vision Res 39:149–157PubMed

ffytche DH, Guy CN, Zeki S (1995) The parallel visual motion inputs into areas V1 and V5 of human cerebral cortex. Brain 118:1375–1394PubMed

Goebel R, Muckli L, Zanella FE, Singer W, Stoerig P (2001) Sustained extrastriate cortical activation without visual awareness revealed by fMRI studies of hemianopic patients. Vision Res 41:1459–1474PubMed

Gold I (1999) Does the 40-Hz oscillation play a role in visual consciousness? Conscious Cogn 8:186–195PubMed

Gonzalez-Andino SL, Grave de Peralta Menendez R, Khateb A, Landis T, Pegna AJ (2009) Electrophysiologicl correlates of affective blindsight. NeuroImage 44:581–589

Green DM, Swets JA (1966) Signal detection theory and psychophysics. Wiley, New York

Hackley SA, Johnson SL (1996) Distinct early and late components of the photic blink relex: I. Response characteristics in patients with retrogeniculate lesions. Pathophysiol 33:239–251

Heide W, Koenig E, Dichgans J (1990) Optokinetic nystagmus, self motion sensation and their after effects in patients with occipito-parietal lesions. Clin Vis Sci 5:145–156

Hendry SHC, Reid RC (2000) The koniocellular pathway in primate vision. Ann Rev Neurosci 23:127–153PubMed

Henriksson L, Raninen A, Näsänen R, Hyvärinen L, Vanni S (2006) Training induced cortical representation of a hemianopic field. J Neurol Neurosurg Psychiat 78:74–81PubMed

Holliday IE, Anderson SJ, Harding GFA (1997) Magnetoencephalographic evidence for non-geniculostriate visual input to human cortical area V5. Neuropsychologia 35:1139–1146PubMed

Holmes G (1918) Disturbances of vision by cerebral lesions. Brit J Ophthal 2:353–384PubMed

Horton JC (2005) Disappointing results from NovaVision’s visual restoration therapy. Brit J Ophthalmol 89:1–2

Humphrey NK (1974) Vision in a monkey without striate cortex: a case study. Perception 3:241–255PubMed

Huxlin KR (2008) Perceptual plasticity in damaged adult visual systems. Vision Res 48:2154–2166PubMed

Huxlin KR, Pasternak T (2004) Training induced recovery of visual motion perception after extrastriate cortical damage in the adult cat. Cer Cortex 14:81–90

Huxlin KR, Martin T, Kelly K, Riley M, Friedman DI, Burgin WS, Hayhoe M (2009) Perceptual relearning of complex visual motion after V1 damage in humans. J Neurosci 29:3981–3991PubMed

Hyman J (1991) Visual experience and blindsight. In: Hyman J (ed) Investigating psychology: sciences of the mind after Wittgenstein. Routledge, London, pp 166–200

Innocenti GM, Kiper DC, Knyazeva MG, Deonna TW (1999) Nature and limits of cortical developmental plasticity in a child. J Rest Neurol Neurosci 15:219–227

Jindahra P, Petrie A, Plant GT (2009) Retrograde trans-synaptic retinal ganglion cell loss identified by optical coherence tomography. Brain. doi:10.1093/brain/awp001)

Kasten E, Sabel BA (1995) Visual field enlargement after computer-training in brain-damaged patients with homonymous deficits—an open pilot trial. Rest Neurol Neurosci 8:113–127

Kasten E, Wüst S, Behrens-Baumann W, Sabel BA (1998) Computer-based training for the treatment of partial blindness. Nature Med 4:1083–1087PubMed

Keating EG (1975) Effects of striate and prestriate lesions on the monkey’s ability to locate and discriminate visual forms. Exp Neurol 47:16–25PubMed

Keating EG (1979) Rudimentary color vision in the monkey after removal of striate and preoccipital cortex. Brain Res 179:379–384PubMed

Kentridge RW, Heywood CA, Weiskrantz L (1999a) Effects of temporal cueing on residual visual discrimination in blindsight. Neuropsychologia 37:479–483PubMed

Kentridge RW, Heywood CA, Weiskrantz L (1999b) Attention without awareness in blindsight. Proc Roy Soc Lond B 266:1805–1911

Khalsa SS, Rudrauf D, Sandesara C, Olshansky B, Tranel D (2009) Bolus isoproterenol infusions provide a reliable method for assessing interoceptive awareness. Int J Psychophysiol 72:34–45PubMed

King SM, Cowey A (1992) Defensive responses to looming visual stimuli in monkeys with unilateral striate cortex ablation. Neuropsychologia 30:1017–1024PubMed

King SM, Azzopardi P, Cowey A, Oxbury J, Oxbury S (1996) The role of light scatter in the residual visual sensitivity of patients with complete cerebral hemispherectomy. Visual Neurosci 13:1–13

Kiper DC, Zesiger P, Maeder P, Deonna T, Innocenti GM (2002) Vision after early–onset lesions of the occipital cortex: 1. Neuropsychological and psychophysical studies. Neural Plasticity 9:1–25PubMed

Klüver H (1941) Visual functions after removal of the occipital lobes. J Psychol 11:23–45

Kölmel HW (1985) Compex visual hallucinations in the hemianopic field. J Neurol Neurosurg Psychiat 48:293–298

Kunimoto C, Miller J, Pashler H (2001) Confidence and accuracy of near-threshold discrimination responses. Conscious Cogn 10:294–340PubMed

Leporé F, Cardu B, Rasmussen T, Malmo RB (1975) Rod and cone sensitivity in destriate monkeys. Brain Res 93:203–221PubMed

Macmillan NA, Creelman CD (1991) Detection theory: a user’s guide. Cambridge University Press, Cambridge

Macphail EM (1998) The evolution of consciousness. Oxford University Press, Oxford

Magoun HW, Ranson SW (1935) The central path of the light reflex. Arch Ophthalmol 13:791–811

Malmo RB (1966) Effects of striate cortex ablation on intensity discrimination and spectral intensity distribution in the rhesus monkey. Neuropsychologia 4:9–16

Marcel AJ (1983) Conscious and unconscious perception: an approach to the relations between phenomenal experience and perceptual processes. Cog Psychol 15:238–300

Marcel AJ (1998) Blindsight and shape perception: deficit of visual consciousness or of visual function? Brain 121:1565–1588PubMed

Marzi CA, Tassinari G, Aglioti S, Lutzemberger L (1986) Spatial summation across the vertical meridian in hemianopics: a test of blindsight. Neuropsychologia 30:783–795

Mihailovic LT, Cupic D, Dekleva N (1971) Changes in the number of neurons and glial cells in the lateral geniculate nucleus of the monkey during retrograde cell degeneration. J Comp Neurol 142:223–230

Mole C, Kelly S (2006) On the demonstration of blindsight in monkeys. Mind and Language 21:475–483

Moore T, Rodman HR, Repp AB, Gross CG (1995) Localization of visual stimuli after striate cortex damage in monkeys: parallels with human blindsight. Proc Natl Acad Sci USA 92:8215–8218PubMed

Moore T, Rodman HR, Gross CG (1998) Man, monkey and blindsight. Neuroscientist 4:227–230

Morris JS, DeGelder B, Weiskrantz L, Dolan RJ (2001) Differential extrageniculate and amygdala responses to presentation of emotional faces in a cortically blind field. Brain 124:1241–1252PubMed

Murphey DK, Maunsell JHR (2007) Behavioral detection of electrical microstimulation of cortical visual areas. Curr Biol 17:862–867PubMed

Murphey DK, Maunsell JHR, Beauchamp MS, Yoshor D (2009) Perceiving electrical stimulation of identified human visual areas. Proc Natl Acad Sci USA 106:5389–5393PubMed

Pasik P, Pasik T (1964) Oculomotor function in monkeys with lesions of the cerebrum and the superior colliculi. In: Bender MB (ed) The oculomotor system. Hoeber, New York, pp 40–80

Pasik P, Pasik T (1982) Visual functions in monkeys after total removal of visual cerebral cortex. Contrib Sensory Physiol 7:147–200

Pasik P, Pasik T, Schilder P (1969) Extrageniculostriate vision in the monkey: discrimination of luminous flux-equated figures. Exp Neurol 24:421–437PubMed

Pasik P, Pasik T, Valciukas JA (1970) Nystagmus induced by stationary repetitive light flashes in monkeys. Brain Res 19:313–317PubMed

Pegna AJ, Khateb A, Lazeyras F, Seghier ML (2005) Discriminating emotional faces without primary visual cortices involves the right amygdala. Nat Neurosci 8:24–25PubMed

Perenin MT (1991) Discrimination of motion direction in perimetrically blind fields. NeuroReport 2:397–400PubMed

Perenin MT, Jeannerod M (1975) Residual visual functions in cortically blind hemifields. Neuropsychologia 13:1–7PubMed

Perenin MT, Rossetti Y (1996) Grasping without form discrimination in a hemianopic field. NeuroReport 7:793–797PubMed

Perenin MT, Ruel J, Hecaen H (1980) Residual visual capacities in a case of cortical blindness. Cortex 16:605–612PubMed

Persaud N, Cowey A (2008) Blindsight is unlike normal conscious vision: evidence from an exclusion task. Conscious Cogn 17:1050–1055PubMed

Persaud N, McLeod P, Cowey A (2007) Post-decision wagering objectively measures awareness. Nature Neurosci 10:257–261PubMed

Pizzamiglio L, Antonucci G, Francia A (1984) Response of the cortically blind hemifields to a moving visual scene. Cortex 20:89–99PubMed

Pöppel E (1986) Long-range colour-generating interactions across the retina. Nature 320:523–525PubMed

Pöppel E, Frost D, Held R (1973) Residual visual function after brain wounds involving the central visual pathways in man. Nature, London 243:295–296

Rafal R, Smith W, Krantz J, Cohen A, Brennan C (1990) Extrageniculate vision in hemianopic humans: saccade inhibition by signals in the blind field. Science 250:118–121PubMed

Rao A, Nobre AC, Cowey A (2001) Disruption of evoked potentials following a V1 lesion: implications for blindsight. In: De Gelder B, de Haan E, Heywood CA (eds) Out of mind. Oxford University Press, Oxford, pp 69–86

Reinhard J, Schreiber A, Schiefer U, Kasten E, Sabel BA, Kenkel S, Vonthein R, Trauzettel-Klosinski S (2005) Does visual restitution training change absolute homonomous visual field defects? A fundus controlled study. Br J Ophthalmol 89:30–35PubMed

Richards W (1973) Visual processing in scotomata. Exp Brain Res 17:333–347PubMed

Riddoch G (1917) Dissociation of visual perceptions due to occipital injuries, with especial reference to appreciation of movement. Brain 40:15–57

Rodman HR, Gross CG, Albright TD (1989) Afferent basis of visual response properties in area MT of the macaque: I. effects of striate cortex removal. J Neurosci 9:2033–2050PubMed

Rodman HR, Gross CG, Albright TD (1990) Afferent basis of visual response properties in area MT of the macaque. II. Effects of superior colliculus removal. J Neurosci 10:1154–1164PubMed

Rosenblum LD, Gordon M, Jarquin L (2000) Echolocating distance by moving and stationary listeners. Ecol Psychol 12:181–186

Sahraie A, Weiskrantz L, Barbur JL, Simmons A, Williams SCR, Brammer MJ (1997) Pattern of neuronal activity associated with conscious and unconscious processing of visual signals. Proc Natl Acad Sci USA 94:9406–9411PubMed

Sanders MD, Warrington EK, Marshall J, Weiskrantz L (1974) ‘Blindsight’: vision in a field defect. Lancet 1:707–708PubMed

Schilder P, Pasik P, Pasik T (1971) Extrageniculostriate vision in the monkey. II. Demonstration of brightness discrimination. Brain Res 32:383–389PubMed

Schilder P, Pasik P, Pasik T (1972) Extrageniculostriate vision in the monkey. III. Circle vs triangle and ‘red vs green’ discrimination. Exp Brain Res 14:436–448PubMed

Schmid MC, Panagiotaropoulos T, Augath MA, Logothetis NK, Smirnakis SM (2009) Visually driven activation in macaque areas V2 and V3 without input from the primary visual cortex. PLoS ONE 4(e5527):1–14CrossRef

Schuett S, Heywood CA, Kentridge RW, Zihl J (2008) Rehabilitation of hemianopic dyslexia: are words necessary for re-learning oculomotor control? Brain 131:3156–3168PubMed

Schurger A, Cowey A, Tallon-Baudry C (2006) Induced gamma-band oscillations correlate with awareness in hemianopic patient GY. Neuropsychologia 44:1796–1803PubMed

Schurger A, Cowey A, Cohen J, Treisman A, Tallon-Baudry C (2008) Distinct and independent correlates of attention and awareness in a hemianopic patient. Neuropsychologia 46:2189–2197PubMed

Schwitzgebel E, Gordon MS (2000) How well do we know our own conscious experience? The case of human echolocation. Philos Topics 28:235–246

Silvanto J, Cowey A, Lavie N, Walsh V (2007) Making the blindsighted see. Neuropsychologia 45:3346–3350PubMed

Silvanto J, Cowey A, Walsh V (2008) Inducing conscious perception of colour in blindsight. Curr Biol 18:950–951

Silvanto J, Walsh V, Cowey A (2009) Abnormal functional connectivity between ipsilesional V5/MT + and contralesional striate cortex (V1) in blindsight. Exp Brain Res 193:645–650PubMed

Singer W (1993) Synchronisation of cortical activity and its putative role in information processing and learning. Ann Rev Physiol 55:349–374

Stoerig P (2006) Blindsight, conscious vision, and the role of the primary visual cortex. Prog Brain Res 155:217–234PubMed

Stoerig P (2007) Functional rehabilitation of partial cortical blindness. Restorative Neurol Neurosci 25:1–14

Stoerig P, Cowey A (1989) Residual target detection as a function of stimulus size. Brain 112:1123–1139PubMed

Stoerig P, Cowey A (1991) Increment-threshold spectral sensitivity in blindsight. Brain 114:1487–1512PubMed

Stoerig P, Cowey A (1992) Wavelength discrimination in blindsight. Brain 115:425–444PubMed

Stoerig P, Cowey A (1997) Blindsight in man and monkey. Brain 120:535–559PubMed

Stoerig P, Cowey A (2009) Blindsight. In: Baynes T, Cleermans A, Wilken P (eds) Oxford companion to consciousness. Oxford University Press, Oxford, pp 112–116

Stoerig P, Fahle M (1995) Apparent motion across a scotoma: an implicit test of blindsight. Eur J Neurosci Suppl 8:76

Stoerig P, Pöppel E (1986) Eccentricity-dependent residual target detection in visual field defects. Exp Brain Res 64:469–475PubMed

Stoerig P, Hubner M, Pöppel E (1985) Signal detection analysis of residual vision in a field defect due to a post-geniculate lesion. Neuropsychologia 23:589–599PubMed

Stoerig P, Zontanou A, Cowey A (2002) Aware or unaware: assessment of cortical blindness in four men and a monkey. Cer Cortex 12:565–574

Supa M, Cotzin M, Dallenbach KM (1944) Facial vision: the perception of obstacles by the blind. Am J Psychol 57:133–183

ter Braak JG, van Vliet AGM (1963) Sub-cortical optokinetic nystagmus in the monkey. Psychiat Neurol Neurochirurg 66:277–283

ter Braak JWG, Schenk VWD, van Vliet AGM (1971) Visual reactions in a case of long-standing cortical blindness. J Neurol Neurosurg Psychiat 34:140–147

Theoret H, Boire D, Herbin M, Ptito M (2001) Anatomical sparing in the superior colliculus of hemispherectomized monkeys. Brain Res 16:274–280

Tomaiuolo F, Ptito M, Marzi CA, Paus T, Ptito A (1997) Blindsight in hemsipherectomized patients as revealed by spatial summation across the vertical meridian. Brain 120:795–803PubMed

Treisman M (1964) The effect of one stimulus on the threshold of another: an application of signal detectability theory. Brit J Statistical Psychol 17:15–35

Trevethan CT, Sahraie A, Weiskrantz L (2007) Can blindsight be superior to ‘sighted sight’? Cognition 103:491–501PubMed

Van Buren JM (1963) Trans-synaptic retrograde degeneration in the visual system of primates. J Neurol Neurosurg Psychiat 34:140–147

Van Hof-van Duin J, Mohn G (1983) Optokinetic and spontaneous nystagmus in children with neurological disorders. Behav Brain Res 10:163–175PubMed

Weiskrantz L (1963) Contour discrimination in a young monkey with striate cortex ablation. Neuropsychologia 1:145–164

Weiskrantz L (1987) Residual vision in a scotoma: follow-up study of form discrimination. Brain 110:77–92PubMed

Weiskrantz L (1998) Consciousness and commentaries. In: Towards a science of consciousness II—the second Tucson discussions and debates, M.I.T. Press, Cambridge, pp 371–377

Weiskrantz L (2009) Blindsight: a case study spanning 35 years and new developments, 3rd edn. Oxford University Press, Oxford, p 255

Weiskrantz L, Warrington EK, Sanders MD, Marshall J (1974) Visual capacity in the hemianopic field following a restricted cortical ablation. Brain 97:709–728PubMed

Weiskrantz L, Cowey A, Passingham C (1977) Spatial responses to brief stimuli by monkeys with striate cortex ablations. Brain 100:655–670PubMed

Weiskrantz L, Barbur JL, Sahraie A (1995) Parameters affecting conscious versus unconscious visual discrimination in a patient with damage to the visual cortex (V1). Proc Natl Acad Sci USA 92:6122–6126PubMed

Weiskrantz L, Cowey A, Barbur JL (1999) Differential pupillary constriction and awareness in the absence of striate cortex. Brain 122:1533–1538PubMed

Weiskrantz L, Rao A, Hodinott-Hill I, Nobre AC, Cowey A (2003) Brain potentials associated with conscious after effects induced by unseen stimuli in a blindsight subject. Proc Nat Acad Sci USA 100:10500–10505PubMed

Weller RE, Kaas JH (1989) Parameters affecting the loss of ganglion cells of the retina following ablations of striate cortex in primates. Vis Neurosci 3:327–342PubMed

Wilbrand H, Sänger A (1900) Die Neurologie des Auges, vol III. JF Bergmann, Wiesbaden

Wilson ME (1967) Spatial and temporal summation in impaired regions of the visual field. J Physiol 189:189–208PubMed

Zeki S, ffytche DH (1998) The Riddoch syndrome: insights into the neurobiology of conscious vision. Brain 121:25–45PubMed

Zihl J, von Cramon D (1985) Visual field recovery from scotomota in patients with postgeniculate damage. Brain 108:335–365PubMed

Titel: The blindsight saga
verfasst von: Alan Cowey
Publikationsdatum: 01.01.2010
Verlag: Springer-Verlag
Erschienen in: Experimental Brain Research / Ausgabe 1/2010
Print ISSN: 0014-4819
Elektronische ISSN: 1432-1106
DOI: https://doi.org/10.1007/s00221-009-1914-2

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